Interacciones de Hidroclorotiazida

Hidroclorotiazida (Microzide, HydroDiuril), diurético tiazídico, tiene 354 interacciones documentadas en las etiquetas de la FDA y las hojas informativas que indexamos. Graves: 36; moderadas: 274; leves: 42; casos en los que una etiqueta indica que no hay ninguna interacción significativa: 2. Cada entrada de abajo cita la frase que la respalda. Esta página del medicamento es un punto de partida, no un veredicto sobre su situación.

Interacciones según la etiqueta

Interacciones graves (36)

  • Acetazolamidainhibidor de la anhidrasa carbónicaGrave

    In patients with hypersensitivity to sulfonamide-derived drugs. (etiqueta de Hidroclorotiazida, Contraindicaciones)

  • Ácido etacrínicodiurético de asaGrave

    CONTRAINDICATIONS All diuretics, including ethacrynic acid, are contraindicated in anuria. (etiqueta de Ácido etacrínico, Contraindicaciones)

  • Amiloridadiurético ahorrador de potasioGrave

    Hyperkalemia occurs commonly (about 10%) when amiloride is used without a kaliuretic diuretic. (etiqueta de Amilorida, Advertencia en recuadro)

  • Benazepril e hidroclorotiazidainhibidor de la ECAGrave

    Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (etiqueta de Benazepril e hidroclorotiazida, Contraindicaciones)

  • Bicarbonato de sodioantiácidoGrave

    Sodium bicarbonate injection is contraindicated in patients who are losing chloride by vomiting or from continuous gastrointestinal suction and in patients receiving diuretics known to produce a hypochloremic alkalosis. (etiqueta de Bicarbonato de sodio, Contraindicaciones)

  • Brinzolamidainhibidor de la anhidrasa carbónicaGrave

    In patients with hypersensitivity to sulfonamide-derived drugs. (etiqueta de Hidroclorotiazida, Contraindicaciones)

  • Bumetanidadiurético de asaGrave

    WARNING Bumetanide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. (etiqueta de Bumetanida, Advertencia en recuadro)

  • CiclosporinainmunosupresorGrave

    Potassium-Sparing Diuretics Cyclosporine should not be used with potassium-sparing diuretics because hyperkalemia can occur. (etiqueta de Ciclosporina, Interacciones medicamentosas)

  • Citrato de potasiosuplemento de potasioGrave

    The following drug interactions may occur with potassium citrate: Potassium-sparing diuretics: concomitant administration should be avoided since the simultaneous administration of these agents can produce severe hyperkalemia (7.1) (etiqueta de Citrato de potasio, Interacciones medicamentosas)

  • ClozapinaantipsicóticoGrave

    Use CLOZARIL cautiously in patients with cardiovascular or cerebrovascular disease or conditions predisposing to hypotension (e.g., dehydration, use of antihypertensive medications) [see Dosage and Administration ( 2.2 , 2.6 ), Warnings and Precautions ( 5.2 )]. (etiqueta de Clozapina, Advertencia en recuadro)

  • Because the use of diuretics can accentuate the diminished intravascular volume, avoid diuretics except in the late phase of resolution. (etiqueta de Coriogonadotropina alfa, Advertencias)

  • CONTRAINDICATIONS PROGLYCEM is contraindicated in patients with: Functional hypoglycemia Hypersensitivity to diazoxide, any of the excipients in PROGLYCEM, or other thiazides (etiqueta de Diazóxido, Contraindicaciones)

  • Diclorfenamidainhibidor de la anhidrasa carbónicaGrave

    In patients with hypersensitivity to sulfonamide-derived drugs. (etiqueta de Hidroclorotiazida, Contraindicaciones)

  • DofetilidaantiarrítmicoGrave

    The concomitant use of hydrochlorothiazide (alone or in combinations such as with triamterene) with dofetilide is contraindicated (see PRECAUTIONS, Drug-Drug Interactions ) because this has been shown to significantly increase dofetilide plasma concentrations and QT interval prolongation. (etiqueta de Dofetilida, Contraindicaciones)

  • Dorzolamidainhibidor de la anhidrasa carbónicaGrave

    In patients with hypersensitivity to sulfonamide-derived drugs. (etiqueta de Hidroclorotiazida, Contraindicaciones)

  • Dorzolamida y timololinhibidor de la anhidrasa carbónicaGrave

    In patients with hypersensitivity to sulfonamide-derived drugs. (etiqueta de Hidroclorotiazida, Contraindicaciones)

  • Droperidolantagonista de la dopaminaGrave

    Droperidol should be administered with extreme caution to patients who may be at risk for development of prolonged QT syndrome (e.g., congestive heart failure, bradycardia, use of a diuretic, cardiac hypertrophy, hypokalemia, hypomagnesemia, or administration of other drugs known to increase the QT interval). (etiqueta de Droperidol, Advertencia en recuadro)

  • Enalaprilatoinhibidor de la ECAGrave

    …sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include those with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (etiqueta de Enalaprilato, Advertencias)

  • Eplerenonaantagonista de la aldosteronaGrave

    …• serum creatinine > 2.0 mg/dL in males or >1.8 mg/dL in females, • creatinine clearance < 50 mL/min, or • concomitant administration of potassium supplements or potassium-sparing diuretics (e.g., amiloride, spironolactone, or triamterene) [see Warnings and Precautions (5.1) , Adverse Reactions (6.2) , Drug Interactions (7) , and Clinical Pharmacology (12.3)… (etiqueta de Eplerenona, Contraindicaciones)

  • Eptifibatidaantiagregante plaquetarioGrave

    …of active abnormal bleeding within the previous 30 days Severe hypertension (systolic blood pressure >200 mm Hg or diastolic blood pressure >110 mm Hg) not adequately controlled on antihypertensive therapy Major surgery within the preceding 6 weeks History of stroke within 30 days or any history of hemorrhagic stroke Current or planned administration of another… (etiqueta de Eptifibatida, Contraindicaciones)

  • Because the use of diuretics can accentuate the diminished intravascular volume, diuretics should be avoided except in the late phase of resolution as described below. (etiqueta de Folitropina, Advertencias y precauciones)

  • GentamicinaaminoglucósidoGrave

    The concurrent use of gentamicin with potent diuretics, such as ethacrynic acid or furosemide, should be avoided, since certain diuretics by themselves may cause ototoxicity. (etiqueta de Gentamicina, Advertencia en recuadro)

  • Avoid diuretics or laxatives in patients with diarrhea. (etiqueta de Irinotecán, Advertencias y precauciones)

  • Itraconazolantifúngico azólicoGrave

    Diuretics Eplerenone Contraindicated during and 2 weeks after TOLSURA treatment. (etiqueta de Itraconazol, Interacciones medicamentosas)

  • Metazolamidainhibidor de la anhidrasa carbónicaGrave

    In patients with hypersensitivity to sulfonamide-derived drugs. (etiqueta de Hidroclorotiazida, Contraindicaciones)

  • Metolazonadiurético tiazídicoGrave

    Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

  • MinoxidilvasodilatadorGrave

    Minoxidil should be reserved for hypertensive patients who do not respond adequately to maximum therapeutic doses of a diuretic and two other antihypertensive agents. (etiqueta de Minoxidil, Advertencia en recuadro)

  • NeomicinaaminoglucósidoGrave

    The concurrent use of neomycin with potent diuretics such as ethacrynic acid or furosemide should be avoided, since certain diuretics by themselves may cause ototoxicity. (etiqueta de Neomicina, Advertencia en recuadro)

  • Quinaprilinhibidor de la ECAGrave

    …sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include patients with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (etiqueta de Quinapril, Advertencias)

  • SulfadiazinasulfonamidaGrave

    In patients with hypersensitivity to sulfonamide-derived drugs. (etiqueta de Hidroclorotiazida, Contraindicaciones)

  • Sulfadiazina de platasulfonamidaGrave

    In patients with hypersensitivity to sulfonamide-derived drugs. (etiqueta de Hidroclorotiazida, Contraindicaciones)

  • In patients with hypersensitivity to sulfonamide-derived drugs. (etiqueta de Hidroclorotiazida, Contraindicaciones)

  • SulfasalazinasulfonamidaGrave

    In patients with hypersensitivity to sulfonamide-derived drugs. (etiqueta de Hidroclorotiazida, Contraindicaciones)

  • Tadalafiloinhibidor de la PDE5Grave

    …coadministration of an alpha-blocker and CIALIS for the treatment of BPH has not been adequately studied, and due to the potential vasodilatory effects of combined use resulting in blood pressure lowering, the combination of CIALIS and alpha-blockers is not recommended for the treatment of BPH. [see Dosage and Administration ( 2.7 ), Drug Interactions ( 7.1 ),… (etiqueta de Tadalafilo, Advertencias y precauciones)

  • Trióxido de arsénicofármaco que prolonga el intervalo QTGrave

    The risk of torsade de pointes is related to the extent of QTc prolongation, concomitant administration of QTc prolonging drugs, a history of torsade de pointes, pre-existing QTc interval prolongation, congestive heart failure, administration of potassium-wasting diuretics, or other conditions that result in hypokalemia or hypomagnesemia. (etiqueta de Trióxido de arsénico, Advertencias y precauciones)

  • ZonisamidaanticonvulsivoGrave

    In patients with hypersensitivity to sulfonamide-derived drugs. (etiqueta de Hidroclorotiazida, Contraindicaciones)

Interacciones moderadas (274)

  • AcarbosaantidiabéticoModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • AcebutololbetabloqueanteModerada

    Although β-blockers should be avoided in overt cardiac failure, acebutolol can be used with caution in patients with a history of heart failure who are controlled with digitalis and/or diuretics. (etiqueta de Acebutolol, Advertencias)

  • NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Ácido acetilsalicílico y dipiridamolantiagregante plaquetarioModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Ácido mefenámicoAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Ácido zoledrónicobisfosfonatoModerada

    Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (etiqueta de Ácido zoledrónico, Advertencias y precauciones)

  • AdrenalinasimpaticomiméticoModerada

    …Precautions (5.6) and Adverse Reactions (6) ]. β-blockers, such as propranolol Cyclopropane or halogenated hydrocarbon anesthetics, such as halothane Antihistamines Thyroid hormones Diuretics Cardiac glycosides, such as digitalis glycosides Quinidine Drugs potentiating hypokalemic effects of epinephrine • Potassium depleting diuretics • Corticosteroids • Theophylline… (etiqueta de Adrenalina, Interacciones medicamentosas)

  • AlfuzosinaalfabloqueanteModerada

    Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5.1 ) (etiqueta de Alfuzosina, Advertencias y precauciones)

  • AliskirenoantihipertensivoModerada

    Risk factors for the development of hyperkalemia include renal insufficiency, diabetes, combination use with ARBs or ACEIs [see Contraindications ( 4 ), Warnings and Precautions ( 5.2 ), and Clinical Studies ( 14.3 )] , NSAIDs, or potassium supplements or potassium sparing diuretics. (etiqueta de Aliskireno, Advertencias y precauciones)

  • Alogliptinainhibidor de la DPP-4Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Alogliptina y metforminainhibidor de la DPP-4Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Alopurinolinhibidor de la xantina oxidasaModerada

    Hypersensitivity reactions to allopurinol tablets may be increased in patients with decreased kidney function receiving thiazide diuretics and allopurinol tablets concurrently. (etiqueta de Alopurinol, Advertencias y precauciones)

  • AmikacinaaminoglucósidoModerada

    Ethacrynic Acid, Furosemide, Urea, or Mannitol Some diuretics can enhance aminoglycoside toxicity by altering aminoglycoside concentrations in serum and tissue. (etiqueta de Amikacina, Interacciones medicamentosas)

  • AmiodaronaantiarrítmicoModerada

    Give special attention to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or in patients receiving concomitant diuretics and laxatives. (etiqueta de Amiodarona, Advertencias y precauciones)

  • Amlodipino y benazeprilbloqueador de los canales de calcio dihidropiridínicoModerada

    Symptomatic hypotension is most likely to occur in patients who have heart failure, severe aortic or mitral stenosis, obstructive hypertrophic cardiomyopathy or have been volume or salt depleted as a result of diuretic therapy, dietary salt restriction, dialysis, diarrhea, or vomiting. (etiqueta de Amlodipino y benazepril, Advertencias y precauciones)

  • Amlodipino y olmesartánbloqueador de los canales de calcio dihidropiridínicoModerada

    In patients with an activated renin-angiotensin system, such as volume and/or salt-depleted patients (e.g., those being treated with high doses of diuretics) symptomatic hypotension may be anticipated after initiation of treatment with olmesartan medoxomil . (etiqueta de Amlodipino y olmesartán, Advertencias y precauciones)

  • Amlodipino y valsartánbloqueador de los canales de calcio dihidropiridínicoModerada

    In patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients receiving high doses of diuretics, symptomatic hypotension may occur in patients receiving angiotensin receptor blockers. (etiqueta de Amlodipino y valsartán, Advertencias y precauciones)

  • Amoxicilinaantibiótico del grupo de las penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Hidroclorotiazida, Advertencias y precauciones)

  • Amoxicilina y ácido clavulánicoantibiótico del grupo de las penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Hidroclorotiazida, Advertencias y precauciones)

  • Ampicilinaantibiótico del grupo de las penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Hidroclorotiazida, Advertencias y precauciones)

  • Ampicilina y sulbactamantibiótico del grupo de las penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Hidroclorotiazida, Advertencias y precauciones)

  • Anfepramonaestimulante del SNCModerada

    The pressor effects of diethylpropion and those of other drugs may be additive when the drugs are used concomitantly; conversely, diethylpropion may interfere with antihypertensive drugs (i.e., guanethidine, a-methyldopa). (etiqueta de Anfepramona, Interacciones medicamentosas)

  • Arformoterolagonista beta-adrenérgicoModerada

    Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (etiqueta de Arformoterol, Interacciones medicamentosas)

  • AripiprazolantipsicóticoModerada

    Antihypertensive Drugs Due to its alpha-adrenergic antagonism, aripiprazole has the potential to enhance the effect of certain antihypertensive agents. (etiqueta de Aripiprazol, Interacciones medicamentosas)

  • Armodafiniloestimulante del SNCModerada

    There was also a slightly greater proportion of patients on NUVIGIL requiring new or increased use of antihypertensive medications (2.9%) compared to patients on placebo (1.8%). (etiqueta de Armodafinilo, Advertencias y precauciones)

  • AsenapinaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medications, patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), and patients… (etiqueta de Asenapina, Advertencias y precauciones)

  • AtenololbetabloqueanteModerada

    Because of its relative beta 1 selectivity, however, TENORMIN may be used with caution in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Atenolol, Advertencias)

  • Atenolol y clortalidonabetabloqueanteModerada

    Because of its relative beta 1 -selectivity, however, atenolol and chlorthalidone may be used with caution in patients with bronchospastic disease who do not respond to or cannot tolerate, other antihypertensive treatment. (etiqueta de Atenolol y clortalidona, Advertencias)

  • Atomoxetinainhibidor de la recaptación de noradrenalinaModerada

    Antihypertensive Drugs Prevention or Management Increase the frequency of monitoring blood pressure and adjust atomoxetine oral solution dosage as clinically appropriate. (etiqueta de Atomoxetina, Interacciones medicamentosas)

  • Avanafiloinhibidor de la PDE5Moderada

    • Use of avanafil with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotension ( 2.3 , 5.6 , 5.7 ) (etiqueta de Avanafilo, Advertencias y precauciones)

  • Azilsartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension in Volume- or Salt-Depleted Patients In patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with azilsartan medoxomil. (etiqueta de Azilsartán, Advertencias y precauciones)

  • Belladona y opioopioideModerada

    Diuretics Clinical Impact : Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Belladona y opio, Interacciones medicamentosas)

  • Benazeprilinhibidor de la ECAModerada

    Patients at risk of excessive hypotension include those with the following conditions or characteristics: heart failure with systolic blood pressure below 100 mm Hg, ischemic heart disease, cerebrovascular disease, hyponatremia, high dose diuretic therapy, renal dialysis, or severe volume and/or salt depletion of any etiology. (etiqueta de Benazepril, Advertencias y precauciones)

  • Benzfetaminaestimulante del SNCModerada

    Amphetamines may decrease the hypotensive effect of antihypertensives. (etiqueta de Benzfetamina, Interacciones medicamentosas)

  • Bexagliflozinainhibidor de SGLT2Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • BisoprololbetabloqueanteModerada

    Because of its relative beta 1 -selectivity, however, BISOPROLOL FUMARATE may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (etiqueta de Bisoprolol, Advertencias)

  • Bisoprolol e hidroclorotiazidabetabloqueanteModerada

    Because of the relative beta 1 -selectivity of bisoprolol fumarate, bisoprolol fumarate and hydrochlorothiazide tablets may be used with caution in patients with bronchospastic disease who do not respond to, or who cannot tolerate other antihypertensive treatment. (etiqueta de Bisoprolol e hidroclorotiazida, Advertencias)

  • BortezomibModerada

    Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

  • BrexpiprazolantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medication), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etiqueta de Brexpiprazol, Advertencias y precauciones)

  • Brimonidinaagonista alfa-adrenérgicoModerada

    Antihypertensives/Cardiac Glycosides Because brimonidine tartrate ophthalmic solution 0.1% and 0.15% may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate ophthalmic solution 0.1% and 0.15% is advised. (etiqueta de Brimonidina, Interacciones medicamentosas)

  • Brimonidina y timololagonista alfa-adrenérgicoModerada

    Antihypertensives/Cardiac Glycosides Because brimonidine tartrate/timolol maleate ophthalmic solution may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate/timolol maleate ophthalmic solution is advised. (etiqueta de Brimonidina y timolol, Interacciones medicamentosas)

  • Central Nervous System (CNS) depressants Antihistamines have additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, antianxiety agents, etc.). Antihypertensive drugs Sympathomimetic may reduce the effects of antihypertensive drugs. (etiqueta de Bromfeniramina, pseudoefedrina y dextrometorfano, Interacciones medicamentosas)

  • Bromocriptinaagonista de la dopaminaModerada

    Use caution in patients taking antihypertensive medications. (etiqueta de Bromocriptina, Advertencias y precauciones)

  • Budesonida y formoterolcorticosteroideModerada

    Diuretics: Use with caution. (etiqueta de Budesonida y formoterol, Interacciones medicamentosas)

  • BuprenorfinaopioideModerada

    Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Buprenorfina, Interacciones medicamentosas)

  • Examples: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Buprenorfina y naloxona, Interacciones medicamentosas)

  • NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Butalbital, paracetamol, cafeína y codeína, Interacciones medicamentosas)

  • Calcitriolanálogo de la vitamina DModerada

    Thiazides Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urine. (etiqueta de Calcitriol, Interacciones medicamentosas)

  • Canagliflozinainhibidor de SGLT2Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Candesartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Symptomatic hypotension is most likely to occur in patients who have been volume and/or salt depleted as a result of prolonged diuretic therapy, dietary salt restriction, dialysis, diarrhea, or vomiting. (etiqueta de Candesartán, Advertencias y precauciones)

  • Captoprilinhibidor de la ECAModerada

    Hypotension Excessive hypotension was rarely seen in hypertensive patients but is a possible consequence of captopril use in salt/volume depleted persons (such as those treated vigorously with diuretics), patients with heart failure or those patients undergoing renal dialysis (see PRECAUTIONS : Drug Interactions ). (etiqueta de Captopril, Advertencias)

  • CarbamazepinaanticonvulsivoModerada

    Elderly patients and patients treated with diuretics are at greater risk of developing hyponatremia. (etiqueta de Carbamazepina, Advertencias y precauciones)

  • CarbidopaModerada

    Symptomatic postural hypotension has occurred when carbidopa, given with levodopa or carbidopa-levodopa combination products, was added to the treatment of a patient receiving antihypertensive drugs. (etiqueta de Carbidopa, Interacciones medicamentosas)

  • Carbidopa y levodopafármaco dopaminérgicoModerada

    Antihypertensive drugs: May cause symptomatic postural hypotension. (etiqueta de Carbidopa y levodopa, Interacciones medicamentosas)

  • Carbidopa, levodopa y entacaponafármaco dopaminérgicoModerada

    Antihypertensive Agents Symptomatic postural hypotension has occurred when carbidopa/levodopa was added to the treatment of patients receiving antihypertensive drugs. (etiqueta de Carbidopa, levodopa y entacapona, Interacciones medicamentosas)

  • CariprazinaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etiqueta de Cariprazina, Advertencias y precauciones)

  • CarvedilolbetabloqueanteModerada

    If such symptoms occur, diuretics should be increased and the carvedilol dose should not be advanced until clinical stability resumes [see Dosage and Administration (2) ] . (etiqueta de Carvedilol, Advertencias y precauciones)

  • CefepimacefalosporinaModerada

    Diuretics: Nephrotoxicity has been reported with concomitant administration of cephalosporins with potent diuretics such as furosemide. (etiqueta de Cefepima, Interacciones medicamentosas)

  • CeftazidimacefalosporinaModerada

    Drug Interactions Nephrotoxicity has been reported following concomitant administration of cephalosporins with aminoglycoside antibacterial drugs or potent diuretics such as furosemide. (etiqueta de Ceftazidima, Interacciones medicamentosas)

  • CelecoxibAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Ciclobenzaprinarelajante muscularModerada

    …concomitant use of TONMYA with: MAO inhibitors may be life-threatening [see Contraindications (4) ] , Alcohol, barbiturates, and other CNS depressants may increase the risk of adverse reactions associated with these drugs, Tramadol may increase the seizure risk, Guanethidine or other similar acting drugs may block the antihypertensive action of these drugs. (etiqueta de Ciclobenzaprina, Interacciones medicamentosas)

  • CiclofosfamidainmunosupresorModerada

    …inhibitors: ACE inhibitors can cause leukopenia. ● Natalizumab ● Paclitaxel: Increased hematotoxicity has been reported when cyclophosphamide was administered after paclitaxel infusion. ● Thiazide diuretics ● Zidovudine Increased cardiotoxicity ● Anthracyclines ● Cytarabine ● Pentostatin ● Radiation therapy of the cardiac region ● Trastuzumab Increased pulmonary toxicity… (etiqueta de Ciclofosfamida, Interacciones medicamentosas)

  • Increase the dose of diuretics as needed [see Adverse Reactions (6) ] . (etiqueta de Ciclosilicato de sodio y zirconio, Advertencias y precauciones)

  • CitalopramISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume depleted may be at greater risk for developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (etiqueta de Citalopram, Advertencias y precauciones)

  • ClofarabinaantimetabolitoModerada

    Consider use of diuretics and/or albumin. (etiqueta de Clofarabina, Advertencias y precauciones)

  • Clorotiazidadiurético tiazídicoModerada

    Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Clorotiazida, Advertencias)

  • ClorpromazinaantipsicóticoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Clorpromazina, Precauciones)

  • Clortalidonadiurético tiazídicoModerada

    Effect of chlorthalidone on other drugs Chlorthalidone may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Clortalidona, Interacciones medicamentosas)

  • Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (etiqueta de Cloruro de calcio, Interacciones medicamentosas)

  • CodeínaopioideModerada

    Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Codeína, Interacciones medicamentosas)

  • Colestipolsecuestrador de ácidos biliaresModerada

    Cholestyramine and colestipol: Reduced absorption of thiazides (7.1) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Colestiraminasecuestrador de ácidos biliaresModerada

    Cholestyramine and colestipol: Reduced absorption of thiazides (7.1) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Dapagliflozinainhibidor de SGLT2Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Dapagliflozina y metforminainhibidor de SGLT2Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Desipraminaantidepresivo tricíclicoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with NORPRAMIN. (etiqueta de Desipramina, Advertencias)

  • DesmopresinaModerada

    …Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine). (etiqueta de Desmopresina, Interacciones medicamentosas)

  • DesvenlafaxinaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk [see Use in Specific Populations (8.5) and Clinical Pharmacology (12.3) ] . (etiqueta de Desvenlafaxina, Advertencias y precauciones)

  • Dexlansoprazolinhibidor de la bomba de protonesModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etiqueta de Dexlansoprazol, Advertencias y precauciones)

  • Dexmetilfenidatoestimulante del SNCModerada

    • Antihypertensive Drugs: Monitor blood pressure. (etiqueta de Dexmetilfenidato, Interacciones medicamentosas)

  • DiclofenacoAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Dicloxacilinaantibiótico del grupo de las penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Hidroclorotiazida, Advertencias y precauciones)

  • DiflunisalAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Digoxinaglucósido digitálicoModerada

    Serum potassium levels should be carefully monitored when digoxin is given to patients at high risk of hypokalemia ( e.g. , those receiving diuretics, corticosteroids, or other drugs that commonly lead to potassium loss; those with gastrointestinal losses through diarrhea, vomiting, or nasogastric suction; or those with potassium-losing endocrinopathies or nephropathies). (etiqueta de Digoxina, Advertencias y precauciones)

  • Doxercalciferolanálogo de la vitamina DModerada

    Risk may be increased when used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (etiqueta de Doxercalciferol, Advertencias y precauciones)

  • Drospirenona y etinilestradiolanticonceptivo oralModerada

    Medications that may increase serum potassium concentration include ACE inhibitors, angiotensin-II receptor antagonists, potassium-sparing diuretics, potassium supplementation, heparin, aldosterone antagonists, and NSAIDS. (etiqueta de Drospirenona y etinilestradiol, Advertencias y precauciones)

  • Dulaglutidaagonista del receptor de GLP-1Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • DuloxetinaIRSNModerada

    The risk of BP decreases may be greater in patients taking concomitant medications that induce orthostatic hypotension (such as antihypertensives) or are potent CYP1A2 inhibitors [see Drug Interactions ( 7.1 )] and in patients taking duloxetine delayed-release capsules at doses above 60 mg daily. (etiqueta de Duloxetina, Advertencias y precauciones)

  • Empagliflozinainhibidor de SGLT2Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Empagliflozina y metforminainhibidor de SGLT2Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Enalaprilinhibidor de la ECAModerada

    Patients at risk of excessive hypotension include those with the following conditions or characteristics: heart failure with systolic blood pressure below 100 mmHg, ischemic heart disease, cerebrovascular disease, hyponatremia, high dose diuretic therapy, renal dialysis, or severe volume and/or salt depletion of any etiology. (etiqueta de Enalapril, Advertencias y precauciones)

  • Following initiation and titration of Epogen, approximately 25% of patients on dialysis required initiation of or increases in antihypertensive therapy; hypertensive encephalopathy and seizures have been reported in patients with CKD receiving Epogen. (etiqueta de Epoetina alfa, Advertencias y precauciones)

  • Epoprostenolanálogo de prostaglandinaModerada

    Additional reductions in blood pressure may occur when VELETRI is administered with diuretics, antihypertensive agents, or other vasodilators. (etiqueta de Epoprostenol, Interacciones medicamentosas)

  • EscitalopramISRSModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (etiqueta de Escitalopram, Advertencias y precauciones)

  • EsmololbetabloqueanteModerada

    Antihypertensive agents clonidine, guanfacine, or moxonidine: Beta blockers also increase the risk of clonidine-, guanfacine-, or moxonidine-withdrawal rebound hypertension. (etiqueta de Esmolol, Interacciones medicamentosas)

  • Esomeprazolinhibidor de la bomba de protonesModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etiqueta de Esomeprazol, Advertencias y precauciones)

  • Espironolactonaantagonista de la aldosteronaModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Espironolactona e hidroclorotiazidaantagonista de la aldosteronaModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • EtodolacoAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Exenatidaagonista del receptor de GLP-1Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Fenelzinainhibidor de la MAOModerada

    …hydrochloride desipramine hydrochloride imipramine hydrochloride doxepin carbamazepine cyclobenzaprine HCl amoxapine maprotiline HCl trimipramine maleate protriptyline HCl mirtazapine Phenelzine sulfate should be used with caution in combination with antihypertensive drugs, including thiazide diuretics and β-blockers, since exaggerated hypotensive effects may result. (etiqueta de Fenelzina, Advertencias)

  • FenoprofenoAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • FentaniloopioideModerada

    …treatment with Class 1 and Class III antiarrhythmics, 4) treatment with monoamine oxidase inhibitors (MAOI's), 5) concomitant treatment with other drug products known to prolong the QT interval and 6) electrolyte imbalance, in particular hypokalemia and hypomagnesemia, or concomitant treatment with drugs (e.g., diuretics) that may cause electrolyte imbalance. (etiqueta de Fentanilo, Advertencias y precauciones)

  • Fentermina y topiramatoestimulante del SNCModerada

    Concomitant administration of hydrochlorothiazide alone with topiramate alone has been shown to increase the C max and AUC of topiramate by 27% and 29%, respectively. (etiqueta de Fentermina y topiramato, Interacciones medicamentosas)

  • Fluconazolantifúngico azólicoModerada

    Hydrochlorothiazide In a pharmacokinetic interaction study, coadministration of multiple-dose hydrochlorothiazide to healthy volunteers receiving fluconazole increased plasma concentrations of fluconazole by 40%. (etiqueta de Fluconazol, Interacciones medicamentosas)

  • FludrocortisonacorticosteroideModerada

    Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (etiqueta de Fludrocortisona, Interacciones medicamentosas)

  • FluoxetinaISRSModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (etiqueta de Fluoxetina, Advertencias y precauciones)

  • FlurbiprofenoAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Fluticasona y salmeterolcorticosteroideModerada

    Diuretics: Use with caution. (etiqueta de Fluticasona y salmeterol, Interacciones medicamentosas)

  • FluvoxaminaISRSModerada

    Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (etiqueta de Fluvoxamina, Advertencias y precauciones)

  • Formoterolagonista beta-adrenérgicoModerada

    • Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (etiqueta de Formoterol, Interacciones medicamentosas)

  • FoscarnetantiviralModerada

    When diuretics are indicated, thiazides are recommended over loop diuretics because the latter inhibit renal tubular secretion, and may impair elimination of FOSCAVIR, potentially leading to toxicity. (etiqueta de Foscarnet, Interacciones medicamentosas)

  • Fosinoprilinhibidor de la ECAModerada

    In separate single or multiple dose pharmacokinetic interaction studies with chlorthalidone, nifedipine, propranolol, hydrochlorothiazide, cimetidine, metoclopramide, propantheline, digoxin, and warfarin, the bioavailability of fosinoprilat was not altered by coadministration of fosinopril with any one of these drugs. (etiqueta de Fosinopril, Interacciones medicamentosas)

  • Fosinopril e hidroclorotiazidainhibidor de la ECAModerada

    The thiazide component of fosinopril sodium and hydrochlorothiazide may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic-blocking drugs. (etiqueta de Fosinopril e hidroclorotiazida, Advertencias)

  • Furosemidadiurético de asaModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • GlibenclamidasulfonilureaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Glibenclamida y metforminasulfonilureaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • GlimepiridasulfonilureaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • GlipizidasulfonilureaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Glipizida y metforminasulfonilureaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • HaloperidolantipsicóticoModerada

    Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (etiqueta de Haloperidol, Interacciones medicamentosas)

  • HidrocodonaopioideModerada

    Example: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Hidrocodona, Interacciones medicamentosas)

  • NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Diuretics : Hydrocodone may reduce the efficacy of diuretics. (etiqueta de Hidrocodona y clorfenamina, Interacciones medicamentosas)

  • Diuretics : Hydrocodone may reduce the efficacy of diuretics. (etiqueta de Hidrocodona y homatropina, Interacciones medicamentosas)

  • Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Hidrocodona y paracetamol, Interacciones medicamentosas)

  • HidromorfonaopioideModerada

    Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Hidromorfona, Interacciones medicamentosas)

  • IbuprofenoAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • IloperidonaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etiqueta de Iloperidona, Advertencias y precauciones)

  • Imipraminaantidepresivo tricíclicoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with imipramine hydrochloride tablets. (etiqueta de Imipramina, Advertencias)

  • Indapamidadiurético tiazídicoModerada

    Drug Interactions Other Antihypertensives: Indapamide may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Indapamida, Interacciones medicamentosas)

  • IndometacinaAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Insulina aspartainsulinaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Insulina degludecinsulinaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Insulina detemirinsulinaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Insulina glarginainsulinaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Insulina lisproinsulinaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Ipratropio y salbutamolanticolinérgicoModerada

    Diuretics The electrocardiogram (ECG) changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by β-agonists, especially when the recommended dose of the β-agonist is exceeded. (etiqueta de Ipratropio y salbutamol, Interacciones medicamentosas)

  • Irbesartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension in Volume or Salt-Depleted Patients In patients with an activated renin-angiotensin system, such as volume or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initialization of treatment with AVAPRO. (etiqueta de Irbesartán, Advertencias y precauciones)

  • Ketoconazolantifúngico azólicoModerada

    Diuretics eplerenone The potential increase in plasma concentrations of eplerenone when coadministered with ketoconazole tablets may increase the risk of hyperkalemia and hypotension. (etiqueta de Ketoconazol, Interacciones medicamentosas)

  • KetoprofenoAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • KetorolacoAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Lansoprazolinhibidor de la bomba de protonesModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etiqueta de Lansoprazol, Advertencias y precauciones)

  • LevomilnacipránIRSNModerada

    Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk. (etiqueta de Levomilnaciprán, Advertencias y precauciones)

  • LevorfanolopioideModerada

    Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Levorfanol, Interacciones medicamentosas)

  • Levosalbutamolagonista beta-adrenérgicoModerada

    Diuretics The ECG changes or hypokalemia that may result from the administration of non-potassium-sparing diuretics (such as loop and thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (etiqueta de Levosalbutamol, Interacciones medicamentosas)

  • Linagliptinainhibidor de la DPP-4Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Linagliptina y metforminainhibidor de la DPP-4Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • LinezolidantibióticoModerada

    Monitor serum sodium levels regularly in the elderly, in patients taking diuretics, and in other patients at risk of hyponatremia and/or SIADH while taking Linezolid injection. (etiqueta de Linezolid, Advertencias y precauciones)

  • Liraglutidaagonista del receptor de GLP-1Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Lisinoprilinhibidor de la ECAModerada

    Patients at risk of excessive hypotension include those with the following conditions or characteristics: heart failure with systolic blood pressure below 100 mmHg, ischemic heart disease, cerebrovascular disease, hyponatremia, high dose diuretic therapy, renal dialysis, or severe volume and/or salt depletion of any etiology. (etiqueta de Lisinopril, Advertencias y precauciones)

  • Lisinopril e hidroclorotiazidainhibidor de la ECAModerada

    When a diuretic is added to the therapy of a patient receiving lisinopril, an additional antihypertensive effect is usually observed (see DOSAGE AND ADMINISTRATION ). (etiqueta de Lisinopril e hidroclorotiazida, Interacciones medicamentosas)

  • Litiofármaco serotoninérgicoModerada

    Lithium: Increased lithium concentrations and lithium toxicity (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Losartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension in Volume- or Salt-Depleted Patients In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of treatment with COZAAR. (etiqueta de Losartán, Advertencias y precauciones)

  • LumateperonaantipsicóticoModerada

    Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive drugs), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and patients… (etiqueta de Lumateperona, Advertencias y precauciones)

  • LurasidonaantipsicóticoModerada

    Patients at increased risk of these adverse reactions or at increased risk of developing complications from hypotension include those with dehydration, hypovolemia, treatment with antihypertensive medication, history of cardiovascular disease (e.g., heart failure, myocardial infarction, ischemia, or conduction abnormalities), history of cerebrovascular disease,… (etiqueta de Lurasidona, Advertencias y precauciones)

  • MecamilaminaantihipertensivoModerada

    The action of Mecamylamine HCl may be potentiated by anesthesia, other antihypertensive drugs and alcohol. (etiqueta de Mecamilamina, Interacciones medicamentosas)

  • MeloxicamAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • MetadonaopioideModerada

    Closely monitor patients with risk factors for development of prolonged QT interval (e.g., cardiac hypertrophy, concomitant diuretic use, hypokalemia, hypomagnesemia), a history of cardiac conduction abnormalities, and those taking medications affecting cardiac conduction. (etiqueta de Metadona, Advertencias y precauciones)

  • MetforminabiguanidaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Metilfenidatoestimulante del SNCModerada

    Antihypertensive Drugs: Monitor blood pressure. (etiqueta de Metilfenidato, Interacciones medicamentosas)

  • MetoprololbetabloqueanteModerada

    If such symptoms occur, increase diuretics and restore clinical stability before advancing the dose of Metoprolol Tartrate Tablets [see Dosage and Administration (2) ]. (etiqueta de Metoprolol, Advertencias y precauciones)

  • MiglitolantidiabéticoModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • MilnacipránIRSNModerada

    Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Geriatric Use ( 8.5 )] . (etiqueta de Milnaciprán, Advertencias y precauciones)

  • MirtazapinaantidepresivoModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia [see Use in Specific Populations (8.5) ] . (etiqueta de Mirtazapina, Advertencias y precauciones)

  • Modafiniloestimulante del SNCModerada

    However, a retrospective analysis of the use of antihypertensive medication in these studies showed that a greater proportion of patients on PROVIGIL required new or increased use of antihypertensive medications (2.4%) compared to patients on placebo (0.7%). (etiqueta de Modafinilo, Advertencias y precauciones)

  • Moexiprilinhibidor de la ECAModerada

    Symptomatic hypotension is most likely to occur in patients who have been salt- and volume- depleted as a result of prolonged diuretic therapy, dietary salt restriction, dialysis, diarrhea, or vomiting. (etiqueta de Moexipril, Advertencias)

  • MorfinaopioideModerada

    Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Morfina, Interacciones medicamentosas)

  • NabumetonaAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • NadololbetabloqueanteModerada

    Although beta-blockers should be avoided in overt congestive heart failure, if necessary, they can be used with caution in patients with a history of failure who are well-compensated, usually with digitalis and diuretics. (etiqueta de Nadolol, Advertencias)

  • Nafcilinaantibiótico del grupo de las penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Hidroclorotiazida, Advertencias y precauciones)

  • NalbufinaopioideModerada

    Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Nalbufina, Interacciones medicamentosas)

  • NaproxenoAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • NateglinidameglitinidaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • NiacinaModerada

    Antihypertensive Therapy Niacin may potentiate the effects of ganglionic blocking agents and vasoactive drugs resulting in postural hypotension. (etiqueta de Niacina, Interacciones medicamentosas)

  • Nifedipinobloqueador de los canales de calcio dihidropiridínicoModerada

    Other Diuretics, PDE5 inhibitors, alpha-methyldopa: Nifedipine may increase the blood pressure lowering effect of these concomitantly administered agents. (etiqueta de Nifedipino, Interacciones medicamentosas)

  • Nimodipinobloqueador de los canales de calcio dihidropiridínicoModerada

    Blood Pressure Lowering Drugs Nimodipine may increase the blood pressure lowering effect of concomitantly administered anti-hypertensives such as diuretics, beta-blockers, ACE inhibitors, angiotensin receptor blockers, other calcium channel blockers, α-adrenergic blockers, PDE5 inhibitors, and α-methyldopa. (etiqueta de Nimodipino, Interacciones medicamentosas)

  • NitroglicerinanitratoModerada

    Antihypertensives: Possible additive hypotensive effects. (etiqueta de Nitroglicerina, Interacciones medicamentosas)

  • OlanzapinaantipsicóticoModerada

    …of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, and conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications) where the occurrence of syncope, or hypotension and/or bradycardia might put the patient at increased medical risk. (etiqueta de Olanzapina, Advertencias y precauciones)

  • Olanzapina y fluoxetinaantipsicóticoModerada

    …and fluoxetine capsules should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions that would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (etiqueta de Olanzapina y fluoxetina, Advertencias y precauciones)

  • OliceridinaopioideModerada

    Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Oliceridina, Interacciones medicamentosas)

  • Olmesartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension in Volume- or Salt-Depleted Patients In patients with an activated renin-angiotensin-aldosterone system, such as volume- and/or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may be anticipated after initiation of treatment with Benicar. (etiqueta de Olmesartán, Advertencias y precauciones)

  • Omeprazolinhibidor de la bomba de protonesModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (etiqueta de Omeprazol, Advertencias y precauciones)

  • Omeprazol y bicarbonato de sodioinhibidor de la bomba de protonesModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (etiqueta de Omeprazol y bicarbonato de sodio, Advertencias y precauciones)

  • NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Oxacilinaantibiótico del grupo de las penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Hidroclorotiazida, Advertencias y precauciones)

  • OxaprozinaAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • OxicodonaopioideModerada

    Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Oxicodona, Interacciones medicamentosas)

  • Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Oxicodona y paracetamol, Interacciones medicamentosas)

  • OximorfonaopioideModerada

    Examples: butorphanol, nalbuphine, pentazocine, buprenorphine Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Oximorfona, Interacciones medicamentosas)

  • PaliperidonaantipsicóticoModerada

    Use ERZOFRI with caution in patients with known cardiovascular disease (e.g., heart failure, history of myocardial infarction or ischemia, conduction abnormalities), cerebrovascular disease, or conditions that predispose the patient to hypotension (e.g., dehydration, hypovolemia, and treatment with antihypertensive medications). (etiqueta de Paliperidona, Advertencias y precauciones)

  • Pantoprazolinhibidor de la bomba de protonesModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (etiqueta de Pantoprazol, Advertencias y precauciones)

  • NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Paracetamol y codeínaopioideModerada

    Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Paracetamol y codeína, Interacciones medicamentosas)

  • Paricalcitolanálogo de la vitamina DModerada

    The risk may be increased when Paricalcitol Injection is used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (etiqueta de Paricalcitol, Advertencias y precauciones)

  • ParoxetinaISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SNRIs and SSRIs. [see Use in Specific Populations ( 8.5 )]. (etiqueta de Paroxetina, Advertencias y precauciones)

  • PazopanibModerada

    Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (etiqueta de Pazopanib, Advertencias y precauciones)

  • Penicilina Gantibiótico del grupo de las penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Hidroclorotiazida, Advertencias y precauciones)

  • Penicilina Vantibiótico del grupo de las penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Hidroclorotiazida, Advertencias y precauciones)

  • Pentazocina y naloxonaopioideModerada

    Diuretics Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Pentazocina y naloxona, Interacciones medicamentosas)

  • PentoxifilinametilxantinaModerada

    Small decreases in blood pressure have been observed in some patients treated with pentoxifylline extended-release tablets; periodic systemic blood pressure monitoring is recommended for patients receiving concomitant antihypertensive therapy. (etiqueta de Pentoxifilina, Interacciones medicamentosas)

  • Perindoprilinhibidor de la ECAModerada

    Symptomatic hypotension is most likely to occur in patients who have been volume or salt-depleted as a result of prolonged diuretic therapy, dietary salt restriction, dialysis, diarrhea or vomiting [see Dosage and Administration (2.1) ] . (etiqueta de Perindopril, Advertencias y precauciones)

  • Petidina (meperidina)opioideModerada

    Examples: Cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Petidina (meperidina), Interacciones medicamentosas)

  • PindololbetabloqueanteModerada

    Although beta-blockers should be avoided in overt congestive heart failure, if necessary, pindolol tablets can be used with caution in patients with a history of failure who are well-compensated, usually with digitalis and diuretics. (etiqueta de Pindolol, Advertencias)

  • PioglitazonatiazolidinedionaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Pioglitazona y glimepiridatiazolidinedionaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Pioglitazona y metforminatiazolidinedionaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Piperacilina y tazobactamantibiótico del grupo de las penicilinasModerada

    Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Hidroclorotiazida, Advertencias y precauciones)

  • PiroxicamAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • PrazosinaalfabloqueanteModerada

    Syncopal episodes have usually occurred within 30 to 90 minutes of the initial dose of the drug; occasionally, they have been reported in association with rapid dosage increases or the introduction of another antihypertensive drug into the regimen of a patient taking high doses of prazosin hydrochloride capsules. (etiqueta de Prazosina, Advertencias)

  • ProclorperazinaantipsicóticoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Prometazina y codeínaopioideModerada

    Diuretics : Codeine may reduce the efficacy of diuretics. (etiqueta de Prometazina y codeína, Interacciones medicamentosas)

  • QuetiapinaantipsicóticoModerada

    Quetiapine should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (etiqueta de Quetiapina, Advertencias y precauciones)

  • Quinapril e hidroclorotiazidainhibidor de la ECAModerada

    The thiazide component of quinapril and hydrochlorothiazide tablets may potentiate the action of other antihypertensive drugs, especially ganglionic or peripheral adrenergic- blocking drugs. (etiqueta de Quinapril e hidroclorotiazida, Advertencias)

  • QuinidinaantiarrítmicoModerada

    Drugs that alkalinize the urine ( carbonic-anhydrase inhibitors, sodium bicarbonate, thiazide diuretics ) reduce renal elimination of quinidine. (etiqueta de Quinidina, Interacciones medicamentosas)

  • Rabeprazolinhibidor de la bomba de protonesModerada

    For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (etiqueta de Rabeprazol, Advertencias y precauciones)

  • Ramiprilinhibidor de la ECAModerada

    Experience with another ACE inhibitor suggests that these increases would be reversible upon discontinuation of ramipril and/or diuretic therapy. (etiqueta de Ramipril, Advertencias y precauciones)

  • RepaglinidameglitinidaModerada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • RiociguatvasodilatadorModerada

    Consider the potential for symptomatic hypotension or ischemia in patients with hypovolemia, severe left ventricular outflow obstruction, resting hypotension, autonomic dysfunction, or concomitant treatment with antihypertensives or strong CYP and P-gp/BCRP inhibitors [see Drug Interactions (7.2) and Clinical Pharmacology (12.3) ] . (etiqueta de Riociguat, Advertencias y precauciones)

  • RisperidonaantipsicóticoModerada

    Clinically significant hypotension has been observed with concomitant use of oral RISPERDAL and antihypertensive medication. (etiqueta de Risperidona, Advertencias y precauciones)

  • Sacubitrilo y valsartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients (e.g., those being treated with high doses of diuretics), are at greater risk. (etiqueta de Sacubitrilo y valsartán, Advertencias y precauciones)

  • Salbutamolagonista beta-adrenérgicoModerada

    Diuretics: Use with caution. (etiqueta de Salbutamol, Interacciones medicamentosas)

  • Salmeterolagonista beta-adrenérgicoModerada

    • Diuretics: Use with caution. (etiqueta de Salmeterol, Interacciones medicamentosas)

  • SalsalatoAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Saxagliptinainhibidor de la DPP-4Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Saxagliptina y metforminainhibidor de la DPP-4Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Semaglutidaagonista del receptor de GLP-1Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • SertralinaISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (etiqueta de Sertralina, Advertencias y precauciones)

  • Sildenafiloinhibidor de la PDE5Moderada

    Caution is advised when SILDENAFIL ORAL FILM is co-administered with alpha-blockers or antihypertensives. (etiqueta de Sildenafilo, Advertencias y precauciones)

  • SilodosinaalfabloqueanteModerada

    However, patients in the Phase 3 clinical studies taking concomitant antihypertensive medications with silodosin capsules did not experience a significant increase in the incidence of syncope, dizziness, or orthostasis. (etiqueta de Silodosina, Advertencias y precauciones)

  • Sitagliptinainhibidor de la DPP-4Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Sitagliptina y metforminainhibidor de la DPP-4Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • SorafenibModerada

    Consider temporary or permanent discontinuation for severe or persistent hypertension despite antihypertensive therapy. (etiqueta de Sorafenib, Advertencias y precauciones)

  • SotalolbetabloqueanteModerada

    Special attention should be given to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or patients receiving concomitant diuretic drugs. (etiqueta de Sotalol, Advertencias y precauciones)

  • SulindacoAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Sumatriptán y naproxenotriptánModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • SunitinibModerada

    Initiate and/or adjust antihypertensive therapy as appropriate. (etiqueta de Sunitinib, Advertencias y precauciones)

  • Suxametonio (succinilcolina)bloqueador neuromuscularModerada

    Prolonged Neuromuscular Block in Patients with Hypokalemia or Hypocalcemia Neuromuscular blockade may be prolonged in patients with hypokalemia (e.g., after severe vomiting, diarrhea, digitalisation and diuretic therapy) or hypocalcemia (e.g., after massive transfusions). (etiqueta de Suxametonio (succinilcolina), Advertencias y precauciones)

  • TacrolimusinmunosupresorModerada

    • Hypertension: May require antihypertensive therapy; monitor relevant drug interactions. (etiqueta de Tacrolimus, Advertencias y precauciones)

  • TapentadolopioideModerada

    …use of skeletal muscle relaxants and opioids, consider prescribing naloxone for the emergency treatment of opioid overdose [see Dosage and Administration (2.2) , Warnings and Precautions (5.2 , 5.3) ] Examples: cyclobenzaprine, metaxalone Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Tapentadol, Interacciones medicamentosas)

  • Telmisartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of therapy with telmisartan tablets. (etiqueta de Telmisartán, Advertencias y precauciones)

  • Telmisartán y amlodipinoantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Hypotension Telmisartan In patients with an activated renin-angiotensin system, such as volume- or salt-depleted patients (e.g., those being treated with high doses of diuretics), symptomatic hypotension may occur after initiation of therapy with telmisartan and amlodipine tablets. (etiqueta de Telmisartán y amlodipino, Advertencias y precauciones)

  • TerazosinaalfabloqueanteModerada

    Risk of Hypotension with Concomitant Use of Other Antihypertensive Agents and Phospodiesterase Type 5 Inhibitors (PDE5-I): Concomitant administration of TEZRULY with antihypertensives or phosphodiesterase-5 (PDE-5) inhibitors can result in additive blood pressure lowering effects and symptomatic hypotension (5.3). (etiqueta de Terazosina, Advertencias y precauciones)

  • Terbutalinaagonista beta-adrenérgicoModerada

    Diuretics The ECG changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (etiqueta de Terbutalina, Precauciones)

  • TestosteronaandrógenoModerada

    In patients with hypertension on antihypertensive therapy, TLANDO increased the mean systolic/diastolic BP by 4.8/1.6 mm Hg from baseline. [see Adverse Reactions ( 6.1 )] . (etiqueta de Testosterona, Advertencias y precauciones)

  • Tirzepatidaagonista del receptor de GLP-1Moderada

    Antidiabetic drugs: Dosage adjustment of antidiabetic may be required (7.2) (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • TobramicinaaminoglucósidoModerada

    Some diuretics can enhance aminoglycoside toxicity by altering antibiotic concentrations in serum and tissue. (etiqueta de Tobramicina, Interacciones medicamentosas)

  • TolmetinaAINEModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • TolvaptánModerada

    Co-administration of diuretics also increases the risk of too rapid correction of serum sodium and such patients should undergo close monitoring of serum sodium. (etiqueta de Tolvaptán, Advertencias y precauciones)

  • TopiramatoanticonvulsivoModerada

    Hydrochlorothiazide (HCTZ) Topiramate C max and AUC increased when HCTZ was added to immediate-release topiramate. (etiqueta de Topiramato, Interacciones medicamentosas)

  • Torasemidadiurético de asaModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Toremifenomodulador selectivo de los receptores de estrógenosModerada

    Drugs that decrease renal calcium excretion, e.g., thiazide diuretics, may increase the risk of hypercalcemia in patients receiving FARESTON. (etiqueta de Toremifeno, Interacciones medicamentosas)

  • TramadolopioideModerada

    Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Tramadol, Interacciones medicamentosas)

  • Tramadol y paracetamolopioideModerada

    Diuretics Clinical Impact: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. (etiqueta de Tramadol y paracetamol, Interacciones medicamentosas)

  • Trandolaprilinhibidor de la ECAModerada

    Symptomatic hypotension is most likely to occur in patients who have been salt- or volume-depleted as a result of prolonged treatment with diuretics, dietary salt restriction, dialysis, diarrhea, or vomiting. (etiqueta de Trandolapril, Advertencias)

  • TrazodonaantidepresivoModerada

    Concomitant use with an antihypertensive may require a reduction in the dose of the antihypertensive drug. (etiqueta de Trazodona, Advertencias y precauciones)

  • Triamterenodiurético ahorrador de potasioModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • Triamtereno e hidroclorotiazidadiurético ahorrador de potasioModerada

    NSAID: May lead to increased risk of renal impairment and loss of diuretic and antihypertensive effect (7.1). (etiqueta de Hidroclorotiazida, Interacciones medicamentosas)

  • TrifluoperazinaantipsicóticoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Trifluoperazina, Precauciones)

  • Umeclidinio y vilanterolanticolinérgicoModerada

    • Diuretics: Use with caution. (etiqueta de Umeclidinio y vilanterol, Interacciones medicamentosas)

  • Valsartánantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    In patients with an activated renin-angiotensin system, such as volume- and/or salt-depleted patients receiving high doses of diuretics, symptomatic hypotension may occur. (etiqueta de Valsartán, Advertencias y precauciones)

  • Vardenafiloinhibidor de la PDE5Moderada

    Vardenafil hydrochloride tablets can potentiate the hypotensive effects of nitrates, alpha- blockers, and antihypertensives. (etiqueta de Vardenafilo, Interacciones medicamentosas)

  • VenlafaxinaIRSNModerada

    Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (etiqueta de Venlafaxina, Advertencias y precauciones)

  • Verapamilobloqueador de los canales de calcioModerada

    Control patients with milder ventricular dysfunction, if possible, with optimum doses of digitalis and/or diuretics before verapamil treatment is started [see Drug Interactions ( 7.5 )] . (etiqueta de Verapamilo, Advertencias y precauciones)

  • VilazodonaISRSModerada

    Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs and SNRIs [see Use in Specific Populations ( 8.5 )] . (etiqueta de Vilazodona, Advertencias y precauciones)

  • Vitamina DVitaminas y mineralesModerada

    Los diuréticos tiazídicos reducen la excreción de calcio; combinados con suplementos de vitamina D y de calcio, esto puede llevar a hipercalcemia, sobre todo en adultos mayores. (NIH Office of Dietary Supplements, Vitamin D)

  • VortioxetinaantidepresivoModerada

    Also, patients taking diuretics or who are otherwise volume-depleted can be at greater risk. (etiqueta de Vortioxetina, Advertencias y precauciones)

  • Concurrent use with potassium-containing medications, potassium-sparing diuretics and angiotensin-converting enzyme inhibitors (ACE inhibitors) may result in hyperkalemia and cardiac arrhythmias or cardiac arrest. (etiqueta de Yoduro de potasio, Interacciones medicamentosas)

  • ZiprasidonaantipsicóticoModerada

    Hypokalemia may result from diuretic therapy, diarrhea, and other causes. (etiqueta de Ziprasidona, Advertencias y precauciones)

Menciones leves (42)

  • AmantadinaanticolinérgicoLeve

    Coadministration of 1 Dyazide (triamterene/hydrochlorothiazide) resulted in a higher plasma amantadine hydrochloride concentration in a 61-year old man receiving amantadine hydrochloride 100 mg TID for Parkinson's disease. (etiqueta de Amantadina, Interacciones medicamentosas)

  • Patients required intervention with a diuretic, fluid management, or, in some cases, hospitalization for decompensating heart failure. (etiqueta de Ambrisentán, Advertencias y precauciones)

  • BetaxololbetabloqueanteLeve

    Drug Interactions The following drugs have been coadministered with betaxolol and have not altered its pharmacokinetics: cimetidine, nifedipine, chlorthalidone, and hydrochlorothiazide. (etiqueta de Betaxolol, Interacciones medicamentosas)

  • Bosentáninductor de CYP3A4Leve

    Patients required intervention with a diuretic, fluid management, or hospitalization for decompensating heart failure. (etiqueta de Bosentán, Advertencias y precauciones)

  • ButorfanolopioideLeve

    In such cases, butorphanol should be discontinued and the hypertension treated with antihypertensive drugs. (etiqueta de Butorfanol, Advertencias)

  • CalcioVitaminas y mineralesLeve

    Los diuréticos tiazídicos reducen la excreción de calcio, por lo que una ingesta alta de calcio puede elevar el calcio en sangre. (NIH Office of Dietary Supplements, Calcium)

  • Candesartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Leve

    Most epidemiologic studies examining fetal abnormalities after exposure to antihypertensive use in the first trimester have not distinguished drugs affecting the renin-angiotensin system from other antihypertensive agents. (etiqueta de Candesartán e hidroclorotiazida, Advertencias)

  • Acthar Gel may accentuate the electrolyte loss associated with diuretic therapy. (etiqueta de Corticotropina, Interacciones medicamentosas)

  • Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (etiqueta de Dasatinib, Advertencias y precauciones)

  • Desogestrel y etinilestradiolanticonceptivo oralLeve

    If other contraceptive methods are not suitable, hormonal contraceptive therapy may continue combined with antihypertensive therapy. (etiqueta de Desogestrel y etinilestradiol, Advertencias)

  • Dexanfetaminaestimulante del SNCLeve

    Examples of alkalinizing agents include gastrointestinal alkalinizing agents (e.g., sodium bicarbonate) and urinary alkalinizing agents (e.g. acetazolamide, some thiazides). (etiqueta de Dexanfetamina, Interacciones medicamentosas)

  • Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (etiqueta de Docetaxel, Advertencias y precauciones)

  • DronedaronaantiarrítmicoLeve

    Hypokalemia and Hypomagnesemia with Potassium-Depleting Diuretics Hypokalemia or hypomagnesemia may occur with concomitant administration of potassium-depleting diuretics. (etiqueta de Dronedarona, Advertencias y precauciones)

  • EfedrinasimpaticomiméticoLeve

    Examples: α-adrenergic antagonists, β-adrenergic receptor antagonists, reserpine, quinidine, mephentermine Other Drug Interactions G u anethidine C linical Impact: Ephedrine may inhibit the neuron blockage produced by guanethidine, resulting in loss of antihypertensive effectiveness. (etiqueta de Efedrina, Interacciones medicamentosas)

  • Enalapril e hidroclorotiazidainhibidor de la ECALeve

    Most epidemiologic studies examining fetal abnormalities after exposure to antihypertensive use in the first trimester have not distinguished drugs affecting the renin-angiotensin system from other antihypertensive agents. (etiqueta de Enalapril e hidroclorotiazida, Advertencias)

  • In addition to discontinuation of the drug, diuretic therapy may be required. (etiqueta de Estrógenos esterificados y metiltestosterona, Advertencias)

  • Febuxostatinhibidor de la xantina oxidasaLeve

    In Vivo Drug Interaction Studies Based on drug interaction studies in healthy patients, ULORIC does not have clinically significant interactions with colchicine, naproxen, indomethacin, hydrochlorothiazide, warfarin or desipramine [see Clinical Pharmacology (12.3) ]. (etiqueta de Febuxostat, Interacciones medicamentosas)

  • Finasteridainhibidor de la 5-alfa reductasaLeve

    …clinical studies with acetaminophen, acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, H 2 antagonists and quinolone anti-infectives… (etiqueta de Finasterida, Interacciones medicamentosas)

  • FlecainidaantiarrítmicoLeve

    Flecainide acetate has been used in a large number of patients receiving diuretics without apparent interaction. (etiqueta de Flecainida, Interacciones medicamentosas)

  • Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (etiqueta de Gluconato de calcio, Interacciones medicamentosas)

  • HidralazinavasodilatadorLeve

    When other potent parenteral antihypertensive drugs, such as diazoxide, are used in combination with hydralazine, patients should be continuously observed for several hours for any excessive fall in blood pressure. (etiqueta de Hidralazina, Interacciones medicamentosas)

  • ACE Inhibitors FIRAZYR is a bradykinin B2 receptor antagonist and thereby has the potential to have a pharmacodynamic interaction with ACE inhibitors where FIRAZYR may attenuate the antihypertensive effect of ACE inhibitors. (etiqueta de Icatibant, Interacciones medicamentosas)

  • Imatinibinhibidor de CYP3A4Leve

    Weigh patients regularly and manage unexpected rapid weight gain by drug interruption and diuretics. (etiqueta de Imatinib, Advertencias y precauciones)

  • Isradipinobloqueador de los canales de calcio dihidropiridínicoLeve

    Hydrochlorothiazide: A study in normal healthy volunteers has shown that concomitant administration of isradipine and hydrochlorothiazide does not result in altered pharmacokinetics of either drug. (etiqueta de Isradipino, Interacciones medicamentosas)

  • Postmarketing cases of edema and fluid retention occurring within weeks of starting OPSUMIT, some requiring intervention with a diuretic or hospitalization for decompensated heart failure, have been reported [see Adverse Reactions (6.2) ] . (etiqueta de Macitentán, Advertencias y precauciones)

  • MagnesioVitaminas y mineralesLeve

    El uso a largo plazo de diuréticos de asa y diuréticos tiazídicos aumenta la pérdida de magnesio por la orina. (NIH Office of Dietary Supplements, Magnesium)

  • MetildopaantihipertensivoLeve

    Drug Interactions When methyldopa is used with other antihypertensive drugs, potentiation of antihypertensive effect may occur. (etiqueta de Metildopa, Interacciones medicamentosas)

  • MetilprednisolonacorticosteroideLeve

    Amphotericin B injection and potassium-depleting agents : When corticosteroids are administered concomitantly with potassium-depleting agents (e.g., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etiqueta de Metilprednisolona, Interacciones medicamentosas)

  • MetiltestosteronaandrógenoLeve

    In addition to discontinuation of the drug, diuretic therapy may be required. (etiqueta de Metiltestosterona, Advertencias)

  • Because of its relative beta 1 cardio-selectivity, however, metoprolol tartrate may be used in patients with bronchospastic disease who do not respond to, or cannot tolerate, other antihypertensive treatment. (etiqueta de Metoprolol e hidroclorotiazida, Advertencias y precauciones)

  • MexiletinaantiarrítmicoLeve

    In a large compassionate use program mexiletine has been used concurrently with commonly employed antianginal, antihypertensive, and anticoagulant drugs without observed interactions. (etiqueta de Mexiletina, Interacciones medicamentosas)

  • Milrinonainhibidor de la PDE3Leve

    …been observed in limited experience with patients in whom milrinone was used concurrently with the following drugs: digitalis glycosides; lidocaine, quinidine; hydralazine, prazosin; isosorbide dinitrate, nitroglycerin; chlorthalidone, furosemide, hydrochlorothiazide, spironolactone; captopril; heparin, warfarin, diazepam, insulin; and potassium supplements. (etiqueta de Milrinona, Interacciones medicamentosas)

  • Nisoldipinobloqueador de los canales de calcio dihidropiridínicoLeve

    The blood pressure effect of SULAR tended to be greater in patients on atenolol than in patients on no other antihypertensive therapy. (etiqueta de Nisoldipino, Interacciones medicamentosas)

  • NitroprusiatovasodilatadorLeve

    Hypertensive patients, and patients concomitantly receiving other antihypertensive medications, may be more sensitive to the effects of sodium nitroprusside than normal subjects. (etiqueta de Nitroprusiato, Advertencias)

  • Nortriptilinaantidepresivo tricíclicoLeve

    The antihypertensive action of guanethidine and similar agents may be blocked. (etiqueta de Nortriptilina, Advertencias)

  • PotasioVitaminas y mineralesLeve

    Los diuréticos de asa y los diuréticos tiazídicos aumentan la pérdida de potasio; a veces se prescribe un suplemento junto con ellos. (NIH Office of Dietary Supplements, Potassium)

  • PrednisolonacorticosteroideLeve

    Potassium-depleting agents (e.g., diuretics, Amphotericin B): When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etiqueta de Prednisolona, Interacciones medicamentosas)

  • PrednisonacorticosteroideLeve

    Potassium-Depleting Agents (e.g., Diuretics, Amphotericin B) When corticosteroids are administered concomitantly with potassium-depleting agents, patients should be observed closely for development of hypokalemia. (etiqueta de Prednisona, Interacciones medicamentosas)

  • Protriptilinaantidepresivo tricíclicoLeve

    Protriptyline may block the antihypertensive effect of guanethidine or similarly acting compounds. (etiqueta de Protriptilina, Advertencias)

  • TerbinafinaantifúngicoLeve

    There is no information available from adequate drug-drug interaction studies with the following classes of drugs: oral contraceptives, hormone replacement therapies, hypoglycemics, phenytoins, thiazide diuretics, and calcium channel blockers. (etiqueta de Terbinafina, Interacciones medicamentosas)

  • TriamcinolonacorticosteroideLeve

    Amphotericin B injection and potassium-depleting agents: When corticosteroids are administered concomitantly with potassium-depleting agents ( i.e., amphotericin B, diuretics), patients should be observed closely for development of hypokalemia. (etiqueta de Triamcinolona, Interacciones medicamentosas)

  • ZincVitaminas y mineralesLeve

    Los diuréticos tiazídicos aumentan la pérdida de zinc por la orina con el uso a largo plazo. (NIH Office of Dietary Supplements, Zinc)

Sin interacción significativa según la etiqueta (2)

  • PamidronatobisfosfonatoSin interacción

    Loop Diuretics Concomitant administration of a loop diuretic had no effect on the calcium-lowering action of pamidronate disodium. (etiqueta de Pamidronato, Interacciones medicamentosas)

  • Ropinirolagonista de la dopaminaSin interacción

    Commonly Administered Drugs: Population analysis showed that commonly administered drugs (e.g., selegiline, amantadine, tricyclic antidepressants, benzodiazepines, ibuprofen, thiazides, antihistamines, anticholinergics) did not affect the clearance of ropinirole. (etiqueta de Ropinirol, Interacciones medicamentosas)

Compruebe Hidroclorotiazida frente a todo lo que toma. Añada su lista completa; todos los pares se comprueban a la vez.

Abrir en el verificador

No es un consejo médico. La gravedad refleja la redacción de la etiqueta, no sus circunstancias. Una señal «grave» puede ser algo habitual bajo supervisión y una «leve» puede ser importante a dosis altas. Consulte a un farmacéutico.