التداخل بين بيرامبانيل وفينكريستين

Therefore, the concomitant use of strong CYP3A inhibitors with vincristine sulfate should be avoided.

Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity.

Patients should be frequently monitored for adverse reactions with concomitant use of moderate CYP3A inhibitors (e.g., fluconazole) with vincristine sulfate.