التداخل بين أورفينادرين وأسبرين وكافيين وتريامتيرين وهيدروكلوروثيازيد

Caution is advised in administering nonsteroidal anti-inflammatory agents with triamterene and hydrochlorothiazide.

Thiazides have also been shown to increase the paralyzing effect of nondepolarizing muscle relaxants such as tubocurarine (an effect attributed to potassium loss); consequently, caution should be observed in patients undergoing surgery.

Nonsteroidal Anti-Inflammatory Drugs A possible interaction resulting in acute renal failure has been reported in a few patients on triamterene and hydrochlorothiazide when treated with indomethacin, a nonsteroidal anti-inflammatory agent.