التداخل بين كلونازيبام وتريهكسيفينيديل

Concurrent use of alcohol or other CNS depressants with trihexyphenidyl may cause increased sedative effects.

In a study in which the 2 mg clonazepam orally disintegrating tablet was administered with and without propantheline (an anticholinergic agent with multiple effects on the GI tract) to healthy volunteers, the AUC of clonazepam was 10% lower and the C max of clonazepam was 20% lower when the orally disintegrating tablet was given with propantheline compared to…