التداخل بين كلوروثيازيد وفينترمين وتوبيرامات

In addition, when phentermine and topiramate extended-release capsules are used in conjunction with nonpotassium sparing diuretics this may further potentiate potassium-wasting.

…phentermine and topiramate extended-release capsules dosage reduction or discontinuation if cognitive dysfunction persists [see Warnings and Precautions (5.5) ] Non-Potassium Sparing Diuretics Clinical Impact Concurrent use of phentermine and topiramate extended-release capsules with non-potassium sparing diuretics may potentiate the potassium-wasting action of…

Intervention When phentermine and topiramate extended-release capsules are used concomitantly with non-potassium-sparing diuretics, measure potassium before and during phentermine and topiramate extended-release capsules treatment [see Warnings and Precautions (5.12) and Clinical Pharmacology (12.3) ] .

Non-potassium Sparing Diuretics : May potentiate hypokalemia.