التداخل بين ميثوهيكسيتال وفينوباربيتال

SEZABY is contraindicated in patients with: acute porphyrias [see Warnings and Precautions (5.8)], or a history of hypersensitivity reaction to phenobarbital or other barbiturates [see Warnings and Precautions (5.7)] Acute porphyrias (4)

Hypersensitivity to phenobarbital or other barbiturates (4)

SEZABY is contraindicated in patients who have experienced hypersensitivity to phenobarbital or other barbiturates.

CNS depressants: Closely monitor for sedation and respiratory depression.

CNS Depressants Closely monitor for signs of sedation and respiratory depression with concomitant use of SEZABY with other CNS depressants, including opioids [see Warnings and Precautions (5.1)] .

Apnea/hypoventilation may be noted during induction, which may impair pulmonary ventilation; the duration of apnea may be longer than that produced by other barbiturate anesthetics.