التداخل بين أمبيسيلين وسولباكتام وبروبينيسيد

Drug Interactions Probenecid decreases the renal tubular secretion of ampicillin and sulbactam.

Concurrent use of probenecid with UNASYN may result in increased and prolonged blood levels of ampicillin and sulbactam.

Drug Interactions When probenecid is used to elevate plasma concentrations of penicillin or other beta-lactams, or when such drugs are given to patients taking probenecid therapeutically, high plasma concentrations of the other drug may increase the incidence of adverse reactions associated with that drug.

In the case of penicillin or other beta-lactams, psychic disturbances have been reported.