Interaction Checker

Motixafortide interactions

Motixafortide (Aphexda) has 59 documented interactions across the FDA labels and fact sheets we index: 0 major, 59 moderate, 0 minor, and 0 where a label reports no significant interaction. Each entry below quotes the sentence behind it. This drug page is a starting point, not a verdict for your situation.

Interactions from the label

Moderate interactions (59)

  • Acebutololbeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • AcetaminophenModerate

    Premedicate with an analgesic medication (e.g., acetaminophen) prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Acetaminophen and codeineopioidModerate

    Premedicate with an analgesic medication (e.g., acetaminophen) prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Acetaminophen and ibuprofenNSAIDModerate

    Premedicate with an analgesic medication (e.g., acetaminophen) prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Atenololbeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • Atenolol and chlorthalidonebeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • AzelastineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Azelastine and fluticasoneantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Betaxololbeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • Bisoprololbeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • Bisoprolol and hydrochlorothiazidebeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • Brimonidine and timololalpha-adrenergic agonistModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • Brompheniramine, pseudoephedrine, and dextromethorphanantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Butalbital and acetaminophenbarbiturateModerate

    Premedicate with an analgesic medication (e.g., acetaminophen) prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Butalbital, acetaminophen, and caffeinebarbiturateModerate

    Premedicate with an analgesic medication (e.g., acetaminophen) prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Butalbital, acetaminophen, caffeine, and codeinebarbiturateModerate

    Premedicate with an analgesic medication (e.g., acetaminophen) prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • CarbinoxamineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Carvedilolbeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • CetirizineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • ChlorpheniramineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • CimetidineH2 blockerModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • ClemastineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • CyproheptadineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • DesloratadineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • DexchlorpheniramineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • DimenhydrinateantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • DiphenhydramineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Dorzolamide and timololcarbonic anhydrase inhibitorModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • DoxylamineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Doxylamine and pyridoxineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Esmololbeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • FamotidineH2 blockerModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • FexofenadineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • FilgrastimModerate

    Leukocytosis Administration of APHEXDA in conjunction with filgrastim increases circulating leukocytes as well as HSC populations. (Motixafortide label, Warnings and precautions)

  • Hydrocodone and acetaminophenopioidModerate

    Premedicate with an analgesic medication (e.g., acetaminophen) prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Hydrocodone and chlorpheniramineopioidModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • HydroxyzineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Ibuprofen and famotidineNSAIDModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Labetalolbeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • LevocetirizineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • LoratadineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • MeclizineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Metoprololbeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • Metoprolol and hydrochlorothiazidebeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • Nadololbeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • Nebivololbeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • NizatidineH2 blockerModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • OlopatadineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Olopatadine and mometasoneantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Oxycodone and acetaminophenopioidModerate

    Premedicate with an analgesic medication (e.g., acetaminophen) prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Pindololbeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • PromethazineantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Promethazine and codeineopioidModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Promethazine and dextromethorphanantihistamineModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Propranololbeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • RanitidineH2 blockerModerate

    Anaphylactic Shock and Hypersensitivity Reactions: Premedicate all patients with a combination of an H1-antihistamine, an H2 blocker, and a leukotriene inhibitor prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

  • Sotalolbeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • Timololbeta blockerModerate

    Patients receiving concomitant negative chronotropic drugs (e.g., beta blockers) may be more at risk for hypotension in case of hypersensitivity reaction. (Motixafortide label, Warnings and precautions)

  • Tramadol and acetaminophenopioidModerate

    Premedicate with an analgesic medication (e.g., acetaminophen) prior to each APHEXDA dose. (Motixafortide label, Warnings and precautions)

Check Motixafortide against everything you take. Add your full list; every pair is checked at once.

Open in the checker

Not medical advice. Severity reflects the label's wording, not your circumstances. A "major" flag can be routine under supervision and a "minor" one can matter at high doses. Ask a pharmacist.