Interaction Checker

Interacciones de Acalabrutinib

Acalabrutinib (Calquence) tiene 86 interacciones documentadas en las etiquetas de la FDA y las hojas informativas que indexamos. Graves: 78; moderadas: 8; leves: 0; casos en los que una etiqueta indica que no hay ninguna interacción significativa: 0. Cada entrada de abajo cita la frase que la respalda. Esta página del medicamento es un punto de partida, no un veredicto sobre su situación.

Interacciones según la etiqueta

Interacciones graves (78)

  • AmiodaronaantiarrítmicoGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Aprepitantinhibidor de CYP3A4Grave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Armodafiniloestimulante del SNCGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • AtazanavirantirretroviralGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Bicarbonato de sodioantiácidoGrave

    • Gastric Acid Reducing Agents: Avoid co-administration with proton pump inhibitors (PPIs). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Bosentáninductor de CYP3A4Grave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • CarbamazepinaanticonvulsivoGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • CenobamatoanticonvulsivoGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • CiclosporinainmunosupresorGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Cimetidinaantagonista H2Grave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Claritromicinaantibiótico macrólidoGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • ClobazambenzodiazepinaGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • DarunavirantirretroviralGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Darunavir y cobicistatantirretroviralGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Deferasiroxsuplemento de hierroGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • DexametasonacorticosteroideGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Dexlansoprazolinhibidor de la bomba de protonesGrave

    • Gastric Acid Reducing Agents: Avoid co-administration with proton pump inhibitors (PPIs). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Diltiazembloqueador de los canales de calcioGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • DronedaronaantiarrítmicoGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • EfavirenzantirretroviralGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Efavirenz, lamivudina y tenofovirantirretroviralGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Elvitegravir, cobicistat, emtricitabina y tenofovirantirretroviralGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Eritromicinaantibiótico macrólidoGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • EslicarbazepinaanticonvulsivoGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Esomeprazolinhibidor de la bomba de protonesGrave

    • Gastric Acid Reducing Agents: Avoid co-administration with proton pump inhibitors (PPIs). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • EtravirinaantirretroviralGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • EverolimusinmunosupresorGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Famotidinaantagonista H2Grave

    • Gastric Acid Reducing Agents: Avoid co-administration with proton pump inhibitors (PPIs). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • FenitoínaanticonvulsivoGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • FenobarbitalbarbitúricoGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Fentermina y topiramatoestimulante del SNCGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Fluconazolantifúngico azólicoGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • FosamprenavirantirretroviralGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Fosaprepitantinhibidor de CYP3A4Grave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • FosfenitoínaanticonvulsivoGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • GriseofulvinaantifúngicoGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Ibuprofeno y famotidinaAINEGrave

    • Gastric Acid Reducing Agents: Avoid co-administration with proton pump inhibitors (PPIs). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Imatinibinhibidor de CYP3A4Grave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • IsoniazidaantibióticoGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Itraconazolantifúngico azólicoGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Ivacaftorinhibidor de CYP3A4Grave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Ketoconazolantifúngico azólicoGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Lansoprazolinhibidor de la bomba de protonesGrave

    • Gastric Acid Reducing Agents: Avoid co-administration with proton pump inhibitors (PPIs). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • LenacapavirantirretroviralGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Lopinavir y ritonavirantirretroviralGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Lorlatinibinductor de CYP3A4Grave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Mifepristonainhibidor de CYP3A4Grave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Mirabegrónagonista beta-adrenérgicoGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Mitapivatinductor de CYP3A4Grave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Mitotanoinductor de CYP3A4Grave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Modafiniloestimulante del SNCGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Nafcilinaantibiótico del grupo de las penicilinasGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Naproxeno y esomeprazolAINEGrave

    • Gastric Acid Reducing Agents: Avoid co-administration with proton pump inhibitors (PPIs). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • NefazodonaantidepresivoGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • NevirapinaantirretroviralGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Nirmatrelvir y ritonavirantiviralGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Nizatidinaantagonista H2Grave

    • Gastric Acid Reducing Agents: Avoid co-administration with proton pump inhibitors (PPIs). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Omeprazolinhibidor de la bomba de protonesGrave

    • Gastric Acid Reducing Agents: Avoid co-administration with proton pump inhibitors (PPIs). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Omeprazol y bicarbonato de sodioinhibidor de la bomba de protonesGrave

    • Gastric Acid Reducing Agents: Avoid co-administration with proton pump inhibitors (PPIs). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • OxcarbazepinaanticonvulsivoGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Palbociclibinhibidor de CYP3A4Grave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Pantoprazolinhibidor de la bomba de protonesGrave

    • Gastric Acid Reducing Agents: Avoid co-administration with proton pump inhibitors (PPIs). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • PerampanelanticonvulsivoGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Posaconazolantifúngico azólicoGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • PrimidonaanticonvulsivoGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Rabeprazolinhibidor de la bomba de protonesGrave

    • Gastric Acid Reducing Agents: Avoid co-administration with proton pump inhibitors (PPIs). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Ranitidinaantagonista H2Grave

    • Gastric Acid Reducing Agents: Avoid co-administration with proton pump inhibitors (PPIs). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Ranolazinafármaco que prolonga el intervalo QTGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • RifabutinaantibióticoGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • RifampicinaantibióticoGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • RifapentinaantibióticoGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • RitonavirantirretroviralGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Suvorexantsedante-hipnóticoGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Suzetriginainductor de CYP3A4Grave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Ticagrelorantiagregante plaquetarioGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • TopiramatoanticonvulsivoGrave

    • CYP3A Inducers: Avoid co-administration with strong CYP3A inducers. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Verapamilobloqueador de los canales de calcioGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Voriconazolantifúngico azólicoGrave

    • CYP3A Inhibitors: Avoid co-administration with strong CYP3A inhibitors. (etiqueta de Acalabrutinib, Interacciones medicamentosas)

Interacciones moderadas (8)

  • Acetato de calcioquelante de fosfatoModerada

    • If treatment with a gastric acid reducing agent is required, consider using a H2‑receptor antagonist (e.g., ranitidine or famotidine) or an antacid (e.g., calcium carbonate). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Antiácidos (Tums, Maalox, Mylanta)Productos sin recetaModerada

    Gastric Acid Reducing Agents Clinical Effect • Co-administration of CALQUENCE with a proton pump inhibitor, H2-receptor antagonist, or antacid may decrease acalabrutinib plasma concentrations [see Clinical Pharmacology (12.3) ] . (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • CalcioVitaminas y mineralesModerada

    • If treatment with a gastric acid reducing agent is required, consider using a H2‑receptor antagonist (e.g., ranitidine or famotidine) or an antacid (e.g., calcium carbonate). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Felodipinobloqueador de los canales de calcio dihidropiridínicoModerada

    • If treatment with a gastric acid reducing agent is required, consider using a H2‑receptor antagonist (e.g., ranitidine or famotidine) or an antacid (e.g., calcium carbonate). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Isradipinobloqueador de los canales de calcio dihidropiridínicoModerada

    • If treatment with a gastric acid reducing agent is required, consider using a H2‑receptor antagonist (e.g., ranitidine or famotidine) or an antacid (e.g., calcium carbonate). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Nifedipinobloqueador de los canales de calcio dihidropiridínicoModerada

    • If treatment with a gastric acid reducing agent is required, consider using a H2‑receptor antagonist (e.g., ranitidine or famotidine) or an antacid (e.g., calcium carbonate). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Nimodipinobloqueador de los canales de calcio dihidropiridínicoModerada

    • If treatment with a gastric acid reducing agent is required, consider using a H2‑receptor antagonist (e.g., ranitidine or famotidine) or an antacid (e.g., calcium carbonate). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

  • Nisoldipinobloqueador de los canales de calcio dihidropiridínicoModerada

    • If treatment with a gastric acid reducing agent is required, consider using a H2‑receptor antagonist (e.g., ranitidine or famotidine) or an antacid (e.g., calcium carbonate). (etiqueta de Acalabrutinib, Interacciones medicamentosas)

Compruebe Acalabrutinib frente a todo lo que toma. Añada su lista completa; todos los pares se comprueban a la vez.

Abrir en el verificador

No es un consejo médico. La gravedad refleja la redacción de la etiqueta, no sus circunstancias. Una señal «grave» puede ser algo habitual bajo supervisión y una «leve» puede ser importante a dosis altas. Consulte a un farmacéutico.