التداخل بين ليفوسالبوتامول وميتوبرولول وهيدروكلوروثيازيد

In this setting, cardioselective beta-blockers should be considered, although they should be administered with caution.

Diuretics The ECG changes or hypokalemia that may result from the administration of non-potassium-sparing diuretics (such as loop and thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded.

Although the clinical significance of these effects is not known, caution is advised in the coadministration of beta-agonists with non-potassium-sparing diuretics.

Beta-blockers : May block bronchodilatory effects of beta-agonists and produce severe bronchospasm.

Patients with asthma should not normally be treated with beta-blockers.

Because beta1-selectivity is not absolute, use the lowest possible dose of metoprolol tartrate and have bronchodilators (e.g., beta 2 -agonists) readily available or administered concomitantly .