التداخل بين لوفيكسيدين وزيبراسيدون

Ziprasidone should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure or conduction abnormalities), cerebrovascular disease, or conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications).

• Because of its potential for inducing hypotension, ziprasidone may enhance the effects of certain antihypertensive agents.

Risk of QT Prolongation : Lofexidine tablets prolong the QT interval.

Increased Risk of CNS Depression with Concomitant use of CNS Depressant Drugs : Lofexidine tablets potentiates the CNS depressant effects of benzodiazepines and may potentiate the CNS depressant effects of alcohol, barbiturates, and other sedating drugs.

Risk of QT Prolongation Lofexidine tablets prolong the QT interval.

Increased Risk of Central Nervous System Depression with Concomitant use of CNS Depressant Drugs Lofexidine tablets potentiates the CNS depressive effects of benzodiazepines and can also be expected to potentiate the CNS depressive effects of alcohol, barbiturates, and other sedating drugs.

Methadone : Methadone and Lofexidine tablets both prolong the QT interval.