التداخل بين بوسبيرون وفوسابريبيتانت

Other inhibitors and inducers of CYP3A4: Substances that inhibit CYP3A4, such as ketoconazole or ritonavir, may inhibit buspirone metabolism and increase plasma concentrations of buspirone while substances that induce CYP3A4, such as dexamethasone or certain anticonvulsants (phenytoin, phenobarbital, carbamazepine), may increase the rate of buspirone metabolism.

Consequently, when administered with a potent inhibitor of CYP3A4, a low dose of buspirone used cautiously is recommended.