Wechselwirkungen von Pomalidomid

Pomalidomid (Pomalyst) hat in den von uns erfassten FDA-Fachinformationen und Faktenblättern 29 dokumentierte Wechselwirkungen: 9 schwerwiegende, 20 mittelschwere, 0 geringfügige und 0, bei denen eine Fachinformation keine relevante Wechselwirkung berichtet. Jeder Eintrag unten zitiert den Satz, auf dem er beruht. Diese Medikamentenseite ist ein Ausgangspunkt, kein Urteil über Ihre persönliche Situation.

Wechselwirkungen laut Fachinformation

Schwerwiegende Wechselwirkungen (9)

  • Cannabidiol (verschreibungspflichtig)AntiepileptikumSchwerwiegend

    Strong CYP1A2 Inhibitors: Avoid concomitant use of strong CYP1A2 inhibitors. (Fachinformation zu Pomalidomid, Arzneimittelwechselwirkungen)

  • CimetidinH2-BlockerSchwerwiegend

    Strong CYP1A2 Inhibitors: Avoid concomitant use of strong CYP1A2 inhibitors. (Fachinformation zu Pomalidomid, Arzneimittelwechselwirkungen)

  • CiprofloxacinFluorchinolonSchwerwiegend

    Strong CYP1A2 Inhibitors: Avoid concomitant use of strong CYP1A2 inhibitors. (Fachinformation zu Pomalidomid, Arzneimittelwechselwirkungen)

  • DeferasiroxEisenpräparatSchwerwiegend

    Strong CYP1A2 Inhibitors: Avoid concomitant use of strong CYP1A2 inhibitors. (Fachinformation zu Pomalidomid, Arzneimittelwechselwirkungen)

  • DexamethasonKortikosteroidSchwerwiegend

    Treatment of patients with MM with a PD-1 or PD-L1 blocking antibody in combination with a thalidomide analogue plus dexamethasone is not recommended outside of controlled clinical trials. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • FluvoxaminSSRISchwerwiegend

    Strong CYP1A2 Inhibitors: Avoid concomitant use of strong CYP1A2 inhibitors. (Fachinformation zu Pomalidomid, Arzneimittelwechselwirkungen)

  • MexiletinAntiarrhythmikumSchwerwiegend

    Strong CYP1A2 Inhibitors: Avoid concomitant use of strong CYP1A2 inhibitors. (Fachinformation zu Pomalidomid, Arzneimittelwechselwirkungen)

  • ViloxazinNoradrenalin-WiederaufnahmehemmerSchwerwiegend

    Strong CYP1A2 Inhibitors: Avoid concomitant use of strong CYP1A2 inhibitors. (Fachinformation zu Pomalidomid, Arzneimittelwechselwirkungen)

  • ZileutonCYP1A2-HemmerSchwerwiegend

    Strong CYP1A2 Inhibitors: Avoid concomitant use of strong CYP1A2 inhibitors. (Fachinformation zu Pomalidomid, Arzneimittelwechselwirkungen)

Mittelschwere Wechselwirkungen (20)

  • ApixabanAntikoagulans (Gerinnungshemmer)Mittelschwer

    In Trial 2, where anticoagulant therapies were mandated, thromboembolic events occurred in 8.0% of patients treated with POMALYST and low dose-dexamethasone (Low-dose Dex), and 3.3% of patients treated with high-dose dexamethasone. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • ArgatrobanAntikoagulans (Gerinnungshemmer)Mittelschwer

    In Trial 2, where anticoagulant therapies were mandated, thromboembolic events occurred in 8.0% of patients treated with POMALYST and low dose-dexamethasone (Low-dose Dex), and 3.3% of patients treated with high-dose dexamethasone. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • BivalirudinAntikoagulans (Gerinnungshemmer)Mittelschwer

    In Trial 2, where anticoagulant therapies were mandated, thromboembolic events occurred in 8.0% of patients treated with POMALYST and low dose-dexamethasone (Low-dose Dex), and 3.3% of patients treated with high-dose dexamethasone. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • DabigatranAntikoagulans (Gerinnungshemmer)Mittelschwer

    In Trial 2, where anticoagulant therapies were mandated, thromboembolic events occurred in 8.0% of patients treated with POMALYST and low dose-dexamethasone (Low-dose Dex), and 3.3% of patients treated with high-dose dexamethasone. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • Desogestrel und Ethinylestradiolorales KontrazeptivumMittelschwer

    Females must commit either to abstain continuously from heterosexual sexual intercourse or to use 2 methods of reliable birth control, beginning 4 weeks prior to initiating treatment with POMALYST, during therapy, during dose interruptions, and continuing for 4 weeks following discontinuation of POMALYST therapy. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • Drospirenon und Ethinylestradiolorales KontrazeptivumMittelschwer

    Females must commit either to abstain continuously from heterosexual sexual intercourse or to use 2 methods of reliable birth control, beginning 4 weeks prior to initiating treatment with POMALYST, during therapy, during dose interruptions, and continuing for 4 weeks following discontinuation of POMALYST therapy. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • EdoxabanAntikoagulans (Gerinnungshemmer)Mittelschwer

    In Trial 2, where anticoagulant therapies were mandated, thromboembolic events occurred in 8.0% of patients treated with POMALYST and low dose-dexamethasone (Low-dose Dex), and 3.3% of patients treated with high-dose dexamethasone. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • EnoxaparinAntikoagulans (Gerinnungshemmer)Mittelschwer

    In Trial 2, where anticoagulant therapies were mandated, thromboembolic events occurred in 8.0% of patients treated with POMALYST and low dose-dexamethasone (Low-dose Dex), and 3.3% of patients treated with high-dose dexamethasone. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • Estradiol und Dienogestorales KontrazeptivumMittelschwer

    Females must commit either to abstain continuously from heterosexual sexual intercourse or to use 2 methods of reliable birth control, beginning 4 weeks prior to initiating treatment with POMALYST, during therapy, during dose interruptions, and continuing for 4 weeks following discontinuation of POMALYST therapy. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • Etynodioldiacetat und Ethinylestradiolorales KontrazeptivumMittelschwer

    Females must commit either to abstain continuously from heterosexual sexual intercourse or to use 2 methods of reliable birth control, beginning 4 weeks prior to initiating treatment with POMALYST, during therapy, during dose interruptions, and continuing for 4 weeks following discontinuation of POMALYST therapy. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • FondaparinuxAntikoagulans (Gerinnungshemmer)Mittelschwer

    In Trial 2, where anticoagulant therapies were mandated, thromboembolic events occurred in 8.0% of patients treated with POMALYST and low dose-dexamethasone (Low-dose Dex), and 3.3% of patients treated with high-dose dexamethasone. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • HeparinAntikoagulans (Gerinnungshemmer)Mittelschwer

    In Trial 2, where anticoagulant therapies were mandated, thromboembolic events occurred in 8.0% of patients treated with POMALYST and low dose-dexamethasone (Low-dose Dex), and 3.3% of patients treated with high-dose dexamethasone. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • Levonorgestrel und Ethinylestradiolorales KontrazeptivumMittelschwer

    Females must commit either to abstain continuously from heterosexual sexual intercourse or to use 2 methods of reliable birth control, beginning 4 weeks prior to initiating treatment with POMALYST, during therapy, during dose interruptions, and continuing for 4 weeks following discontinuation of POMALYST therapy. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • NorethisteronGestagenMittelschwer

    Females must commit either to abstain continuously from heterosexual sexual intercourse or to use 2 methods of reliable birth control, beginning 4 weeks prior to initiating treatment with POMALYST, during therapy, during dose interruptions, and continuing for 4 weeks following discontinuation of POMALYST therapy. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • Norethisteron und Ethinylestradiolorales KontrazeptivumMittelschwer

    Females must commit either to abstain continuously from heterosexual sexual intercourse or to use 2 methods of reliable birth control, beginning 4 weeks prior to initiating treatment with POMALYST, during therapy, during dose interruptions, and continuing for 4 weeks following discontinuation of POMALYST therapy. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • Norgestimat und Ethinylestradiolorales KontrazeptivumMittelschwer

    Females must commit either to abstain continuously from heterosexual sexual intercourse or to use 2 methods of reliable birth control, beginning 4 weeks prior to initiating treatment with POMALYST, during therapy, during dose interruptions, and continuing for 4 weeks following discontinuation of POMALYST therapy. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • Norgestrel und Ethinylestradiolorales KontrazeptivumMittelschwer

    Females must commit either to abstain continuously from heterosexual sexual intercourse or to use 2 methods of reliable birth control, beginning 4 weeks prior to initiating treatment with POMALYST, during therapy, during dose interruptions, and continuing for 4 weeks following discontinuation of POMALYST therapy. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • RivaroxabanAntikoagulans (Gerinnungshemmer)Mittelschwer

    In Trial 2, where anticoagulant therapies were mandated, thromboembolic events occurred in 8.0% of patients treated with POMALYST and low dose-dexamethasone (Low-dose Dex), and 3.3% of patients treated with high-dose dexamethasone. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • Tabak und RauchenTabak und CannabisMittelschwer

    Patients with known risk factors, including prior thrombosis, may be at greater risk, and actions should be taken to try to minimize all modifiable factors (e.g., hyperlipidemia, hypertension, smoking). (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

  • WarfarinAntikoagulans (Gerinnungshemmer)Mittelschwer

    In Trial 2, where anticoagulant therapies were mandated, thromboembolic events occurred in 8.0% of patients treated with POMALYST and low dose-dexamethasone (Low-dose Dex), and 3.3% of patients treated with high-dose dexamethasone. (Fachinformation zu Pomalidomid, Warnhinweise und Vorsichtsmaßnahmen)

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Im Wechselwirkungscheck öffnen

Keine medizinische Beratung. Der Schweregrad gibt die Formulierung der Fachinformation wieder, nicht Ihre persönlichen Umstände. Eine als „schwerwiegend“ eingestufte Wechselwirkung kann unter Aufsicht Routine sein, und eine „geringfügige“ kann bei hohen Dosen von Bedeutung sein. Fragen Sie in einer Apotheke nach.