التداخل بين سيناكالسيت وفوسامبرينافير

Co-administration with a strong CYP3A4 inhibitor may increase serum levels of cinacalcet.

Dose adjustment of Sensipar may be required if a patient initiates or discontinues therapy with a strong CYP3A4 inhibitor (e.g., ketoconazole, itraconazole).

Strong CYP3A4 Inhibitors Cinacalcet is partially metabolized by CYP3A4.

Because ritonavir is a CYP2D6 inhibitor, clinically significant interactions with drugs metabolized by CYP2D6 are possible when coadministered with fosamprenavir calcium plus ritonavir.