التداخل بين كاربامازيبين وليثيوم

Lithium Concomitant administration of EQUETRO and lithium can increase the risk of neurotoxic adverse reactions.

Consider reducing the dose of lithium or EQUETRO when using these drugs concomitantly.

Cytochrome (CYP) 3A4 inhibitors, epoxide hydrolase inhibitors, CYP3A4 inducers, drugs metabolized by CYP1A2 or CYP3A4 (oral contraceptives, delavirdine, nefazodone), phenytoin, CNS depressants, lithium, chloroquine, mefloquine ( 7.1 , 7.2 , 7.3 )

Methyldopa, Phenytoin and Carbamazepine Clinical Impact: Concomitant use may increase risk of adverse reactions of these drugs.

Intervention: Monitor patients closely for adverse reactions of methyldopa, phenytoin, and carbamazepine.