التداخل بين ليفونورجيستريل وإيثينيل إستراديول وميثيمازول

The dose of replacement thyroid hormone or cortisol therapy may need to be increased.

Thyroid Hormone Replacement Therapy or Corticosteroid Replacement Therapy Clinical effect Concomitant use of CHCs with thyroid hormone replacement therapy or corticosteroid replacement therapy may increase systemic exposure of thyroid-binding and cortisol-binding globulin [see Warnings and Precautions (5.11) ].

Prevention or management The dose of replacement thyroid hormone or cortisol therapy may need to be increased.