Interaction Checker

Daptomycin interactions

Daptomycin (Cubicin), an antibiotic has 32 documented interactions across the FDA labels and fact sheets we index: 0 major, 32 moderate, 0 minor, and 0 where a label reports no significant interaction. Each entry below quotes the sentence behind it. This drug page is a starting point, not a verdict for your situation.

Interactions from the label

Moderate interactions (32)

  • Amlodipine and atorvastatindihydropyridine calcium channel blockerModerate

    In patients who receive Daptomycin for Injection, CPK levels should be monitored weekly, and more frequently in patients who received recent prior or concomitant therapy with an HMG-CoA reductase inhibitor or in whom elevations in CPK occur during treatment with Daptomycin for Injection. (Daptomycin label, Warnings and precautions)

  • AtorvastatinstatinModerate

    In patients who receive Daptomycin for Injection, CPK levels should be monitored weekly, and more frequently in patients who received recent prior or concomitant therapy with an HMG-CoA reductase inhibitor or in whom elevations in CPK occur during treatment with Daptomycin for Injection. (Daptomycin label, Warnings and precautions)

  • Azelastine and fluticasoneantihistamineModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • BeclomethasonecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • BetamethasonecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • BudesonidecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • Budesonide and formoterolcorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • CiclesonidecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • ClobetasolcorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • DeflazacortcorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • DesonidecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • DexamethasonecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • Ezetimibe and simvastatinstatinModerate

    In patients who receive Daptomycin for Injection, CPK levels should be monitored weekly, and more frequently in patients who received recent prior or concomitant therapy with an HMG-CoA reductase inhibitor or in whom elevations in CPK occur during treatment with Daptomycin for Injection. (Daptomycin label, Warnings and precautions)

  • FludrocortisonecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • FlunisolidecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • FluocinonidecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • FluticasonecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • Fluticasone and salmeterolcorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • FluvastatinstatinModerate

    In patients who receive Daptomycin for Injection, CPK levels should be monitored weekly, and more frequently in patients who received recent prior or concomitant therapy with an HMG-CoA reductase inhibitor or in whom elevations in CPK occur during treatment with Daptomycin for Injection. (Daptomycin label, Warnings and precautions)

  • HalobetasolcorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • HydrocortisonecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • LovastatinstatinModerate

    In patients who receive Daptomycin for Injection, CPK levels should be monitored weekly, and more frequently in patients who received recent prior or concomitant therapy with an HMG-CoA reductase inhibitor or in whom elevations in CPK occur during treatment with Daptomycin for Injection. (Daptomycin label, Warnings and precautions)

  • MethylprednisolonecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • MometasonecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • Olopatadine and mometasoneantihistamineModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • PitavastatinstatinModerate

    In patients who receive Daptomycin for Injection, CPK levels should be monitored weekly, and more frequently in patients who received recent prior or concomitant therapy with an HMG-CoA reductase inhibitor or in whom elevations in CPK occur during treatment with Daptomycin for Injection. (Daptomycin label, Warnings and precautions)

  • PravastatinstatinModerate

    In patients who receive Daptomycin for Injection, CPK levels should be monitored weekly, and more frequently in patients who received recent prior or concomitant therapy with an HMG-CoA reductase inhibitor or in whom elevations in CPK occur during treatment with Daptomycin for Injection. (Daptomycin label, Warnings and precautions)

  • PrednisolonecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • PrednisonecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

  • RosuvastatinstatinModerate

    In patients who receive Daptomycin for Injection, CPK levels should be monitored weekly, and more frequently in patients who received recent prior or concomitant therapy with an HMG-CoA reductase inhibitor or in whom elevations in CPK occur during treatment with Daptomycin for Injection. (Daptomycin label, Warnings and precautions)

  • SimvastatinstatinModerate

    In patients who receive Daptomycin for Injection, CPK levels should be monitored weekly, and more frequently in patients who received recent prior or concomitant therapy with an HMG-CoA reductase inhibitor or in whom elevations in CPK occur during treatment with Daptomycin for Injection. (Daptomycin label, Warnings and precautions)

  • TriamcinolonecorticosteroidModerate

    Eosinophilic pneumonia: Discontinue Daptomycin for Injection and consider treatment with systemic steroids. (Daptomycin label, Warnings and precautions)

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Not medical advice. Severity reflects the label's wording, not your circumstances. A "major" flag can be routine under supervision and a "minor" one can matter at high doses. Ask a pharmacist.