التداخل بين إليكساكافتور وتيزاكافتور وإيفاكافتور وميدروكسي بروجستيرون

For patients with CF taking hormonal contraceptives who develop rash, consider interrupting TRIKAFTA and hormonal contraceptives.

Following the resolution of rash, consider resuming TRIKAFTA without the hormonal contraceptives.

If rash does not recur, resumption of hormonal contraceptives can be considered.

Hormonal contraceptives may play a role in the occurrence of rash and cannot be excluded [see Adverse Reactions (6.1) ] .

Hormonal Contraceptives TRIKAFTA has been studied with ethinyl estradiol/levonorgestrel and was found to have no clinically relevant effect on the exposures of the oral contraceptive.