التداخل بين غليبنكلاميد وميتفورمين وأوكسابروزين

Intervention: During concomitant use of OXAPROZIN CAPSULES and glyburide, monitor patient's blood glucose in the beginning phase of cotherapy.

Glyburide Clinical Impact: While oxaprozin does alter the pharmacokinetics of glyburide, coadministration of oxaprozin to type II non-insulin dependent diabetic patients did not affect the area under the glucose concentration curve nor the magnitude or duration of control.

Examples: Nonsteroidal anti-inflammatory agents and other highly protein-boind drugs, salicylcates, sulfonamides, chloramphenicol, probenecid, coumarins, monoamine oxidase inhibitors, beta-adrenergic blocking agents; potentially with ciprofloxacin, micronazole.