Wechselwirkungen von Docetaxel

Docetaxel (Taxotere, Docivyx) hat in den von uns erfassten FDA-Fachinformationen und Faktenblättern 126 dokumentierte Wechselwirkungen: 64 schwerwiegende, 1 mittelschwere, 61 geringfügige und 0, bei denen eine Fachinformation keine relevante Wechselwirkung berichtet. Jeder Eintrag unten zitiert den Satz, auf dem er beruht. Diese Medikamentenseite ist ein Ausgangspunkt, kein Urteil über Ihre persönliche Situation.

Wechselwirkungen laut Fachinformation

Schwerwiegende Wechselwirkungen (64)

  • AlkoholAlkoholSchwerwiegend

    The alcohol content in a dose of Docetaxel Injection may affect the central nervous system and should be taken into account for patients in whom alcohol intake should be avoided or minimized. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • AmiodaronAntiarrhythmikumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • AprepitantCYP3A4-HemmerSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Atazanavirantiretrovirales ArzneimittelSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Azelastin und FluticasonAntihistaminikumSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • BeclometasonKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • BetamethasonKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • BudesonidKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Budesonid und FormoterolKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • CenobamatAntiepileptikumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • CiclesonidKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • CiclosporinImmunsuppressivumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • CimetidinH2-BlockerSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • ClarithromycinMakrolid-AntibiotikumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • ClobetasolKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Darunavirantiretrovirales ArzneimittelSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Darunavir und Cobicistatantiretrovirales ArzneimittelSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • DeflazacortKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • DesonidKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • DexamethasonKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions have been reported in patients despite dexamethasone premedication. (Fachinformation zu Docetaxel, Boxed Warning (umrahmter Warnhinweis))

  • DiltiazemCalciumkanalblockerSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • DronedaronAntiarrhythmikumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Efavirenzantiretrovirales ArzneimittelSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Efavirenz, Lamivudin und Tenofovirantiretrovirales ArzneimittelSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Elvitegravir, Cobicistat, Emtricitabin und Tenofovirantiretrovirales ArzneimittelSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • ErythromycinMakrolid-AntibiotikumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • EverolimusImmunsuppressivumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • FluconazolAzol-AntimykotikumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • FludrocortisonKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • FlunisolidKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • FluocinonidKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • FluticasonKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Fluticason und SalmeterolKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Fosamprenavirantiretrovirales ArzneimittelSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • FosaprepitantCYP3A4-HemmerSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • HalobetasolKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • HydrocortisonKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • ImatinibCYP3A4-HemmerSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • IsoniazidAntibiotikumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • ItraconazolAzol-AntimykotikumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • IvacaftorCYP3A4-HemmerSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • KetoconazolAzol-AntimykotikumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Lenacapavirantiretrovirales ArzneimittelSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Lopinavir und Ritonavirantiretrovirales ArzneimittelSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • MethylprednisolonKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • MifepristonCYP3A4-HemmerSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • MirabegronBeta-Adrenozeptor-AgonistSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • MometasonKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • NefazodonAntidepressivumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Nirmatrelvir und RitonavirVirostatikumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Olopatadin und MometasonAntihistaminikumSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • PaclitaxelSchwerwiegend

    Patients who have previously experienced a hypersensitivity reaction to paclitaxel may develop a hypersensitivity reaction to docetaxel that may include severe or fatal reactions such as anaphylaxis. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • PalbociclibCYP3A4-HemmerSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • PerampanelAntiepileptikumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • PosaconazolAzol-AntimykotikumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • PrednisolonKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • PrednisonKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • RanolazinQT-verlängerndes ArzneimittelSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Ritonavirantiretrovirales ArzneimittelSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • SuvorexantSchlaf- und BeruhigungsmittelSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • TicagrelorThrombozytenaggregationshemmerSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • TriamcinolonKortikosteroidSchwerwiegend

    Severe hypersensitivity reactions characterized by generalized rash/erythema, hypotension and/or bronchospasm, or fatal anaphylaxis, have been reported in patients premedicated with 3 days of corticosteroids. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • VerapamilCalciumkanalblockerSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • VoriconazolAzol-AntimykotikumSchwerwiegend

    Concomitant use of Docetaxel Injection and drugs that inhibit CYP3A4 may increase exposure to docetaxel and should be avoided. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

Mittelschwere Wechselwirkungen (1)

  • TrastuzumabMittelschwer

    In BCIRG006, a total of 2.9% (31/1056) of patients in the TCH (docetaxel, carboplatin, trastuzumab) arm (1.5% during the chemotherapy phase and 1.4% during the monotherapy phase) and 5.7% (61/1068) of patients in the AC-TH arm (1.5% during the chemotherapy phase and 4.2% during the monotherapy phase) discontinued trastuzumab due to cardiac toxicity. (Fachinformation zu Trastuzumab, Warnhinweise und Vorsichtsmaßnahmen)

Geringfügige Erwähnungen (61)

  • AcetazolamidCarboanhydrasehemmerGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Amiloridkaliumsparendes DiuretikumGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • ArmodafinilZNS-StimulansGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Atenolol und ChlortalidonBetablockerGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Benazepril und HydrochlorothiazidACE-HemmerGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Bisoprolol und HydrochlorothiazidBetablockerGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • BosentanCYP3A4-InduktorGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • BumetanidSchleifendiuretikumGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Candesartan und HydrochlorothiazidAngiotensin-II-Rezeptorblocker (Sartan)Geringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • CapecitabinAntimetabolitGeringfügig

    In the 251 patients with metastatic breast cancer who received XELODA with docetaxel, 68% had grade 3 or 4 neutropenia, 2.8% had grade 3 or 4 thrombocytopenia, and 10% had grade 3 or 4 anemia. (Fachinformation zu Capecitabin, Warnhinweise und Vorsichtsmaßnahmen)

  • CarbamazepinAntiepileptikumGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • ChlorothiazidThiaziddiuretikumGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • ChlortalidonThiaziddiuretikumGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • CisplatinGeringfügig

    In gastric cancer patients treated with docetaxel in combination with cisplatin and fluorouracil (TCF), febrile neutropenia and/or neutropenic infection occurred in 12% of patients receiving G-CSF compared to 28% who did not. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • ClobazamBenzodiazepinGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • CyclophosphamidImmunsuppressivumGeringfügig

    Treatment-related AML or MDS has occurred in patients given anthracyclines and/or cyclophosphamide, including use in adjuvant therapy for breast cancer. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • DeferasiroxEisenpräparatGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • DoxorubicinGeringfügig

    In the adjuvant breast cancer trial (TAX316) AML occurred in 3 of 744 patients who received docetaxel, doxorubicin, and cyclophosphamide (TAC) and in 1 of 736 patients who received fluorouracil, doxorubicin, and cyclophosphamide [ see Clinical Studies (14.2) ]. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Enalapril und HydrochlorothiazidACE-HemmerGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • EplerenonAldosteronantagonistGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • EslicarbazepinAntiepileptikumGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • EtacrynsäureSchleifendiuretikumGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Etravirinantiretrovirales ArzneimittelGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • FluorouracilAntimetabolitGeringfügig

    In gastric cancer patients treated with docetaxel in combination with cisplatin and fluorouracil (TCF), febrile neutropenia and/or neutropenic infection occurred in 12% of patients receiving G-CSF compared to 28% who did not. (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Fosinopril und HydrochlorothiazidACE-HemmerGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • FosphenytoinAntiepileptikumGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • FurosemidSchleifendiuretikumGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • GriseofulvinAntimykotikumGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • HydrochlorothiazidThiaziddiuretikumGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • IndapamidThiaziddiuretikumGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Irbesartan und HydrochlorothiazidAngiotensin-II-Rezeptorblocker (Sartan)Geringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Lisinopril und HydrochlorothiazidACE-HemmerGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • LorlatinibCYP3A4-InduktorGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Losartan und HydrochlorothiazidAngiotensin-II-Rezeptorblocker (Sartan)Geringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • MetolazonThiaziddiuretikumGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Metoprolol und HydrochlorothiazidBetablockerGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • MitapivatCYP3A4-InduktorGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • MitotanCYP3A4-InduktorGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • ModafinilZNS-StimulansGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • NafcillinPenicillin-AntibiotikumGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Nevirapinantiretrovirales ArzneimittelGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Olmesartan und HydrochlorothiazidAngiotensin-II-Rezeptorblocker (Sartan)Geringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Olmesartan, Amlodipin und HydrochlorothiazidAngiotensin-II-Rezeptorblocker (Sartan)Geringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • OxcarbazepinAntiepileptikumGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • PhenobarbitalBarbituratGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Phentermin und TopiramatZNS-StimulansGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • PhenytoinAntiepileptikumGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • PrimidonAntiepileptikumGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Quinapril und HydrochlorothiazidACE-HemmerGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • RifabutinAntibiotikumGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • RifampicinAntibiotikumGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • RifapentinAntibiotikumGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • SpironolactonAldosteronantagonistGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Spironolacton und HydrochlorothiazidAldosteronantagonistGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • SuzetriginCYP3A4-InduktorGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • Telmisartan und HydrochlorothiazidAngiotensin-II-Rezeptorblocker (Sartan)Geringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • TopiramatAntiepileptikumGeringfügig

    • Cytochrome P450 3A4 inducers, inhibitors, or substrates: May alter docetaxel metabolism. (Fachinformation zu Docetaxel, Arzneimittelwechselwirkungen)

  • TorasemidSchleifendiuretikumGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Triamterenkaliumsparendes DiuretikumGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Triamteren und Hydrochlorothiazidkaliumsparendes DiuretikumGeringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

  • Valsartan und HydrochlorothiazidAngiotensin-II-Rezeptorblocker (Sartan)Geringfügig

    Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (Fachinformation zu Docetaxel, Warnhinweise und Vorsichtsmaßnahmen)

Prüfen Sie Docetaxel gegen alles, was Sie einnehmen. Fügen Sie Ihre gesamte Liste hinzu; alle Paare werden auf einmal geprüft.

Im Wechselwirkungscheck öffnen

Keine medizinische Beratung. Der Schweregrad gibt die Formulierung der Fachinformation wieder, nicht Ihre persönlichen Umstände. Eine als „schwerwiegend“ eingestufte Wechselwirkung kann unter Aufsicht Routine sein, und eine „geringfügige“ kann bei hohen Dosen von Bedeutung sein. Fragen Sie in einer Apotheke nach.