التداخل بين دانازول وتريبتوريلين

Tumor Flare: Transient increase in serum testosterone levels can occur within the first few weeks of treatment.

Effect on QT/QTc Interval: Androgen deprivation therapy may prolong the QT interval.

Tumor Flare Initially, triptorelin (TRELSTAR), like other GnRH agonists, causes a transient increase in serum testosterone levels [ see Clinical Pharmacology (12.2) ].

Effect on QT/QTc Interval Androgen deprivation therapy with TRELSTAR may prolong the QT/QTc interval.

Providers should consider whether the benefits of androgen deprivation therapy outweigh the potential risks in patients with congenital long QT syndrome, congestive heart failure, frequent electrolyte abnormalities, and in patients taking drugs known to prolong the QT interval.