التداخل بين ديلتيازيم وميتوبرولول

Concomitant use of diltiazem with beta-blockers or digitalis may result in additive effects on cardiac conduction.

• Beta-blockers, digitalis, and other agents known to impair cardiac contractility and conduction may increase risk for hypotension, bradycardia, and heart failure.

Experience with the use of diltiazem in combination with beta-blockers in patients with impaired ventricular function is limited.

Concomitant use of glycosides, clonidine, and diltiazem and verapamil with beta-blockers can increase the risk of bradycardia.

Digitalis glycosides, clonidine, diltiazem, and verapamil slow atrioventricular conduction and decrease heart rate.

Because of its relative beta 1 cardio-selectivity, however, Metoprolol Tartrate Tablets may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment.