التداخل بين نوريلجيسترومين وإيثينيل إستراديول ونوريثيستيرون وإيثينيل إستراديول

WARNING: CIGARETTE SMOKING AND SERIOUS CARDIOVASCULAR EVENTS and CONTRAINDICATED IN WOMEN WITH A BMI |GTE 30 kg/m2 • Cigarette Smoking and Serious Cardiovascular Events Cigarette smoking increases the risk of serious cardiovascular events from hormonal contraceptive use.

Cigarette smoking increases the risk of serious cardiovascular events from combination hormonal contraceptive (CHC) use.

…Populations ( 8.6 ) and Clinical Pharmacology ( 12.3 )] ● Undiagnosed abnormal uterine bleeding [see Warnings and Precautions ( 5.9 )] ● Pregnancy, because there is no reason to use hormonal contraceptives during pregnancy [see Warnings and Precautions ( 5.10 ) and Use in Specific Populations ( 8.1 )] ● Current diagnosis of, or history of, breast cancer, which…

Breast cancer or other estrogen- or progestin-sensitive cancer ( 4 )

Consider an alternate contraceptive method for women with uncontrolled dyslipidemia.

Changes in Contraceptive Effectiveness Associated with Co-Administration of Other Products If a woman on hormonal contraceptives takes a drug or herbal product that induces enzymes, including CYP3A4, that metabolize contraceptive hormones, counsel her to use additional contraception or a different method of contraception.