التداخل بين ديكسميثيل فينيدات وغوانفاسين

• Antihypertensive Drugs: Monitor blood pressure.

Adjust dosage of antihypertensive drug as needed ( 7.1 ).

Antihypertensive Drugs Clinical impact Focalin XR may decrease the effectiveness of drugs used to treat hypertension [see Warnings and Precautions ( 5.3 )].

Intervention Monitor blood pressure and adjust the dosage of the antihypertensive drug as needed.

In these cases, high-dosage guanfacine was discontinued; concomitant stimulant use was also reported, which may potentially increase hypertensive response upon abrupt discontinuation of guanfacine.

If abrupt discontinuation occurs (especially with concomitant stimulant use), patients should be closely followed for rebound hypertension.