Butalbital, acetaminophen, caffeine, and codeine and Motixafortide interaction
Butalbital, acetaminophen, caffeine, and codeine and Motixafortide: the Motixafortide prescribing label describes an interaction that usually calls for monitoring, a dose change, or spacing the doses.
Usually manageable with monitoring or a dose change. Tell your pharmacist you take both.
What the FDA labels say
From the Motixafortide (APHEXDA) label · effective 2026-06-04
Premedicate with an analgesic medication (e.g., acetaminophen) prior to each APHEXDA dose.
Injection Site Reactions: The addition of analgesic premedication (e.g., acetaminophen) is recommended.
Taking more than these two? Interactions stack. Check your whole list at once; it stays in your browser.
Open in the checkerNot medical advice. Interaction Checker quotes FDA label text and NIH fact sheets. Whether an interaction matters for you depends on doses, timing, kidney and liver function, and other conditions. Confirm with a pharmacist or prescriber.