التداخل بين الكالسيوم وريزيدرونات

Calcium supplements, antacids, magnesium-based supplements or laxatives, and iron preparations interfere with the absorption of Risedronate sodium delayed-release and should not be taken together.

Calcium Supplements/Antacids When Risedronate sodium delayed-release was administered following breakfast, the co-administration of a tablet containing 600 mg of elemental calcium and 400 international units vitamin D reduced risedronate bioavailability by approximately 38% [ see Clinical Pharmacology (12.3) ] .

Instruct patients to take supplemental calcium and vitamin D if their dietary intake is inadequate.

Calcium supplements, antacids, proton pump inhibitors (PPIs), H 2 blockers, magnesium-based supplements or laxatives, and iron preparations interfere with the absorption of Risedronate sodium delayed-release ( 7.1 , 7.2 )

الكالسيوم يرتبط بهذه الأدوية في الأمعاء وقد يقلّص بشدة الكمية الممتصة منها؛ افصل بين الجرعات.

النص الأصلي للنشرة (بالإنجليزية) Calcium binds these drugs in the gut and can sharply cut how much is absorbed; separate the doses.