التداخل بين كلوبيدوغريل وإيترافيرين

CYP2C19 inhibitors: Avoid concomitant use of omeprazole or esomeprazole.

The metabolism of clopidogrel can also be impaired by drugs that inhibit CYP2C19, such as omeprazole or esomeprazole.

CYP2C19 Inhibitors Clopidogrel is metabolized to its active metabolite in part by CYP2C19.

However, at high concentrations in vitro , clopidogrel inhibits CYP2C9.

Alternatives to clopidogrel should be considered.

Platelet aggregation inhibitors: clopidogrel ↓ clopidogrel (active) metabolite Activation of clopidogrel to its active metabolite may be decreased when clopidogrel is co-administered with Etravirine.