التداخل بين إيفيروليموس وأولوباتادين وموميتازون

Concomitant administration of CYP3A4 inhibitors may inhibit the metabolism of, and increase the mometasone furoate plasma concentration and potentially increase the risk for adverse reactions.

Caution should be exercised when considering the coadministration of RYALTRIS with strong CYP3A4 inhibitors [see Clinical Pharmacology ( 12.3 )] .

Inhibitors of Cytochrome P450 3A4 Studies have shown that mometasone furoate, a component of RYALTRIS, is primarily and extensively metabolized to multiple metabolites.

Corticosteroids may be indicated until clinical symptoms resolve.

Administer prophylaxis for PJP when concomitant use of corticosteroids or other immunosuppressive agents are required.