التداخل بين سيمفاستاتين وأوباداسيتينيب

Elevations in LDL cholesterol decreased to pre-treatment levels in response to statin therapy.

IMNM is characterized by proximal muscle weakness and elevated serum creatine kinase that persist despite discontinuation of statin treatment; positive anti-HMG CoA reductase antibody; muscle biopsy showing necrotizing myopathy without significant inflammation; and improvement with immunosuppressive agents.

Treatment with immunosuppressive agents may be required.