التداخل بين إيفافيرينز وفيراباميل

CYP3A4 inducers decrease verapamil levels ( 7.1 )

Inducers of CYP3A4 (e.g., rifampin) have caused a lowering of plasma levels of verapamil.

Calcium channel blockers: Diltiazem Others (e.g., felodipine, nicardipine, nifedipine, verapamil) ↓ diltiazem * ↓ desacetyl diltiazem * ↓ N-monodesmethyl diltiazem * ↓ calcium channel blocker Diltiazem dose adjustments should be guided by clinical response (refer to the full prescribing information for diltiazem).

When coadministered with efavirenz, dosage adjustment of calcium channels blocker may be needed and should be guided by clinical response (refer to the full prescribing information for the calcium channel blocker).