التداخل بين أتينولول وكلورثاليدون وميتولازون

Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy.

Dosage adjustments of other antihypertensives may be necessary.

Anticoagulants Metolazone, as well as other thiazide-like diuretics, may affect the hypoprothrombinemic response to anticoagulants; dosage adjustments may be necessary.

Other Antihypertensives When metolazone tablets, USP, are used with other antihypertensive drugs, care must be taken, especially during initial therapy.

Because of its relative beta 1 -selectivity, however, atenolol and chlorthalidone may be used with caution in patients with bronchospastic disease who do not respond to or cannot tolerate, other antihypertensive treatment.

Drug Interactions Atenolol and chlorthalidone may potentiate the action of other antihypertensive agents used concomitantly.

Other Precautions In patients receiving thiazides, sensitivity reactions may occur with or without a history of allergy or bronchial asthma.