التداخل بين ديفلونيزال وليوثيرونين

An initial increase in serum FT4 is followed by return of FT4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T4 levels may decrease by as much as 30%.

Salicylates (>2 g/day) Salicylates inhibit binding of T4 and T3 to TBG and transthyretin.

Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs Fenamates These drugs may cause protein binding site displacement.