التداخل بين ليثيوم وميتوبرولول وهيدروكلوروثيازيد

• Diuretics, NSAID, renin-angiotensin system antagonists, or metronidazole may increase lithium serum concentrations.

Drugs Having Clinically Important Interactions with Lithium Table 4: Clinically Important Drug Interactions with Lithium Diuretics Clinical Impact: Diuretic-induced sodium loss may reduce lithium clearance and increase serum lithium concentrations .

Lithium: Risk of lithium toxicity.

Lithium : Diuretics reduce the renal clearance of lithium and increase the risk of lithium toxicity.

Monitor serum lithium concentrations during concurrent use.