التداخل بين تستوستيرون وتريبتوريلين

Tumor Flare: Transient increase in serum testosterone levels can occur within the first few weeks of treatment.

Tumor Flare Initially, triptorelin (TRELSTAR), like other GnRH agonists, causes a transient increase in serum testosterone levels [ see Clinical Pharmacology (12.2) ].

Laboratory Tests Monitor serum levels of testosterone following injection of TRELSTAR.

In the majority of patients, testosterone levels increased above baseline, and then declined thereafter to castrate levels (< 50 ng/dL) within four weeks [see Clinical Studies ( 14 ) and Adverse Reactions ( 6 )] .

Effect on QT/QTc Interval: Androgen deprivation therapy may prolong the QT interval.