التداخل بين فولفيسترانت وليفوثيروكسين وليوثيرونين

Estrogen, Oral Contraceptives — Estrogens tend to increase serum thyroxine-binding globulin (TBg).

In a patient with a nonfunctioning thyroid gland who is receiving thyroid replacement therapy, free levothyroxine may be decreased when estrogens are started thus increasing thyroid requirements.

Therefore, patients without a functioning thyroid gland who are on thyroid replacement therapy may need to increase their thyroid dose if estrogens or estrogen-containing oral contraceptives are given.