التداخل بين ديفينهيدرامين وتيمسيروليموس

At the discretion of the physician, treatment may be resumed with the administration of an H 1 -receptor antagonist (such as diphenhydramine), if not previously administered [see Dosage and Administration (2.2) ] , and/or an H 2 -receptor antagonist (such as intravenous famotidine 20 mg or intravenous ranitidine 50 mg) approximately 30 minutes before restarting…

TORISEL should be used with caution in patients with known hypersensitivity to an antihistamine, or patients who cannot receive an antihistamine for other medical reasons.

• To treat hypersensitivity reactions, stop TORISEL and treat with an antihistamine.

An H 1 antihistamine should be administered to patients before the start of the intravenous temsirolimus infusion.