Interacciones de Levotiroxina
Levotiroxina (Synthroid, Levoxyl, Unithroid), hormona tiroidea, tiene 280 interacciones documentadas en las etiquetas de la FDA y las hojas informativas que indexamos. Graves: 17; moderadas: 222; leves: 40; casos en los que una etiqueta indica que no hay ninguna interacción significativa: 1. Cada entrada de abajo cita la frase que la respalda. Esta página del medicamento es un punto de partida, no un veredicto sobre su situación.
Sobre Levotiroxina
Datos, mitos y afirmaciones en internetLa levotiroxina es una forma sintética de la tiroxina (T4), la principal hormona producida por la glándula tiroides. Se prescribe para el hipotiroidismo, una afección en la que la tiroides no produce suficiente hormona, y junto con la cirugía o el yodo radiactivo para algunos cánceres de tiroides. Suele tomarse en un comprimido al día con el estómago vacío, de 30 a 60 minutos antes del desayuno, con agua. La dosis se ajusta mediante análisis de sangre, principalmente de TSH, y el tratamiento suele ser a largo plazo.
Interacciones según la etiqueta
Interacciones graves (17)
Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-adrenergic blocking agents that might precipitate a thyroid storm. (etiqueta de Brimonidina y timolol, Advertencias y precauciones)
Clomiphene citrate tablets are contraindicated in patients with uncontrolled thyroid or adrenal dysfunction or in the presence of an organic intracranial lesion such as pituitary tumor (see INDICATIONS AND USAGE). (etiqueta de Clomifeno, Contraindicaciones)
Presence of uncontrolled non-gonadal endocrinopathies (e.g., thyroid, adrenal, or pituitary disorders). (etiqueta de Coriogonadotropina alfa, Contraindicaciones)
When concomitant administration of corticosteroids and levothyroxine is required, administration of corticosteroid should precede the initiation of levothyroxine therapy to avoid adrenal crisis. (etiqueta de Dexametasona, Advertencias y precauciones)
Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-adrenergic blocking agents that might precipitate a thyroid storm. (etiqueta de Dorzolamida y timolol, Advertencias y precauciones)
WARNING: RISK OF THYROID C-CELL TUMORS In male and female rats, dulaglutide causes a dose-related and treatment-duration-dependent increase in the incidence of thyroid C-cell tumors (adenomas and carcinomas) after lifetime exposure. (etiqueta de Dulaglutida, Advertencia en recuadro)
- FolitropinaGrave
Reactions including anaphylaxis have been reported [see Adverse Reactions (6.2) ] High levels of FSH indicating primary gonadal failure Presence of uncontrolled non-gonadal endocrinopathies (e.g., thyroid, adrenal, or pituitary disorders) [see Indications and Usage (1.1 , 1.2 , 1.3) ] Hypersensitivity reactions to streptomycin or neomycin. (etiqueta de Folitropina, Contraindicaciones)
Do not take thyroid hormone replacement therapy within 2 hours of dosing with LANTHANUM CARBONATE. (etiqueta de Lantano, Interacciones medicamentosas)
WARNING: RISK OF THYROID C-CELL TUMORS • Liraglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures in both genders of rats and mice. (etiqueta de Liraglutida, Advertencia en recuadro)
Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-adrenergic blockade which might precipitate a thyroid storm. (etiqueta de Nadolol, Advertencias)
Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-blockade which might precipitate a thyroid crisis. (etiqueta de Pindolol, Advertencias)
Avoid abrupt withdrawal of beta-blockade, which may precipitate a thyroid storm. (etiqueta de Propranolol, Advertencias y precauciones)
WARNING: RISK OF THYROID C-CELL TUMORS • In rodents, semaglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. (etiqueta de Semaglutida, Advertencia en recuadro)
Thyroid Abnormalities Avoid abrupt withdrawal of beta-blockade which might be followed by an exacerbation of symptoms of hyperthyroidism, including thyroid storm. (etiqueta de Sotalol, Advertencias y precauciones)
Patients suspected of developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal of beta-adrenergic blocking agents that might precipitate a thyroid storm. (etiqueta de Timolol, Advertencias y precauciones)
WARNING: RISK OF THYROID C-CELL TUMORS In rats, tirzepatide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. (etiqueta de Tirzepatida, Advertencia en recuadro)
People who have thyroid problems (hyperthyroidism) may have a higher chance of having a hypertensive crisis. (etiqueta de Tranilcipromina, Advertencia en recuadro)
Interacciones moderadas (222)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Drug or Drug Class Effect Beta-adrenergic antagonists e.g., Propranolol > 160 mg/day) In patients treated with large doses of propranolol (> 160 mg/day), T 3 and T 4 levels change slightly, TSH levels remain normal, and patients are clinically euthyroid. (etiqueta de Levotiroxina, Interacciones medicamentosas)
An initial increase in serum FT 4 is followed by return of FT 4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T 4 levels may decrease by as much as 30%. (etiqueta de Levotiroxina, Interacciones medicamentosas)
An initial increase in serum FT 4 is followed by return of FT 4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T 4 levels may decrease by as much as 30%. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Levothyroxine The bioavailability of alendronate was slightly decreased when BINOSTO and levothyroxine were co-administered to healthy subjects [see Clinical Pharmacology (12.3) ] . (etiqueta de Alendronato, Interacciones medicamentosas)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Other drugs: Amiodarone Amiodarone inhibits peripheral conversion of levothyroxine (T4) to triiodothyronine (T3) and may cause isolated biochemical changes (increase in serum free-T4, and decreased or normal free-T3) in clinically euthyroid patients. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Oral Anticoagulants Levothyroxine increases the response to oral anticoagulant therapy. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Oral Anticoagulants Levothyroxine increases the response to oral anticoagulant therapy. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Drug or Drug Class Effect Beta-adrenergic antagonists e.g., Propranolol > 160 mg/day) In patients treated with large doses of propranolol (> 160 mg/day), T 3 and T 4 levels change slightly, TSH levels remain normal, and patients are clinically euthyroid. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Drug or Drug Class Effect Beta-adrenergic antagonists e.g., Propranolol > 160 mg/day) In patients treated with large doses of propranolol (> 160 mg/day), T 3 and T 4 levels change slightly, TSH levels remain normal, and patients are clinically euthyroid. (etiqueta de Levotiroxina, Interacciones medicamentosas)
- AxitinibModerada
Monitor thyroid function before initiation of, and periodically throughout, treatment with INLYTA. (etiqueta de Axitinib, Advertencias y precauciones)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
An initial increase in serum FT 4 is followed by return of FT 4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T 4 levels may decrease by as much as 30%. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Drug or Drug Class Effect Beta-adrenergic antagonists e.g., Propranolol > 160 mg/day) In patients treated with large doses of propranolol (> 160 mg/day), T 3 and T 4 levels change slightly, TSH levels remain normal, and patients are clinically euthyroid. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Monitor and replace thyroid hormone if needed. (etiqueta de Bexaroteno, Advertencias y precauciones)
Androgens/Anabolic Steroids Asparaginase Glucocorticoids Slow-Release Nictonic Acid These drugs may decrease serum TBG concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Drug or Drug Class Effect Beta-adrenergic antagonists e.g., Propranolol > 160 mg/day) In patients treated with large doses of propranolol (> 160 mg/day), T 3 and T 4 levels change slightly, TSH levels remain normal, and patients are clinically euthyroid. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Drug or Drug Class Effect Beta-adrenergic antagonists e.g., Propranolol > 160 mg/day) In patients treated with large doses of propranolol (> 160 mg/day), T 3 and T 4 levels change slightly, TSH levels remain normal, and patients are clinically euthyroid. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Oral Anticoagulants Levothyroxine increases the response to oral anticoagulant therapy. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
An initial increase in serum FT 4 is followed by return of FT 4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T 4 levels may decrease by as much as 30%. (etiqueta de Levotiroxina, Interacciones medicamentosas)
An initial increase in serum FT 4 is followed by return of FT 4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T 4 levels may decrease by as much as 30%. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Los suplementos de calcio pueden reducir la absorción de estos medicamentos; tómelos con varias horas de separación. (NIH Office of Dietary Supplements, Calcium)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Phenytoin and carbamazepine reduce serum protein binding of levothyroxine, and total and free T4 may be reduced by 20% to 40%, but most patients have normal serum TSH levels and are clinically euthyroid. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Drug or Drug Class Effect Beta-adrenergic antagonists e.g., Propranolol > 160 mg/day) In patients treated with large doses of propranolol (> 160 mg/day), T 3 and T 4 levels change slightly, TSH levels remain normal, and patients are clinically euthyroid. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Concomitant use with colesevelam hydrochloride may decrease the exposure of the following drugs: Drugs with a narrow therapeutic index (e.g., cyclosporine), phenytoin, thyroid hormone replacement therapy, warfarin, oral contraceptives containing ethinyl estradiol and norethindrone, olmesartan medoxomil, and sulfonylureas (glimepiride, glipizide, glyburide). (etiqueta de Colesevelam, Interacciones medicamentosas)
Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (etiqueta de Colestiramina, Interacciones medicamentosas)
Oral Anticoagulants Levothyroxine increases the response to oral anticoagulant therapy. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Androgens/Anabolic Steroids Asparaginase Glucocorticoids Slow-Release Nictonic Acid These drugs may decrease serum TBG concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
An initial increase in serum FT 4 is followed by return of FT 4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T 4 levels may decrease by as much as 30%. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Digitalis Glycosides Levothyroxine may reduce the therapeutic effects of digitalis glycosides. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Oral Anticoagulants Levothyroxine increases the response to oral anticoagulant therapy. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Oral Anticoagulants Levothyroxine increases the response to oral anticoagulant therapy. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Abnormal Thyroid Function Tests Dose-dependent decreases in serum T3 and T4 (free and total) values have been observed in patients taking APTIOM. (etiqueta de Eslicarbazepina, Advertencias y precauciones)
Drug or Drug Class Effect Beta-adrenergic antagonists e.g., Propranolol > 160 mg/day) In patients treated with large doses of propranolol (> 160 mg/day), T 3 and T 4 levels change slightly, TSH levels remain normal, and patients are clinically euthyroid. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Phenytoin and carbamazepine reduce serum protein binding of levothyroxine, and total and free T4 may be reduced by 20% to 40%, but most patients have normal serum TSH levels and are clinically euthyroid. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Drug or Drug Class Effect Phenobarbital Rifampin Phenobarbital has been shown to reduce the response to thyroxine. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Drug or Drug Class Effect Phenobarbital Rifampin Phenobarbital has been shown to reduce the response to thyroxine. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
…Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Androgens/Anabolic Steroids Asparaginase Glucocorticoids Slow-Release Nictonic Acid These drugs may decrease serum TBG concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Oral Anticoagulants Levothyroxine increases the response to oral anticoagulant therapy. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Furosemide has been shown to inhibit the protein binding of T4 to TBG and albumin, causing an increase free T4 fraction in serum. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Oral Anticoagulants Levothyroxine increases the response to oral anticoagulant therapy. (etiqueta de Levotiroxina, Interacciones medicamentosas)
- HialuronidasaModerada
…recommended that appropriate references first be consulted to determine the usual precautions for the use of the other drug; e.g., when epinephrine is injected along with hyaluronidase, the precautions for the use of epinephrine in cardiovascular disease, thyroid disease, diabetes, digital nerve block, ischemia of the fingers and toes etc., should be observed. (etiqueta de Hialuronidasa, Interacciones medicamentosas)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
El hierro reduce la absorción de estos medicamentos; tómelos con unas horas de separación. (NIH Office of Dietary Supplements, Iron)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
- Interferón beta-1aModerada
Thyroid function should be monitored periodically. (etiqueta de Interferón beta-1a, Advertencias y precauciones)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Drug or Drug Class Effect Beta-adrenergic antagonists e.g., Propranolol > 160 mg/day) In patients treated with large doses of propranolol (> 160 mg/day), T 3 and T 4 levels change slightly, TSH levels remain normal, and patients are clinically euthyroid. (etiqueta de Levotiroxina, Interacciones medicamentosas)
- LanreotidaModerada
Thyroid Function Abnormalities : Decreases in thyroid function may occur; perform tests where clinically indicated. (etiqueta de Lanreotida, Advertencias y precauciones)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Other drugs: Amiodarone Amiodarone inhibits peripheral conversion of levothyroxine (T4) to triiodothyronine (T3) and may cause isolated biochemical changes (increase in serum free-T4, and decreased or normal free-T3) in clinically euthyroid patients. (etiqueta de Liotironina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
• Hypothyroidism and Hyperthyroidism: Monitor thyroid function regularly ( 5.7 ). (etiqueta de Litio, Advertencias y precauciones)
…Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
An initial increase in serum FT 4 is followed by return of FT 4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T 4 levels may decrease by as much as 30%. (etiqueta de Levotiroxina, Interacciones medicamentosas)
An initial increase in serum FT 4 is followed by return of FT 4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T 4 levels may decrease by as much as 30%. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Androgens/Anabolic Steroids Asparaginase Glucocorticoids Slow-Release Nictonic Acid These drugs may decrease serum TBG concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Drug or Drug Class Effect Beta-adrenergic antagonists e.g., Propranolol > 160 mg/day) In patients treated with large doses of propranolol (> 160 mg/day), T 3 and T 4 levels change slightly, TSH levels remain normal, and patients are clinically euthyroid. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Drug or Drug Class Effect Beta-adrenergic antagonists e.g., Propranolol > 160 mg/day) In patients treated with large doses of propranolol (> 160 mg/day), T 3 and T 4 levels change slightly, TSH levels remain normal, and patients are clinically euthyroid. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Drug or Drug Class Effect Beta-adrenergic antagonists e.g., Propranolol > 160 mg/day) In patients treated with large doses of propranolol (> 160 mg/day), T 3 and T 4 levels change slightly, TSH levels remain normal, and patients are clinically euthyroid. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…1: Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
- OctreotidaModerada
Thyroid Function Abnormalities MYCAPSSA suppresses the secretion of thyroid-stimulating hormone, which may result in hypothyroidism. (etiqueta de Octreotida, Advertencias y precauciones)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
An initial increase in serum FT 4 is followed by return of FT 4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T 4 levels may decrease by as much as 30%. (etiqueta de Levotiroxina, Interacciones medicamentosas)
- OrlistatModerada
Drug Interactions and Decreased Vitamin Absorption ORLISTAT may interact with concomitant drugs including cyclosporine, levothyroxine, warfarin, amiodarone, antiepileptic drugs, and antiretroviral drugs [see Drug Interactions (7) ]. (etiqueta de Orlistat, Advertencias y precauciones)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
- PasireotidaModerada
Monitoring pituitary function (e.g., thyroid, adrenal, gonadal) prior to initiation of therapy with SIGNIFOR LAR, as well as periodically during treatment, as clinically appropriate, is recommended. (etiqueta de Pasireotida, Advertencias y precauciones)
- PazopanibModerada
Hypothyroidism : Monitor thyroid tests at baseline, during treatment and as clinically indicated and manage hypothyroidism as appropriate. (etiqueta de Pazopanib, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Hypothyroidism Adults: Clinical trials with quetiapine demonstrated dose-related decreases in thyroid hormone levels. (etiqueta de Quetiapina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Drug or Drug Class Effect Phenobarbital Rifampin Phenobarbital has been shown to reduce the response to thyroxine. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…levonorgestrel Immunosuppressants Cyclosporine, tacrolimus Methylxanthines Theophylline Narcotic analgesics Methadone Phosphodiesterase-5 (PDE-5) Inhibitors Sildenafil Thyroid preparations Levothyroxine Tricyclic antidepressants Amitriptyline, nortriptyline 7.5 Other Interactions The conversion of PRIFTIN to 25-desacetyl rifapentine is mediated by an esterase enzyme. (etiqueta de Rifapentina, Interacciones medicamentosas)
Oral Anticoagulants Levothyroxine increases the response to oral anticoagulant therapy. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
An initial increase in serum FT 4 is followed by return of FT 4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T 4 levels may decrease by as much as 30%. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Administration of sertraline in patients stabilized on levothyroxine may result in increased levothyroxine requirements. (etiqueta de Levotiroxina, Interacciones medicamentosas)
For oral medication where a reduction in the bioavailability of that medication would have a clinically significant effect on its safety or efficacy (e.g., cyclosporine, tacrolimus, levothyroxine), consider separation of the timing of the administration of the two drugs [see Clinical Pharmacology (12.3) ] . (etiqueta de Sevelámero, Interacciones medicamentosas)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Worsening of Diabetic Control : May worsen glycemic control and result in increased antidiabetic agent or insulin requirements. (etiqueta de Levotiroxina, Advertencias y precauciones)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
- SomatropinaModerada
Hypothyroidism: Monitor thyroid function periodically as hypothyroidism may occur or worsen after initiation of somatropin. (etiqueta de Somatropina, Advertencias y precauciones)
- SorafenibModerada
• Impairment of Thyroid Stimulating Hormone Suppression (TSH) in DTC : Monitor TSH monthly and adjust thyroid replacement therapy in patients with thyroid cancer. (etiqueta de Sorafenib, Advertencias y precauciones)
An initial increase in serum FT 4 is followed by return of FT 4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T 4 levels may decrease by as much as 30%. (etiqueta de Levotiroxina, Interacciones medicamentosas)
An initial increase in serum FT 4 is followed by return of FT 4 to normal levels with sustained therapeutic serum salicylate concentrations, although total T 4 levels may decrease by as much as 30%. (etiqueta de Levotiroxina, Interacciones medicamentosas)
- SunitinibModerada
• Thyroid Dysfunction : Monitor thyroid function at baseline, periodically during treatment, and as clinically indicated. (etiqueta de Sunitinib, Advertencias y precauciones)
…Drugs That May Alter T 4 and Triiodothyronine (T 3 ) Serum Transport Without Effecting Free Thyroxine (FT 4 ) Concentration (Euthyroidism) Drug or Drug Class Effect Clofibrate Estrogen-containing oral contraceptives Estrogens (oral) Heroin/Methadone 5-Fluorouracil Mitotane Tamoxifen These drugs may increase serum thyroxine-binding globulin (TBG) concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Androgens/Anabolic Steroids Asparaginase Glucocorticoids Slow-Release Nictonic Acid These drugs may decrease serum TBG concentration. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Failure to do so may precipitate an acute adrenal crisis when thyroid hormone therapy is initiated, due to increased metabolic clearance of glucocorticoids by thyroid hormone. (etiqueta de Levotiroxina, Advertencias y precauciones)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Sympathomimetics Concurrent use may of sympathomimetics and levothyroxine may increase the effects of sympathomimetics or thyroid hormone. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Antidepressant Therapy Concurrent use of tricyclic (e.g., amitriptyline) or tetracyclic (e.g., maprotiline) antidepressants and levothyroxine may increase the therapeutic and toxic effects of both drugs, possibly due to increased receptor sensitivity to catecholamines. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Oral Anticoagulants Levothyroxine increases the response to oral anticoagulant therapy. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Menciones leves (40)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Effect on Ketone and Thyroid Function Tests Valproate is partially eliminated in the urine as a keto-metabolite which may lead to a false interpretation of the urine ketone test. (etiqueta de Ácido valproico, Advertencias y precauciones)
Hypocalcemia and Mineral Metabolism Preexisting hypocalcemia and disturbances of mineral metabolism (e.g., hypoparathyroidism, thyroid surgery, parathyroid surgery; malabsorption syndromes, excision of small intestine) must be effectively treated before initiating therapy with Reclast. (etiqueta de Ácido zoledrónico, Advertencias y precauciones)
- BusulfanoLeve
Cytologic abnormalities characterized by giant, hyperchromatic nuclei have been reported in lymph nodes, pancreas, thyroid, adrenal glands, liver, and bone marrow. (etiqueta de Busulfano, Advertencias)
Changes in thyroid status may occur if barbiturates are added or withdrawn from patients being treated for hypothyroidism. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Secondary malignancies (urinary tract cancer, myelodysplasia, acute leukemias, lymphomas, thyroid cancer, and sarcomas) have been reported in patients treated with cyclophosphamide-containing regimens . (etiqueta de Ciclofosfamida, Advertencias y precauciones)
Losartan, glipizide and levothyroxine did not show any changes in exposure when co-administered with LOKELMA. (etiqueta de Ciclosilicato de sodio y zirconio, Interacciones medicamentosas)
- CisteaminaLeve
Other Medications Used for the Management of Fanconi Syndrome PROCYSBI can be administered with other electrolyte and mineral replacements necessary for management of Fanconi syndrome, as well as vitamin D and thyroid hormone. (etiqueta de Cisteamina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Effect on Ketone and Thyroid Function Tests Valproate is partially eliminated in the urine as a keto-metabolite which may lead to a false interpretation of the urine ketone test. (etiqueta de Divalproato de sodio (valproato), Advertencias y precauciones)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
- IfosfamidaLeve
Cases of myelodysplastic syndrome, acute leukemias, lymphomas, thyroid cancers, and sarcomas have occurred and may develop several years after chemotherapy has been discontinued. (etiqueta de Ifosfamida, Advertencias y precauciones)
Hypothyroidism has been reported in thyroidectomy patients undergoing levothyroxine replacement. (etiqueta de Imatinib, Advertencias y precauciones)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Ketamine Concurrent use of ketamine and levothyroxine may produce marked hypertension and tachycardia. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
- LenalidomidaLeve
Thyroid Disorders Both hypothyroidism and hyperthyroidism have been reported [see Adverse Reactions (6.2) ] . (etiqueta de Lenalidomida, Advertencias y precauciones)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Changes in thyroid status may occur if barbiturates are added or withdrawn from patients being treated for hypothyroidism. (etiqueta de Levotiroxina, Interacciones medicamentosas)
EMROSI may induce hyperpigmentation in many organs, including nails, bone, skin, eyes, thyroid, visceral tissue, oral cavity (teeth, mucosa, alveolar bone), sclerae and heart valves. (etiqueta de Minociclina, Advertencias y precauciones)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
…performed, the following concomitant drugs were used in at least 10% of patients in either or both Sjogren's efficacy studies: acetylsalicylic acid, artificial tears, calcium, conjugated estrogens, hydroxychloroquine sulfate, ibuprofen, levothyroxine sodium, medroxyprogesterone acetate, methotrexate, multivitamins, naproxen, omeprazole, paracetamol, and prednisone. (etiqueta de Pilocarpina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Changes in thyroid status may occur if barbiturates are added or withdrawn from patients being treated for hypothyroidism. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Other drugs: Carbamazepine Furosemide (> 80 mg IV) Heparin Hydantoins Non-Steroidal Anti-Inflammatory Drugs - Fenamates These drugs may cause protein-binding site displacement. (etiqueta de Levotiroxina, Interacciones medicamentosas)
Warnings Potassium iodide can cause fetal harm, abnormal thyroid function, and goiter when administered to a pregnant woman. (etiqueta de Yoduro de potasio, Advertencias)
Sin interacción significativa según la etiqueta (1)
…adjustment is needed when SINGULAIR is co-administered with theophylline, prednisone, prednisolone, oral contraceptives, fexofenadine, digoxin, warfarin, gemfibrozil, itraconazole, thyroid hormones, sedative hypnotics, non-steroidal anti-inflammatory agents, benzodiazepines, decongestants, and Cytochrome P450 (CYP) enzyme inducers [see Clinical Pharmacology (12.3)… (etiqueta de Montelukast, Interacciones medicamentosas)
Compruebe Levotiroxina frente a todo lo que toma. Añada su lista completa; todos los pares se comprueban a la vez.
Abrir en el verificadorNo es un consejo médico. La gravedad refleja la redacción de la etiqueta, no sus circunstancias. Una señal «grave» puede ser algo habitual bajo supervisión y una «leve» puede ser importante a dosis altas. Consulte a un farmacéutico.