التداخل بين إيزوسوربيد أحادي النترات وتادالافيل

Do not use isosorbide mononitrate in patients who are taking certain drugs for erectile dysfunction (phosphodiesterase inhibitors), such as sildenafil, tadalafil, or vardenafil.

Drug Interactions Concomitant use of isosorbide mononitrate with phosphodiesterase inhibitors in any form is contraindicated (see CONTRAINDICATIONS).

Administration of CIALIS to patients using any form of organic nitrate is contraindicated.

CIALIS was shown to potentiate the hypotensive effect of nitrates ( 4.1 ).

Nitrates Administration of CIALIS to patients who are using any form of organic nitrate, either regularly and/or intermittently, is contraindicated.

In clinical pharmacology studies, CIALIS was shown to potentiate the hypotensive effect of nitrates [see Clinical Pharmacology ( 12.2 )] .

In such a patient, who has taken CIALIS, where nitrate administration is deemed medically necessary for a life-threatening situation, at least 48 hours should have elapsed after the last dose of CIALIS before nitrate administration is considered.