التداخل بين دوكسيركالسيفيرول وإبليرينون

Risk may be increased when used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds.

Hypercalcemia may be exacerbated by concomitant administration of high doses of calcium-containing preparations, thiazide diuretics, or other vitamin D compounds [see Drug Interactions ( 7 )].

Examples Calcium-containing products, other vitamin D compounds or thiazide diuretics Intervention Monitor serum calcium concentrations more frequently and adjust doxercalciferol dose as needed [see Warnings and Precautions ( 5.1 )].

Thiazide diuretics are known to induce hypercalcemia by reducing excretion of calcium in the urine.