التداخل بين بوتالبيتال وأسبرين وكافيين وكودايين ونابروكسين وإيزوميبرازول

• History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.

History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs.

Exacerbation of Asthma Related to Aspirin Sensitivity : Naproxen and esomeprazole magnesium delayed-release tablets are contraindicated in patients with aspirin-sensitive asthma.

Concomitant NSAID Use : Do not use naproxen and esomeprazole magnesium delayed-release tablets with other naproxen-containing products or other non-aspirin NSAIDs.

Exacerbation of Asthma Related to Aspirin Sensitivity A subpopulation of patients with asthma may have aspirin-sensitive asthma which may include chronic rhinosinusitis complicated by nasal polyps; severe, potentially fatal bronchospasm; and/or intolerance to aspirin and other NSAIDs.

Examples: Ketorolac, ibuprofen, naproxen, diclofenac Corticosteroids Clinical Impact: In patients receiving concomitant corticosteroids and chronic use of aspirin, withdrawal of corticosteroids may result in salicylism because corticosteroids enhance renal clearance of salicylates and their withdrawal is followed by return to normal rates of renal clearance.