Wechselwirkungen von IncobotulinumtoxinA

IncobotulinumtoxinA (Xeomin), ein neuromuskulärer Blocker, hat in den von uns erfassten FDA-Fachinformationen und Faktenblättern 106 dokumentierte Wechselwirkungen: 6 schwerwiegende, 90 mittelschwere, 9 geringfügige und 1, bei denen eine Fachinformation keine relevante Wechselwirkung berichtet. Jeder Eintrag unten zitiert den Satz, auf dem er beruht. Diese Medikamentenseite ist ein Ausgangspunkt, kein Urteil über Ihre persönliche Situation.

Wechselwirkungen laut Fachinformation

Schwerwiegende Wechselwirkungen (6)

  • ChininMalariamittelSchwerwiegend

    Avoid concomitant use with neuromuscular blocking agents. (Fachinformation zu Chinin, Warnhinweise und Vorsichtsmaßnahmen)

  • NeomycinAminoglykosidSchwerwiegend

    The possibility of the occurrence of neuromuscular blockage and respiratory paralysis should be considered if neomycin is administered, especially to patients receiving anesthetics, neuromuscular blocking agents such as tubocurarine, succinylcholine, decamethonium, or in patients receiving massive transfusions of citrate anticoagulated blood. (Fachinformation zu Neomycin, Boxed Warning (umrahmter Warnhinweis))

  • PlazomicinAminoglykosidSchwerwiegend

    During therapy with ZEMDRI, monitor for adverse reactions associated with neuromuscular blockade, particularly in high-risk patients, such as patients with underlying neuromuscular disorders (including myasthenia gravis) or in patients concomitantly receiving neuromuscular blocking agents [see Warning and Precautions (5.3) ] . (Fachinformation zu Plazomicin, Boxed Warning (umrahmter Warnhinweis))

  • RemifentanilOpioidSchwerwiegend

    In the case of life-threatening muscle rigidity, a rapid onset neuromuscular blocker or naloxone may be administered. (Fachinformation zu Remifentanil, Warnhinweise und Vorsichtsmaßnahmen)

  • Rocuroniumneuromuskulärer BlockerSchwerwiegend

    Rocuronium Bromide Injection is contraindicated in patients known to have hypersensitivity (e.g., anaphylaxis) to rocuronium bromide or other neuromuscular blocking agents [see Warnings and Precautions ( 5.2 )] . (Fachinformation zu Rocuronium, Gegenanzeigen)

  • SugammadexSchwerwiegend

    Reversal of Neuromuscular Blocking Agents Other Than Rocuronium or Vecuronium Do not use BRIDION to reverse blockade induced by nonsteroidal neuromuscular blocking agents such as succinylcholine or benzylisoquinolinium compounds. (Fachinformation zu Sugammadex, Warnhinweise und Vorsichtsmaßnahmen)

Mittelschwere Wechselwirkungen (90)

  • AclidiniumbromidAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • AmantadinAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • AmikacinAminoglykosidMittelschwer

    Aminoglycosides or other agents that interfere with neuromuscular transmission may potentiate the effect of XEOMIN; co-administer only with caution and close observation ( 7 ) (Fachinformation zu IncobotulinumtoxinA, Arzneimittelwechselwirkungen)

  • Amitriptylintrizyklisches AntidepressivumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Amoxapintrizyklisches AntidepressivumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Atracuriumneuromuskulärer BlockerMittelschwer

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (Fachinformation zu Atracurium, Warnhinweise)

  • AtropinAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Atropin und PralidoximAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • BaclofenMuskelrelaxansMittelschwer

    Aminoglycosides and Other Agents Interfering with Neuromuscular Transmission Co-administration of XEOMIN and aminoglycosides or other agents interfering with neuromuscular transmission (e.g., tubocurarine-type muscle relaxants) should only be performed with caution as these agents may potentiate the effect of the toxin. (Fachinformation zu IncobotulinumtoxinA, Arzneimittelwechselwirkungen)

  • Belladonna und OpiumOpioidMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • BenzatropinAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • CarbinoxaminAntihistaminikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • CarisoprodolMuskelrelaxansMittelschwer

    Aminoglycosides and Other Agents Interfering with Neuromuscular Transmission Co-administration of XEOMIN and aminoglycosides or other agents interfering with neuromuscular transmission (e.g., tubocurarine-type muscle relaxants) should only be performed with caution as these agents may potentiate the effect of the toxin. (Fachinformation zu IncobotulinumtoxinA, Arzneimittelwechselwirkungen)

  • ChinidinAntiarrhythmikumMittelschwer

    Quinidine potentiates the actions of depolarizing (succinylcholine, decamethonium) and non-depolarizing ( d -tubocurarine, pancuronium) neuromuscular blocking agents . (Fachinformation zu Chinidin, Arzneimittelwechselwirkungen)

  • Chlordiazepoxid und ClidiniumbromidBenzodiazepinMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • ChlorphenaminAntihistaminikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • ChlorpromazinAntipsychotikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • ChlorzoxazonMuskelrelaxansMittelschwer

    Aminoglycosides and Other Agents Interfering with Neuromuscular Transmission Co-administration of XEOMIN and aminoglycosides or other agents interfering with neuromuscular transmission (e.g., tubocurarine-type muscle relaxants) should only be performed with caution as these agents may potentiate the effect of the toxin. (Fachinformation zu IncobotulinumtoxinA, Arzneimittelwechselwirkungen)

  • Cisatracuriumneuromuskulärer BlockerMittelschwer

    Precautions should also be taken in those patients who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported. (Fachinformation zu Cisatracurium, Warnhinweise und Vorsichtsmaßnahmen)

  • ClemastinAntihistaminikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • ClindamycinAntibiotikumMittelschwer

    • Neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. (Fachinformation zu Clindamycin, Arzneimittelwechselwirkungen)

  • Clomipramintrizyklisches AntidepressivumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • ClozapinAntipsychotikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • CyclobenzaprinMuskelrelaxansMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • CyclopentolatAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • CyproheptadinAntihistaminikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • DantrolenMuskelrelaxansMittelschwer

    Aminoglycosides and Other Agents Interfering with Neuromuscular Transmission Co-administration of XEOMIN and aminoglycosides or other agents interfering with neuromuscular transmission (e.g., tubocurarine-type muscle relaxants) should only be performed with caution as these agents may potentiate the effect of the toxin. (Fachinformation zu IncobotulinumtoxinA, Arzneimittelwechselwirkungen)

  • DarifenacinAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • DeflazacortKortikosteroidMittelschwer

    Myopathy Patients receiving corticosteroids, including EMFLAZA, and concomitant therapy with neuromuscular blocking agents (e.g., pancuronium) or patients with disorders of neuromuscular transmission (e.g., myasthenia gravis) may be at increased risk of developing acute myopathy. (Fachinformation zu Deflazacort, Warnhinweise und Vorsichtsmaßnahmen)

  • DesfluranAllgemeinanästhetikumMittelschwer

    Neuromuscular Blocking Agents Anesthetic concentrations of desflurane at equilibrium (administered for 15 or more minutes before testing) reduced the ED 95 of succinylcholine by approximately 30% and that of atracurium and pancuronium by approximately 50% compared to N 2 O/opioid anesthesia (see Table 4). (Fachinformation zu Desfluran, Arzneimittelwechselwirkungen)

  • Desipramintrizyklisches AntidepressivumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • DexchlorpheniraminAntihistaminikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • DicycloverinAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • DimenhydrinatAntihistaminikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • DiphenhydraminAntihistaminikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • DisopyramidAntiarrhythmikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Doxepintrizyklisches AntidepressivumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • DoxylaminAntihistaminikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Doxylamin und PyridoxinAntihistaminikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • FentanylOpioidMittelschwer

    • Risks of Skeletal Muscle Rigidity and Skeletal Muscle Movement : Manage with neuromuscular blocking agent. (Fachinformation zu Fentanyl, Warnhinweise und Vorsichtsmaßnahmen)

  • FesoterodinAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • FlavoxatAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • GentamicinAminoglykosidMittelschwer

    Aminoglycosides or other agents that interfere with neuromuscular transmission may potentiate the effect of XEOMIN; co-administer only with caution and close observation ( 7 ) (Fachinformation zu IncobotulinumtoxinA, Arzneimittelwechselwirkungen)

  • GlycopyrroniumbromidAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • HydroxyzinAntihistaminikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • HyoscyaminAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Imipramintrizyklisches AntidepressivumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • IpratropiumbromidAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Ipratropiumbromid und SalbutamolAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • IsofluranAllgemeinanästhetikumMittelschwer

    • FORANE decreases the doses of neuromuscular blocking agents required. (Fachinformation zu Isofluran, Arzneimittelwechselwirkungen)

  • LincomycinAntibiotikumMittelschwer

    Drug Interactions Lincomycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents; therefore, it should be used with caution in patients receiving such agents. (Fachinformation zu Lincomycin, Arzneimittelwechselwirkungen)

  • Lithiumserotonerges ArzneimittelMittelschwer

    Neuromuscular Blocking Agents Clinical Impact: Lithium may prolong the effects of neuromuscular blocking agents. (Fachinformation zu Lithium, Arzneimittelwechselwirkungen)

  • MeclozinAntihistaminikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • MetaxalonMuskelrelaxansMittelschwer

    Aminoglycosides and Other Agents Interfering with Neuromuscular Transmission Co-administration of XEOMIN and aminoglycosides or other agents interfering with neuromuscular transmission (e.g., tubocurarine-type muscle relaxants) should only be performed with caution as these agents may potentiate the effect of the toxin. (Fachinformation zu IncobotulinumtoxinA, Arzneimittelwechselwirkungen)

  • MethocarbamolMuskelrelaxansMittelschwer

    Aminoglycosides and Other Agents Interfering with Neuromuscular Transmission Co-administration of XEOMIN and aminoglycosides or other agents interfering with neuromuscular transmission (e.g., tubocurarine-type muscle relaxants) should only be performed with caution as these agents may potentiate the effect of the toxin. (Fachinformation zu IncobotulinumtoxinA, Arzneimittelwechselwirkungen)

  • MethylscopolaminAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Nortriptylintrizyklisches AntidepressivumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • OlanzapinAntipsychotikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Olanzapin und FluoxetinAntipsychotikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • OrphenadrinMuskelrelaxansMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • OxybutyninAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • ParoxetinSSRIMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Piperacillin und TazobactamPenicillin-AntibiotikumMittelschwer

    Piperacillin and Tazobactam for Injection and Sodium Chloride Injection may prolong the neuromuscular blockade of vecuronium and other non-depolarizing neuromuscular blockers. (Fachinformation zu Piperacillin und Tazobactam, Arzneimittelwechselwirkungen)

  • ProcainamidAntiarrhythmikumMittelschwer

    Patients taking PA who require neuromuscular blocking agents such as succinylcholine may require less than usual doses of the latter, due to PA effects on reducing acetylcholine release. (Fachinformation zu Procainamid, Arzneimittelwechselwirkungen)

  • ProchlorperazinAntipsychotikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • PromethazinAntihistaminikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Promethazin und CodeinOpioidMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Promethazin und DextromethorphanAntihistaminikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Protriptylintrizyklisches AntidepressivumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • PyridostigminCholinesterasehemmerMittelschwer

    Depolarizing neuromuscular blocking agents: Increased effect. (Fachinformation zu Pyridostigmin, Arzneimittelwechselwirkungen)

  • ScopolaminAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • SevofluranAllgemeinanästhetikumMittelschwer

    Neuromuscular Blocking Agents As is the case with other volatile anesthetics, sevoflurane increases both the intensity and duration of neuromuscular blockade induced by nondepolarizing muscle relaxants. (Fachinformation zu Sevofluran, Arzneimittelwechselwirkungen)

  • SolifenacinAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Suxamethoniumneuromuskulärer BlockerMittelschwer

    If other neuromuscular blocking agents are to be used during the same procedure, consider the possibility of a synergistic or antagonistic effect. (Fachinformation zu Suxamethonium, Arzneimittelwechselwirkungen)

  • ThioridazinAntipsychotikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • TiotropiumbromidAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • TizanidinMuskelrelaxansMittelschwer

    Aminoglycosides and Other Agents Interfering with Neuromuscular Transmission Co-administration of XEOMIN and aminoglycosides or other agents interfering with neuromuscular transmission (e.g., tubocurarine-type muscle relaxants) should only be performed with caution as these agents may potentiate the effect of the toxin. (Fachinformation zu IncobotulinumtoxinA, Arzneimittelwechselwirkungen)

  • TobramycinAminoglykosidMittelschwer

    Aminoglycosides or other agents that interfere with neuromuscular transmission may potentiate the effect of XEOMIN; co-administer only with caution and close observation ( 7 ) (Fachinformation zu IncobotulinumtoxinA, Arzneimittelwechselwirkungen)

  • TolterodinAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • TrihexyphenidylAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Trimipramintrizyklisches AntidepressivumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • TrospiumchloridAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • UmeclidiniumbromidAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Umeclidiniumbromid und VilanterolAnticholinergikumMittelschwer

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (Fachinformation zu IncobotulinumtoxinA, Warnhinweise und Vorsichtsmaßnahmen)

  • Vecuroniumneuromuskulärer BlockerMittelschwer

    Precautions should also be taken in those individuals who have had previous anaphylactic reactions to other neuromuscular blocking agents since cross-reactivity between neuromuscular blocking agents, both depolarizing and non-depolarizing, has been reported in this class of drugs. (Fachinformation zu Vecuronium, Warnhinweise)

  • VerapamilCalciumkanalblockerMittelschwer

    Neuromuscular Blocking Agents Clinical data and animal studies suggest that verapamil may potentiate the activity of neuromuscular blocking agents (curare-like and depolarizing). (Fachinformation zu Verapamil, Arzneimittelwechselwirkungen)

Geringfügige Erwähnungen (9)

  • CarbamazepinAntiepileptikumGeringfügig

    N e uromuscular Blocking Agents Resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents pancuronium, vecuronium, rocuronium and cisatracurium has occurred in patients chronically administered carbamazepine. (Fachinformation zu Carbamazepin, Arzneimittelwechselwirkungen)

  • DigoxinDigitalisglykosidGeringfügig

    Norepinephrine Dopamine Neuromuscular Blocking Agents Succinylcholine May cause sudden extrusion of potassium from muscle cells causing arrhythmias in patients taking digoxin. (Fachinformation zu Digoxin, Arzneimittelwechselwirkungen)

  • DonepezilCholinesterasehemmerGeringfügig

    A synergistic effect may be expected with concomitant administration of succinylcholine, similar neuromuscular blocking agents, or cholinergic agonists ( 7.2 ) (Fachinformation zu Donepezil, Arzneimittelwechselwirkungen)

  • DoxapramGeringfügig

    In patients who have received neuromuscular blocking agents, doxapram may temporarily mask the residual effects of these drugs. (Fachinformation zu Doxapram, Arzneimittelwechselwirkungen)

  • FosphenytoinAntiepileptikumGeringfügig

    Neuromuscular blocking agents Cisatracurium, pancuronium, rocuronium and vecuronium: resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents has occurred in patients chronically administered phenytoin. (Fachinformation zu Fosphenytoin, Arzneimittelwechselwirkungen)

  • GalantaminCholinesterasehemmerGeringfügig

    Anesthesia Galantamine, as a cholinesterase inhibitor, is likely to exaggerate the neuromuscular blocking effects of succinylcholine-type and similar neuromuscular blocking agents during anesthesia. (Fachinformation zu Galantamin, Warnhinweise und Vorsichtsmaßnahmen)

  • Memantin und DonepezilCholinesterasehemmerGeringfügig

    Concomitant administration of succinylcholine, similar neuromuscular blocking agents, or cholinergic agonists may lead to synergistic effect. (Fachinformation zu Memantin und Donepezil, Arzneimittelwechselwirkungen)

  • PhenytoinAntiepileptikumGeringfügig

    Neuromuscular blocking agents Cisatracurium, pancuronium, rocuronium and vecuronium: resistance to the neuromuscular blocking action of the nondepolarizing neuromuscular blocking agents has occurred in patients chronically administered phenytoin. (Fachinformation zu Phenytoin, Arzneimittelwechselwirkungen)

  • PropofolZNS-dämpfendes ArzneimittelGeringfügig

    Common Neuromuscular Blocking Agents DIPRIVAN does not cause a clinically significant change in onset, intensity or duration of action of the commonly used neuromuscular blocking agents (e.g., succinylcholine and nondepolarizing muscle relaxants). (Fachinformation zu Propofol, Arzneimittelwechselwirkungen)

Keine relevante Wechselwirkung berichtet (1)

  • DexmedetomidinAlpha-Adrenozeptor-AgonistKeine Wechselwirkung

    Neuromuscular Blockers In one study of 10 healthy adult volunteers, administration of PRECEDEX for 45 minutes at a plasma concentration of one ng/mL resulted in no clinically meaningful increases in the magnitude of neuromuscular blockade associated with rocuronium administration. (Fachinformation zu Dexmedetomidin, Arzneimittelwechselwirkungen)

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