التداخل بين أوفلوكساسين ووارفارين

This may result in a prolonged half-life for some drugs that are also metabolized by this system (e.g., cyclosporine, theophylline/methylxanthines, warfarin) when coadministered with quinolones.

Therefore, if a quinolone antimicrobial is administered concomitantly with warfarin or its derivatives, the prothrombin time or other suitable coagulation test should be closely monitored.

Warfarin Some quinolones have been reported to enhance the effects of the oral anticoagulant warfarin or its derivatives.