التداخل بين فينيتوين وفينكريستين

The interaction may result from reduced absorption of phenytoin and an increase in the rate of its metabolism and elimination.

Drug Interactions The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity.

Concurrent use of strong CYP3A inducers (e.g., St.