التداخل بين هيدروكورتيزون وكيتورولاك

Concurrent administration of corticosteroids with non-steroidal anti-inflammatory drugs (NSAIDS) may increase the risk of gastrointestinal adverse reactions.

Monitor patients receiving corticosteroids and concomitant NSAIDS for gastrointestinal adverse reactions [see Drug Interactions ( 7 )] .

Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Clinical Impact: Concomitant use of NSAIDs and corticosteroids increases the risk of gastrointestinal adverse reactions.

Intervention: Monitor patients receiving ALKINDI SPRINKLE and concomitant NSAIDs.

NSAIDs: concomitant administration increases risk of gastrointestinal adverse reactions.

In addition to past history of ulcer disease, other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids, or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status.

PRECAUTIONS General Ketorolac tromethamine cannot be expected to substitute for corticosteroids or to treat corticosteroid insufficiency.

Patients on prolonged corticosteroid therapy should have their therapy tapered slowly if a decision is made to discontinue corticosteroids.

Abrupt discontinuation of corticosteroids may lead to disease exacerbation.