Metyrapone interactions

Metyrapone (Metopirone) has 66 documented interactions across the FDA labels and fact sheets we index: 9 major, 25 moderate, 32 minor, and 0 where a label reports no significant interaction. Each entry below quotes the sentence behind it. This drug page is a starting point, not a verdict for your situation.

Interactions from the label

Major interactions (9)

Moderate interactions (25)

  • Azelastine and fluticasoneantihistamineModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • BeclomethasonecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • BetamethasonecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • BudesonidecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • Budesonide and formoterolcorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • CiclesonidecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • ClobetasolcorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • DeflazacortcorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • DesonidecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • DexamethasonecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • EstradiolestrogenModerate

    Reduced response to metyrapone test. (Estradiol label, Precautions)

  • This may be of clinical significance if a woman becomes pregnant shortly after discontinuing oral contraceptives. h) Increased sulfobromophthalein and other abnormalities in liver function tests may occur. i) Plasma levels of trace minerals may be altered. j) Response to the metyrapone test may be reduced. (Ethynodiol diacetate and ethinyl estradiol label, Precautions)

  • FludrocortisonecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • FlunisolidecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • FluocinonidecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • FluticasonecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • Fluticasone and salmeterolcorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • HalobetasolcorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • HydrocortisonecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • MethylprednisolonecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • MometasonecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • Olopatadine and mometasoneantihistamineModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • PrednisolonecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • PrednisonecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

  • TriamcinolonecorticosteroidModerate

    This can be corrected by giving appropriate doses of corticosteroids. (Metyrapone label, Warnings and precautions)

Minor mentions (32)

  • BrivaracetamanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • Cannabidiol (prescription)anticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • CarbamazepineanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • CenobamateanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • ClobazambenzodiazepineMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • ClonazepambenzodiazepineMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • CyproheptadineantihistamineMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • Divalproex (valproate)anticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • EslicarbazepineanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • EthosuximideanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • FelbamateanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • FosphenytoinanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • GabapentinanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • LacosamideanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • LamotrigineanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • LevetiracetamanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • Methimazoleantithyroid drugMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • MethsuximideanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • OxcarbazepineanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • PerampanelanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • PhenobarbitalbarbiturateMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • Phentermine and topiramateCNS stimulantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • PhenytoinanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • PregabalinanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • PrimidoneanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • Propylthiouracilantithyroid drugMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • RufinamideanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • TiagabineanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • TopiramateanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • Valproic acidanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • VigabatrinanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

  • ZonisamideanticonvulsantMinor

    Anticonvulsants, psychotropic, hormone preparations, corticosteroids, antithyroid agents, cyproheptadine: may affect the results of the metyrapone test. (Metyrapone label, Drug interactions)

Check Metyrapone against everything you take. Add your full list; every pair is checked at once.

Open in the checker

Not medical advice. Severity reflects the label's wording, not your circumstances. A "major" flag can be routine under supervision and a "minor" one can matter at high doses. Ask a pharmacist.