التداخل بين ديفالبروكس (فالبروات) ووارفارين

Dosage adjustment of amitriptyline/nortriptyline, propofol, warfarin, and zidovudine may be necessary if used concomitantly with Depakote ER ( 7.2 )

Warfarin In an in vitro study, valproate increased the unbound fraction of warfarin by up to 32.6%.

The therapeutic relevance of this is unknown; however, coagulation tests should be monitored if valproate therapy is instituted in patients taking anticoagulants.