Interacciones de Proclorperazina

Proclorperazina (Compazine, Compro), antipsicótico, tiene 376 interacciones documentadas en las etiquetas de la FDA y las hojas informativas que indexamos. Graves: 131; moderadas: 164; leves: 79; casos en los que una etiqueta indica que no hay ninguna interacción significativa: 2. Cada entrada de abajo cita la frase que la respalda. Esta página del medicamento es un punto de partida, no un veredicto sobre su situación.

Interacciones según la etiqueta

Interacciones graves (131)

  • AclidinioanticolinérgicoGrave

    Avoid administrations of TUDORZA PRESSAIR with other anticholinergic-containing drugs. (etiqueta de Aclidinio, Interacciones medicamentosas)

  • AdrenalinasimpaticomiméticoGrave

    Other pressor agents, including epinephrine, should not be used because they may cause a paradoxical further lowering of blood pressure. (etiqueta de Proclorperazina, Precauciones)

  • AlcoholAlcoholGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • AlprazolambenzodiazepinaGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Amoxapinaantidepresivo tricíclicoGrave

    …the description of tardive dyskinesia and its clinical detection, please refer to the sections on Information for Patients and ADVERSE REACTIONS . ) Neuroleptic Malignant Syndrome (NMS) A potentially fatal symptom complex sometimes referred to as Neuroleptic Malignant Syndrome (NMS) has been reported in association with antipsychotic drugs and with amoxapine. (etiqueta de Amoxapina, Advertencias)

  • Articaína y adrenalinaanestésico localGrave

    Other pressor agents, including epinephrine, should not be used because they may cause a paradoxical further lowering of blood pressure. (etiqueta de Proclorperazina, Precauciones)

  • AtazanavirantirretroviralGrave

    …phenobarbital, phenytoin Antiarrhythmics Amiodarone (with ritonavir), quinidine (with ritonavir) Antimycobacterials Rifampin Antineoplastics Apalutamide, encorafenib, irinotecan, ivosidenib Antipsychotics Lurasidone (with ritonavir), pimozide Benzodiazepines Orally administered midazolam a , triazolam Ergot Derivatives Dihydroergotamine, ergonovine, ergotamine, methylergonovine… (etiqueta de Atazanavir, Contraindicaciones)

  • Azelastina y fluticasonaantihistamínicoGrave

    • Avoid concurrent use of alcohol or other central nervous system (CNS) depressants with azelastine hydrochloride and fluticasone propionate nasal spray because further decreased alertness and impairment of CNS performance may occur. (etiqueta de Azelastina y fluticasona, Advertencias y precauciones)

  • Baclofenorelajante muscularGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Belladona y opioopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Bromocriptinaagonista de la dopaminaGrave

    The concomitant use of CYCLOSET and dopamine receptor antagonists, including neuroleptic drugs, is not recommended. (etiqueta de Bromocriptina, Advertencias y precauciones)

  • Bupivacaína y adrenalinaanestésico localGrave

    Other pressor agents, including epinephrine, should not be used because they may cause a paradoxical further lowering of blood pressure. (etiqueta de Proclorperazina, Precauciones)

  • BuprenorfinaopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Butalbital y paracetamolbarbitúricoGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • ButorfanolopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • CarbamazepinaanticonvulsivoGrave

    CNS Depressants The concomitant use of EQUETRO and other CNS depressants can increase the risk of respiratory depression, profound sedation, hypotension, and syncope. (etiqueta de Carbamazepina, Interacciones medicamentosas)

  • CarbinoxaminaantihistamínicoGrave

    Avoid concurrent use of Carbinoxamine Maleate Extended-Release Oral Suspension with alcohol or other central nervous system depressants because additional impairment of central nervous system performance may occur. (etiqueta de Carbinoxamina, Advertencias y precauciones)

  • Carisoprodolrelajante muscularGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • CetirizinaantihistamínicoGrave

    Avoid concurrent use of QUZYTTIR with alcohol or other CNS depressants because additional reduction in alertness and additional impairment of CNS performance may occur. (etiqueta de Cetirizina, Advertencias y precauciones)

  • Ciclobenzaprinarelajante muscularGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • CiprofloxacinofluoroquinolonaGrave

    Table 8: Drugs That are Affected by and Affecting Ciprofloxacin Drugs That are Affected by Ciprofloxacin Drug(s) Recommendation Comments Tizanidine Contraindicated Concomitant administration of tizanidine and ciprofloxacin is contraindicated due to the potentiation of hypotensive and sedative effects of tizanidine [see Contraindications ( 4.2 )]. (etiqueta de Ciprofloxacino, Interacciones medicamentosas)

  • Citrato de potasiosuplemento de potasioGrave

    In patients in whom there is cause for arrest or delay in tablet passage through the gastrointestinal tract, such as those suffering from delayed gastric emptying, esophageal compression, intestinal obstruction or stricture, or those taking anticholinergic medication. (etiqueta de Citrato de potasio, Contraindicaciones)

  • Claritromicinaantibiótico macrólidoGrave

    Colchicine (in patients with normal renal and hepatic function) Use With Caution Antipsychotics: Pimozide Contraindicated Pimozide: [See Contraindications ( 4.2 )] Quetiapine Lurasidone Quetiapine: Quetiapine is a substrate for CYP3A4, which is inhibited by clarithromycin. (etiqueta de Claritromicina, Interacciones medicamentosas)

  • ClobazambenzodiazepinaGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • ClonazepambenzodiazepinaGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Clonidinaagonista alfa-adrenérgicoGrave

    Avoid use with other central nervous system (CNS) depressants ( 5.3 ) (etiqueta de Clonidina, Advertencias y precauciones)

  • ClorazepatobenzodiazepinaGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • ClordiazepóxidobenzodiazepinaGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Clordiazepóxido y clidiniobenzodiazepinaGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Clorzoxazonarelajante muscularGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • ClozapinaantipsicóticoGrave

    When possible, avoid concomitant use, with other anticholinergic medications because the risk for anticholinergic toxicity or severe gastrointestinal adverse reactions is increased [see Warnings and Precautions ( 5.7 ), Drug Interactions ( 7.1 )]. (etiqueta de Clozapina, Advertencias y precauciones)

  • CodeínaopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Dantrolenorelajante muscularGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Daridorexantsedante-hipnóticoGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • DarunavirantirretroviralGrave

    Alpha 1-adrenoreceptor antagonist: alfuzosin Anti-gout: colchicine, in patients with renal and/or hepatic impairment Antimycobacterial: rifampin Antipsychotics: lurasidone, pimozide Cardiac Disorders: dronedarone, ivabradine, ranolazine Ergot derivatives, e.g. dihydroergotamine, ergotamine, methylergonovine Herbal product: St. (etiqueta de Darunavir, Contraindicaciones)

  • Darunavir y cobicistatantirretroviralGrave

    …antagonist: alfuzosin Anticonvulsants: carbamazepine, phenobarbital, phenytoin Anti-gout: colchicine, in patients with renal and/or hepatic impairment Antimycobacterial: rifampin Antipsychotics: lurasidone, pimozide Cardiac Disorders: dronedarone, ivabradine, ranolazine Ergot derivatives, e.g. dihydroergotamine, ergotamine, methylergonovine Herbal product: St. (etiqueta de Darunavir y cobicistat, Contraindicaciones)

  • Deutetrabenazinainhibidor de VMAT2Grave

    Neuroleptic Malignant Syndrome (NMS) A potentially fatal symptom complex sometimes referred to as Neuroleptic Malignant Syndrome (NMS) has been reported in association with drugs that reduce dopaminergic transmission. (etiqueta de Deutetrabenazina, Advertencias y precauciones)

  • DiazepambenzodiazepinaGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • CONTRAINDICATIONS Diphenoxylate hydrochloride and atropine sulfate is contraindicated in: • Pediatric patients less than 6 years of age due to the risks of respiratory and central nervous system (CNS) depression (see WARNINGS ). (etiqueta de Difenoxilato y atropina, Contraindicaciones)

  • Usage of MOTOFEN ® in recommended doses is not likely to cause prominent anticholinergic side effects, but MOTOFEN ® should be avoided in patients in whom anticholinergic drugs are contraindicated. (etiqueta de Difenoxina y atropina, Advertencias)

  • DofetilidaantiarrítmicoGrave

    In addition, other known inhibitors of the renal cation transport system such as prochlorperazine, dolutegravir and megestrol should not be used in patients on dofetilide. (etiqueta de Dofetilida, Contraindicaciones)

  • Doxilamina y piridoxinaantihistamínicoGrave

    Central nervous system (CNS) depressants: Concurrent use with alcohol or other CNS depressants is not recommended ( 5.1 ) (etiqueta de Doxilamina y piridoxina, Advertencias y precauciones)

  • DronedaronaantiarrítmicoGrave

    …Clinical Pharmacology (12.3) ] • Concomitant use of drugs or herbal products that prolong the QT interval and might increase the risk of torsade de pointes, such as phenothiazine antipsychotics, tricyclic antidepressants, certain oral macrolide antibiotics, and Class I and III antiarrhythmics • Liver or lung toxicity related to the previous use of amiodarone… (etiqueta de Dronedarona, Contraindicaciones)

  • EluxadolinaopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Alpha 1-adrenoreceptor antagonist: alfuzosin Anticonvulsants: carbamazepine, phenobarbital, phenytoin Antimycobacterial: rifampin Antipsychotics: lurasidone, pimozide Ergot Derivatives: dihydroergotamine, ergotamine, methylergonovine Herbal Products: St. (etiqueta de Elvitegravir, cobicistat, emtricitabina y tenofovir, Contraindicaciones)

  • EstazolambenzodiazepinaGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Eszopiclonasedante-hipnóticoGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Fenelzinainhibidor de la MAOGrave

    Phenelzine sulfate should not be used in combination with dextromethorphan or with CNS depressants such as alcohol and certain narcotics. (etiqueta de Fenelzina, Contraindicaciones)

  • FenobarbitalbarbitúricoGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • FentaniloopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • FlumazenilobenzodiazepinaGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • FosamprenavirantirretroviralGrave

    …coadministered with the following drugs: Alpha 1-adrenoreceptor antagonist: Alfuzosin Antiarrhythmics: Flecainide (with ritonavir ), propafenone (with ritonavir ) Antimycobacterial: Rifampin Antipsychotic: Lurasidone (with ritonavir ), pimozide Ergot derivatives: Dihydroergotamine, ergonovine, ergotamine, methylergonovine GI motility agent: Cisapride Herbal product: St. (etiqueta de Fosamprenavir, Contraindicaciones)

  • GabapentinaanticonvulsivoGrave

    • Respiratory Depression: May occur with NEURONTIN when used with concomitant central nervous system (CNS) depressants, including opioids, or in the setting of underlying respiratory impairment. (etiqueta de Gabapentina, Advertencias y precauciones)

  • GlicopirronioanticolinérgicoGrave

    • Other Conditions Exacerbated by Anticholinergic Adverse Reactions : Use is not recommended in patients with autonomic neuropathy, hyperthyroidism, cardiac disease, hiatal hernia, etc. (etiqueta de Glicopirronio, Advertencias y precauciones)

  • Intervention Concomitant use of anticholinergic drugs with GVOKE VialDx is not recommended. (etiqueta de Glucagón, Interacciones medicamentosas)

  • HidrocodonaopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • HidromorfonaopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • HidroxizinaantihistamínicoGrave

    Rarely, cardiac arrests and death have been reported in association with the combined use of hydroxyzine hydrochloride intramuscularly and other CNS depressants. (etiqueta de Hidroxizina, Precauciones)

  • IpratropioanticolinérgicoGrave

    Avoid administration of ATROVENT HFA with other anticholinergic-containing drugs ( 7.1 ) (etiqueta de Ipratropio, Interacciones medicamentosas)

  • Ketaminadepresor del SNCGrave

    Benzodiazepines, Opioid Analgesics, or other CNS Depressants : Concomitant use may result in profound sedation, respiratory depression, coma, or death. (etiqueta de Ketamina, Interacciones medicamentosas)

  • Ketoconazolantifúngico azólicoGrave

    This may potentiate and prolong hypnotic and sedative effects, especially with repeated dosing or chronic administration of these agents. (etiqueta de Ketoconazol, Contraindicaciones)

  • Lemborexantsedante-hipnóticoGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • LevocetirizinaantihistamínicoGrave

    Avoid concurrent use of alcohol or other central nervous system depressants with XYZAL. (etiqueta de Levocetirizina, Advertencias y precauciones)

  • LevorfanolopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Lidocaína y adrenalinaanestésico localGrave

    Other pressor agents, including epinephrine, should not be used because they may cause a paradoxical further lowering of blood pressure. (etiqueta de Proclorperazina, Precauciones)

  • Lopinavir y ritonavirantirretroviralGrave

    Alpha 1- Adrenoreceptor Antagonist: alfuzosin Antianginal: ranolazine Antiarrhythmic: dronedarone Anti-gout: colchicine Antipsychotics: lurasidone, pimozide Ergot Derivatives: dihydroergotamine, ergotamine, methylergonovine GI Motility Agent: cisapride Hepatitis C direct acting antiviral: elbasvir/grazoprevir HMG-CoA Reductase Inhibitors: lovastatin, simvastatin… (etiqueta de Lopinavir y ritonavir, Contraindicaciones)

  • LorazepambenzodiazepinaGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • LumateperonaantipsicóticoGrave

    Agranulocytosis (including fatal cases) has been reported with other antipsychotic drugs. (etiqueta de Lumateperona, Advertencias y precauciones)

  • MetadonaopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Metaxalonarelajante muscularGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Metocarbamolrelajante muscularGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Metoclopramidaantagonista de la dopaminaGrave

    • Tardive Dyskinesia (TD), Other Extrapyramidal Symptoms (EPS), and Neuroleptic Malignant Syndrome (NMS) : Avoid concomitant use of other drugs known to cause TD/EPS/NMS and avoid use in patients with Parkinson’s Disease. (etiqueta de Metoclopramida, Advertencias y precauciones)

  • MetohexitalbarbitúricoGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • MidazolambenzodiazepinaGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • MorfinaopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • NalbufinaopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Nalmefenoantagonista opioideGrave

    Risk of Recurrent Respiratory and CNS Depression : A recurrence of respiratory depression is possible, therefore, keep the patient under continued surveillance and administer repeat doses of ZURNAI using a new auto-injector with each dose while awaiting emergency medical assistance. (etiqueta de Nalmefeno, Advertencias y precauciones)

  • …Antiarrhythmic: amiodarone, dronedarone, flecainide, propafenone, quinidine • Anti-gout: colchicine (in patients with renal and/or hepatic impairment [see Table 2 , Drug Interactions (7.3)] ) • Antipsychotics: lurasidone, pimozide • Benign prostatic hyperplasia agents: silodosin • Cardiovascular agents: eplerenone, ivabradine • Ergot derivatives: dihydroergotamine, ergotamine,… (etiqueta de Nirmatrelvir y ritonavir, Contraindicaciones)

  • OliceridinaopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • OlopatadinaantihistamínicoGrave

    • Avoid concurrent use of alcohol or other central nervous system depressants with olopatadine hydrochloride nasal solution (nasal spray) ( 5.2 ). (etiqueta de Olopatadina, Advertencias y precauciones)

  • Olopatadina y mometasonaantihistamínicoGrave

    • Avoid concurrent use of alcohol or other central nervous system (CNS) depressants with RYALTRIS because additional reductions in alertness and additional impairment of CNS performance may occur. (etiqueta de Olopatadina y mometasona, Advertencias y precauciones)

  • Orfenadrinarelajante muscularGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • OxazepambenzodiazepinaGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Oxibato de sodiodepresor del SNCGrave

    • Central Nervous System Depression Xyrem (sodium oxybate) is a CNS depressant. (etiqueta de Oxibato de sodio, Advertencia en recuadro)

  • OxicodonaopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • OximorfonaopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • PregabalinaanticonvulsivoGrave

    • Respiratory Depression : May occur with LYRICA when used with concomitant CNS depressants or in the setting of underlying respiratory impairment. (etiqueta de Pregabalina, Advertencias y precauciones)

  • Prilocaína y adrenalinaanestésico localGrave

    Other pressor agents, including epinephrine, should not be used because they may cause a paradoxical further lowering of blood pressure. (etiqueta de Proclorperazina, Precauciones)

  • PrimidonaanticonvulsivoGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • QuinidinaantiarrítmicoGrave

    Quinidine is also contraindicated in patients who, like those with myasthenia gravis, might be adversely affected by an anticholinergic agent. (etiqueta de Quinidina, Contraindicaciones)

  • Ramelteónsedante-hipnóticoGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • RemifentaniloopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • RifampicinaantibióticoGrave

    …Concomitant use of clopidogrel and rifampin should be discouraged Increase active metabolite exposure and risk of bleeding Ticagrelor Prevention or Management: Avoid use Decrease exposure Antipsychotics Haloperidol Decrease plasma concentrations by 70% Lurasidone Prevention or Management: Concomitant use is contraindicated (See CONTRAINDICATIONS ) Decrease exposure Oral… (etiqueta de Rifampicina, Interacciones medicamentosas)

  • RitonavirantirretroviralGrave

    WARNING: DRUG-DRUG INTERACTIONS LEADING TO POTENTIALLY SERIOUS AND/OR LIFE THREATENING REACTIONS Co-administration of NORVIR with several classes of drugs including sedative hypnotics, antiarrhythmics, or ergot alkaloid preparations may result in potentially serious and/or life-threatening adverse events due to possible effects of NORVIR on the hepatic metabolism… (etiqueta de Ritonavir, Advertencia en recuadro)

  • Rivastigminainhibidor de la colinesterasaGrave

    Concomitant use with metoclopramide, beta-blockers, or cholinomimetic and anticholinergic drugs is not recommended ( 7.1 , 7.2 , 7.3 ) (etiqueta de Rivastigmina, Interacciones medicamentosas)

  • Suvorexantsedante-hipnóticoGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • TapentadolopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Tasimelteónsedante-hipnóticoGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • TemazepambenzodiazepinaGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Tetrabenazinainhibidor de VMAT2Grave

    Neuroleptic Malignant Syndrome (NMS) A potentially fatal symptom complex sometimes referred to as Neuroleptic Malignant Syndrome (NMS) has been reported in association with tetrabenazine tablets and other drugs that reduce dopaminergic transmission [see Drug Interactions (7.6) ]. (etiqueta de Tetrabenazina, Advertencias y precauciones)

  • TioridazinaantipsicóticoGrave

    …proarrhythmic effects, thioridazine should be reserved for use in the treatment of schizophrenic patients who fail to show an acceptable response to adequate courses of treatment with other antipsychotic drugs, either because of insufficient effectiveness or the inability to achieve an effective dose due to intolerable adverse effects from those drugs (see WARNINGS , CONTRAINDICATIONS… (etiqueta de Tioridazina, Advertencia en recuadro)

  • TiotropioanticolinérgicoGrave

    Avoid administration of SPIRIVA RESPIMAT with other anticholinergic-containing drugs. (etiqueta de Tiotropio, Interacciones medicamentosas)

  • Tizanidinarelajante muscularGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • TramadolopioideGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • Tranilciprominainhibidor de la MAOGrave

    …(HR) b or Serotonin Syndrome (SS) c ] Agents with blood pressure-reducing effects Use with caution d Hypotension e Non-selective H1 receptor antagonists Contraindicated a Increased anticholinergic effects Beta-adrenergic blockers (see also agents or procedures with blood pressure-reducing effects) Use with the caution d More pronounced bradycardia, postural hypotension… (etiqueta de Tranilcipromina, Interacciones medicamentosas)

  • TriazolambenzodiazepinaGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • TrihexifenidiloanticolinérgicoGrave

    Neuroleptic Malignant Syndrome A potentially fatal symptom complex sometimes referred to as Neuroleptic Malignant Syndrome (NMS) has been reported in association with dose reduction or discontinuation of trihexyphenidyl. (etiqueta de Trihexifenidilo, Advertencias)

  • Avoid trimethobenzamide hydrochloride capsules in patients receiving other drugs that are likely to cause EPS (e.g. antipsychotics) [see Drug Interactions (7.2) ] . (etiqueta de Trimetobenzamida, Advertencias y precauciones)

  • UmeclidinioanticolinérgicoGrave

    Avoid administration of Umeclidinium ELLIPTA with other anticholinergic-containing drugs. (etiqueta de Umeclidinio, Interacciones medicamentosas)

  • Umeclidinio y vilanterolanticolinérgicoGrave

    Avoid administration of Umeclidinium and Vilanterol ELLIPTA with other anticholinergic-containing drugs. (etiqueta de Umeclidinio y vilanterol, Interacciones medicamentosas)

  • Valbenazinainhibidor de VMAT2Grave

    Neuroleptic Malignant Syndrome (NMS ) A potentially fatal symptom complex referred to as Neuroleptic Malignant Syndrome (NMS) has been reported in association with drugs that reduce dopaminergic transmission. (etiqueta de Valbenazina, Advertencias y precauciones)

  • Zaleplónsedante-hipnóticoGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

  • ZiprasidonaantipsicóticoGrave

    As with other antipsychotic drugs and placebo, sudden unexplained deaths have been reported in patients taking ziprasidone at recommended doses. (etiqueta de Ziprasidona, Advertencias y precauciones)

  • Zolpidemsedante-hipnóticoGrave

    Do not use in comatose states or in the presence of large amounts of central nervous system depressants (alcohol, barbiturates, narcotics, etc.). Do not use in pediatric surgery. (etiqueta de Proclorperazina, Contraindicaciones)

Interacciones moderadas (164)

  • Acetazolamidainhibidor de la anhidrasa carbónicaModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Ácido etacrínicodiurético de asaModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Ácido valproicoanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • Alopurinolinhibidor de la xantina oxidasaModerada

    Inform patients also that the central nervous system depressant effects of allopurinol tablets may be additive to those of alcohol and other CNS depressants. (etiqueta de Alopurinol, Advertencias y precauciones)

  • Amiloridadiurético ahorrador de potasioModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • AminofilinametilxantinaModerada

    25% increase Diazepam Benzodiazepines increase CNS concentrations of adenosine, a potent CNS depressant, while theophylline blocks adenosine receptors. (etiqueta de Aminofilina, Interacciones medicamentosas)

  • AripiprazolantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • AsenapinaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • Atenolol y clortalidonabetabloqueanteModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Benazepril e hidroclorotiazidainhibidor de la ECAModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Sedatives/Hypnotics: midazolam (oral) triazolam ↑ midazolam (oral) ↑ triazolam Use caution when midazolam or triazolam is concomitantly administered with BIXLENVO. (etiqueta de Bictegravir, emtricitabina y tenofovir alafenamida, Interacciones medicamentosas)

  • Bisoprolol e hidroclorotiazidabetabloqueanteModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • BrexpiprazolantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • Brimonidinaagonista alfa-adrenérgicoModerada

    Use with CNS depressants may result in an additive or potentiating effect. (etiqueta de Brimonidina, Interacciones medicamentosas)

  • Brimonidina y timololagonista alfa-adrenérgicoModerada

    Use with CNS depressants may result in an additive or potentiating effect. (etiqueta de Brimonidina y timolol, Interacciones medicamentosas)

  • BrivaracetamanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • Central Nervous System (CNS) depressants Antihistamines have additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, antianxiety agents, etc.). Antihypertensive drugs Sympathomimetic may reduce the effects of antihypertensive drugs. (etiqueta de Bromfeniramina, pseudoefedrina y dextrometorfano, Interacciones medicamentosas)

  • Bumetanidadiurético de asaModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Bupivacaínaanestésico localModerada

    Possible early warning signs of central nervous system (CNS) toxicity are restlessness, anxiety, incoherent speech, lightheadedness, numbness and tingling of the mouth and lips, metallic taste, tinnitus, dizziness, blurred vision, tremors, twitching, CNS depression, or drowsiness. (etiqueta de Bupivacaína, Advertencias y precauciones)

  • BupropiónantidepresivoModerada

    The following conditions can also increase the risk of seizure: concomitant use of other medications that lower the seizure threshold (e.g., other bupropion products, antipsychotics, tricyclic antidepressants, theophylline, and systemic corticosteroids), metabolic disorders (e.g., hypoglycemia, hyponatremia, severe hepatic impairment, and hypoxia), or use of… (etiqueta de Bupropión, Advertencias y precauciones)

  • Buspironafármaco serotoninérgicoModerada

    Triazolam/flurazepam: Coadministration of buspirone with either triazolam or flurazepam did not appear to prolong or intensify the sedative effects of either benzodiazepine. (etiqueta de Buspirona, Interacciones medicamentosas)

  • Candesartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Cannabidiol (con receta)anticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • CarbidopaModerada

    Hyperpyrexia and Confusion Sporadic cases of a symptom complex resembling neuroleptic malignant syndrome (NMS) have been reported in association with dose reductions or withdrawal of certain antiparkinsonian agents such as levodopa, carbidopa-levodopa, or carbidopa-levodopa extended release. (etiqueta de Carbidopa, Advertencias)

  • Carbidopa y levodopafármaco dopaminérgicoModerada

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etiqueta de Carbidopa y levodopa, Advertencias y precauciones)

  • Carbidopa, levodopa y entacaponafármaco dopaminérgicoModerada

    Withdrawal-Emergent Hyperpyrexia and Confusion Cases of hyperpyrexia and confusion resembling neuroleptic malignant syndrome (NMS) have been reported in association with dose reduction or withdrawal of therapy with carbidopa, levodopa and entacapone. (etiqueta de Carbidopa, levodopa y entacapona, Advertencias y precauciones)

  • CariprazinaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • CenobamatoanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • CiproheptadinaantihistamínicoModerada

    CNS Depressants Antihistamines may have additive effects with alcohol and other CNS depressants, e.g., hypnotics, sedatives, tranquilizers, antianxiety agents. (etiqueta de Ciproheptadina, Advertencias)

  • CitalopramISRSModerada

    Such drugs include Class 1A (e.g., quinidine, procainamide) or Class III (e.g., amiodarone, sotalol) antiarrhythmic medications, antipsychotic medications (e.g., chlorpromazine, thioridazine), antibiotics (e.g., gatifloxacin, moxifloxacin), or any other class of medications known to prolong the QTc interval (e.g., pentamidine, levomethadyl acetate, methadone). (etiqueta de Citalopram, Advertencias y precauciones)

  • ClemastinaantihistamínicoModerada

    Use with CNS Depressants Clemastine has additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, etc.). Use in Activities Requiring Mental Alertness Patients should be warned about engaging in activities requiring mental alertness such as driving a car or operating appliances, machinery, etc. (etiqueta de Clemastina, Advertencias)

  • Clorotiazidadiurético tiazídicoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • ClorpromazinaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • Clortalidonadiurético tiazídicoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • DarifenacinaanticolinérgicoModerada

    Darifenacin extended-release tablets, like other anticholinergic drugs, may decrease gastrointestinal motility and should be used with caution in patients with conditions such as severe constipation, ulcerative colitis, and myasthenia gravis. (etiqueta de Darifenacina, Advertencias y precauciones)

  • Desfluranoanestésico generalModerada

    Phenothiazines may intensify or prolong the action of central nervous system depressants (e.g., alcohol, anesthetics, narcotics). (etiqueta de Proclorperazina, Advertencias)

  • DexclorfeniraminaantihistamínicoModerada

    Use with CNS Depressants CORPHENA Oral Solution has additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, etc.). Use in Activities Requiring Mental Alertness Patients should be warned about engaging in activities requiring mental alertness such as driving a car or operating appliances, machinery, etc. (etiqueta de Dexclorfeniramina, Advertencias)

  • Dexmedetomidinaagonista alfa-adrenérgicoModerada

    The intravenous administration of anticholinergic agents (e.g., glycopyrrolate, atropine) should be considered to modify vagal tone. (etiqueta de Dexmedetomidina, Advertencias y precauciones)

  • Dextrometorfano y quinidinafármaco serotoninérgicoModerada

    Anticholinergic effects of quinidine: Monitor for worsening in myasthenia gravis and other sensitive conditions. (etiqueta de Dextrometorfano y quinidina, Advertencias y precauciones)

  • DicicloverinaanticolinérgicoModerada

    Anticholinergic agents: may affect the gastrointestinal absorption of various drugs; may also increase certain actions or side effects of other anticholinergic drugs (7) (etiqueta de Dicicloverina, Interacciones medicamentosas)

  • DifenhidraminaantihistamínicoModerada

    Drug Interactions Diphenhydramine hydrochloride has additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, etc). (etiqueta de Difenhidramina, Interacciones medicamentosas)

  • DimenhidrinatoantihistamínicoModerada

    The concomitant use of alcohol or other central nervous system depressants may have an additive effect. (etiqueta de Dimenhidrinato, Advertencias)

  • Divalproato de sodio (valproato)anticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • Doxepinaantidepresivo tricíclicoModerada

    Potential additive effects when used in combination with CNS depressants or sedating antihistamines. (etiqueta de Doxepina, Advertencias y precauciones)

  • DronabinolcannabinoideModerada

    Concomitant use of other drugs that cause dizziness, confusion, sedation, or somnolence such as CNS depressants may increase this effect (e.g., barbiturates, benzodiazepines, lithium, opioids, buspirone, scopolamine, antihistamines, tricyclic antidepressants, other anticholinergic agents, and muscle relaxants). (etiqueta de Dronabinol, Advertencias y precauciones)

  • Droperidolantagonista de la dopaminaModerada

    Since it may be difficult to distinguish neuroleptic malignant syndrome from malignant hyperpyrexia in the perioperative period, prompt treatment with dantrolene should be considered if increases in temperature, heart rate or carbon dioxide production occur. (etiqueta de Droperidol, Advertencias)

  • DroxidopasimpaticomiméticoModerada

    Observe patients carefully when the dosage of NORTHERA is changed or when concomitant levodopa is reduced abruptly or discontinued, especially if the patient is receiving neuroleptics. (etiqueta de Droxidopa, Advertencias y precauciones)

  • Enalapril e hidroclorotiazidainhibidor de la ECAModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Eplerenonaantagonista de la aldosteronaModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • EscopolaminaanticolinérgicoModerada

    • Gastrointestinal and Urinary Disorders : Consider more frequent monitoring during treatment in patients suspected of having intestinal obstruction; patients with pyloric obstruction, patients with impeded urine flow or receiving other anticholinergic drugs. (etiqueta de Escopolamina, Advertencias y precauciones)

  • EslicarbazepinaanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • Espironolactonaantagonista de la aldosteronaModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Espironolactona e hidroclorotiazidaantagonista de la aldosteronaModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Etomidatoanestésico generalModerada

    Phenothiazines may intensify or prolong the action of central nervous system depressants (e.g., alcohol, anesthetics, narcotics). (etiqueta de Proclorperazina, Advertencias)

  • EtosuximidaanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • FelbamatoanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • FenitoínaanticonvulsivoModerada

    However, it has been reported that phenothiazines may interfere with the metabolism of Dilantin ® ‡ and thus precipitate Dilantin toxicity. (etiqueta de Proclorperazina, Precauciones)

  • Fentermina y topiramatoestimulante del SNCModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • FesoterodinaanticolinérgicoModerada

    Urinary Retention in Adult Patients With Bladder Outlet Obstruction The use of Toviaz, like other antimuscarinic drugs, in patients with clinically significant bladder outlet obstruction, including patients with urinary retention, may result in further urinary retention and kidney injury. (etiqueta de Fesoterodina, Advertencias y precauciones)

  • Flibanserinadepresor del SNCModerada

    Exacerbated by other CNS depressants, and in settings where flibanserin concentrations are increased. (etiqueta de Flibanserina, Advertencias y precauciones)

  • FlufenazinaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • FluoxetinaISRSModerada

    Coadministration of fluoxetine with other drugs that are metabolized by CYP2D6, including certain antidepressants (e.g., TCAs), antipsychotics (e.g., phenothiazines and most atypicals), and antiarrhythmics (e.g., propafenone, flecainide, and others) should be approached with caution. (etiqueta de Fluoxetina, Interacciones medicamentosas)

  • FluvoxaminaISRSModerada

    CNS Active Drugs Antipsychotics: See Warnings and Precautions ( 5.2 ) . (etiqueta de Fluvoxamina, Interacciones medicamentosas)

  • FosfenitoínaanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • FosfomicinaantibióticoModerada

    Avoid co-administration of CONTEPO with drugs known to prolong the QT interval, such as class IA or class III antiarrhythmic medications, tricyclic antidepressants, macrolides, and antipsychotics [see Warnings and Precautions ( 5.2 )] . (etiqueta de Fosfomicina, Interacciones medicamentosas)

  • Fosinopril e hidroclorotiazidainhibidor de la ECAModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Furosemidadiurético de asaModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • GlimepiridasulfonilureaModerada

    …medications that may reduce the glucose-lowering effect of sulfonylureas including glimepiride, leading to worsening glycemic control: danazol, glucagon, somatropin, protease inhibitors, atypical antipsychotic medications (e.g., olanzapine and clozapine), barbiturates, diazoxide, laxatives, rifampin, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid… (etiqueta de Glimepirida, Interacciones medicamentosas)

  • GlipizidasulfonilureaModerada

    The following are examples of medication that may reduce the glucose-lowering effect of GLUCOTROL XL, leading to worsening glycemic control: atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease… (etiqueta de Glipizida, Interacciones medicamentosas)

  • Guanfacinaagonista alfa-adrenérgicoModerada

    Consider the potential for additive sedative effects with CNS depressant drugs. (etiqueta de Guanfacina, Advertencias y precauciones)

  • HaloperidolantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • Hidroclorotiazidadiurético tiazídicoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • IloperidonaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • Imipraminaantidepresivo tricíclicoModerada

    Imipramine hydrochloride may enhance the CNS depressant effects of alcohol. (etiqueta de Imipramina, Advertencias)

  • Indapamidadiurético tiazídicoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Insulina aspartainsulinaModerada

    Drugs That May Decrease the Blood Glucose Lowering Effect of Insulin Aspart Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g.,… (etiqueta de Insulina asparta, Interacciones medicamentosas)

  • Insulina degludecinsulinaModerada

    Drugs That May Decrease the Blood Glucose Lowering Effect of Insulin Degludec Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g.,… (etiqueta de Insulina degludec, Interacciones medicamentosas)

  • Insulina detemirinsulinaModerada

    Drugs That May Decrease the Blood Glucose Lowering Effect of LEVEMIR Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol,… (etiqueta de Insulina detemir, Interacciones medicamentosas)

  • Insulina glarginainsulinaModerada

    Drugs that May Decrease the Blood Glucose Lowering Effect of Insulin Glargine-yfgn Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents… (etiqueta de Insulina glargina, Interacciones medicamentosas)

  • Insulina lisproinsulinaModerada

    Drugs That May Decrease the Blood Glucose Lowering Effect of LYUMJEV Drugs: Atypical antipsychotics (e.g., olanzapine and clozapine), corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol,… (etiqueta de Insulina lispro, Interacciones medicamentosas)

  • Ipratropio y salbutamolanticolinérgicoModerada

    Caution is, therefore, advised in the co-administration of Ipratropium Bromide and Albuterol Sulfate Inhalation Solution with other drugs having anticholinergic properties. β-adrenergic agents Caution is advised in the co-administration of Ipratropium Bromide and Albuterol Sulfate Inhalation Solution and other sympathomimetic agents due to the increased risk… (etiqueta de Ipratropio y salbutamol, Interacciones medicamentosas)

  • Irbesartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Isofluranoanestésico generalModerada

    Phenothiazines may intensify or prolong the action of central nervous system depressants (e.g., alcohol, anesthetics, narcotics). (etiqueta de Proclorperazina, Advertencias)

  • Itraconazolantifúngico azólicoModerada

    Antipsychotics, Anxiolytics and Hypnotics Alprazolam Aripiprazole Buspirone Diazepam Haloperidol Midazolam (IV) Quetiapine Ramelteon Risperidone Suvorexant Monitor for adverse reactions. (etiqueta de Itraconazol, Interacciones medicamentosas)

  • LacosamidaanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • LamotriginaanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • LevetiracetamanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • Levodopafármaco dopaminérgicoModerada

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex that resembles neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in dopaminergic therapy. (etiqueta de Levodopa, Advertencias y precauciones)

  • Lisinopril e hidroclorotiazidainhibidor de la ECAModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Litiofármaco serotoninérgicoModerada

    Because of a possible causal relationship between these events and the concomitant administration of lithium and antipsychotics, patients receiving such combined therapy should be monitored closely for early evidence of neurologic toxicity and treatment discontinued promptly if such signs appear. (etiqueta de Proclorperazina, Advertencias)

  • Lofexidinaagonista alfa-adrenérgicoModerada

    Increased Risk of CNS Depression with Concomitant use of CNS Depressant Drugs : Lofexidine tablets potentiates the CNS depressant effects of benzodiazepines and may potentiate the CNS depressant effects of alcohol, barbiturates, and other sedating drugs. (etiqueta de Lofexidina, Advertencias y precauciones)

  • Loperamidafármaco que prolonga el intervalo QTModerada

    …others drugs or herbal products that are known to prolong the QT interval, including Class 1A (e.g., quinidine, procainamide) or Class III (e.g., amiodarone, sotalol) antiarrhythmics, antipsychotics (e.g., chlorpromazine, haloperidol, thioridazine, ziprasidone), antibiotics (e.g., moxifloxacin), or any other drug known to prolong the QT interval (e.g., pentamidine,… (etiqueta de Loperamida, Advertencias)

  • Losartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • LoxapinaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • LurasidonaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • MeclozinaantihistamínicoModerada

    • Coadministration of meclizine hydrochloride with other CNS depressants, including alcohol, may result in increased CNS depression ( 7.1 ). (etiqueta de Meclozina, Interacciones medicamentosas)

  • Meprobamatodepresor del SNCModerada

    Additive Effects Since the effects of meprobamate and alcohol or meprobamate and other CNS depressants or psychotropic drugs may be additive,appropriate caution should be exercised with patients who take more than one of these agents simultaneously. (etiqueta de Meprobamato, Advertencias)

  • MesuximidaanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • MetilescopolaminaanticolinérgicoModerada

    Drug interactions Additive anticholinergic effects may result from concomitant use with antipsychotics, tricyclic antidepressants, and other drugs with anticholinergic effects. (etiqueta de Metilescopolamina, Interacciones medicamentosas)

  • MetirosinaModerada

    Concurrent use of metyrosine with alcohol or other CNS depressants can increase their sedative effects. (etiqueta de Metirosina, Interacciones medicamentosas)

  • Metolazonadiurético tiazídicoModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Metoprolol e hidroclorotiazidabetabloqueanteModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Mirabegrónagonista beta-adrenérgicoModerada

    • Urinary Retention in Patients With Bladder Outlet Obstruction and in Patients Taking Muscarinic Antagonist Drugs for Overactive Bladder : Administer with caution in these patients because of risk of urinary retention. (etiqueta de Mirabegrón, Advertencias y precauciones)

  • MoxifloxacinofluoroquinolonaModerada

    Pharmacokinetic studies between moxifloxacin and other drugs that prolong the QT interval such as cisapride, erythromycin, antipsychotics, and tricyclic antidepressants have not been performed. (etiqueta de Moxifloxacino, Advertencias y precauciones)

  • Naloxonaantagonista opioideModerada

    WARNINGS AND PRECAUTIONS Risk of Recurrent Respiratory and CNS Depression : Due to the duration of action of naloxone relative to the opioid, respiratory and CNS depression may recur after the first dose of naloxone. (etiqueta de Naloxona, Advertencias y precauciones)

  • Naltrexona y bupropiónantagonista opioideModerada

    …medications (sulfonylureas and meglitinides) that may cause hypoglycemia concomitant administration of medications that may lower the seizure threshold, including other bupropion products, antipsychotics, tricyclic antidepressants, theophylline, systemic steroids Recommendations for Reducing the Risk of Seizure: Clinical experience with bupropion suggests that the risk… (etiqueta de Naltrexona y bupropión, Advertencias y precauciones)

  • Neostigminainhibidor de la colinesterasaModerada

    An anticholinergic agent, (e.g., atropine sulfate or glycopyrrolate) should be administered prior to Neostigmine Methylsulfate Injection administration to lessen the risk of bradycardia [ see Dosage and Administration ( 2.4 ) ]. (etiqueta de Neostigmina, Advertencias y precauciones)

  • Nortriptilinaantidepresivo tricíclicoModerada

    Close supervision and careful adjustment of the dosage are required when Pamelor is used with other anticholinergic drugs and sympathomimetic drugs. (etiqueta de Nortriptilina, Interacciones medicamentosas)

  • OlanzapinaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • Olanzapina y fluoxetinaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • Olmesartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Olmesartán, amlodipino e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • OxcarbazepinaanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • OxibutininaanticolinérgicoModerada

    Oxybutynin chloride extended-release tablets, like other anticholinergic drugs, may decrease gastrointestinal motility and should be used with caution in patients with conditions such as ulcerative colitis and intestinal atony. (etiqueta de Oxibutinina, Advertencias y precauciones)

  • PaliperidonaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • PerampanelanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • PerfenazinaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • Pilocarpinaagonista colinérgicoModerada

    These effects should be considered when anticholinergic properties may be contributing to the therapeutic effect of concomitant medication (e.g., atropine, inhaled ipratropium). (etiqueta de Pilocarpina, Interacciones medicamentosas)

  • PimavanserinaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • PimozidaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • Pioglitazona y glimepiridatiazolidinedionaModerada

    …medications that may reduce the glucose-lowering effect of sulfonylureas including glimepiride, leading to worsening glycemic control: danazol, glucagon, somatropin, protease inhibitors, atypical antipsychotic medications (e.g., olanzapine and clozapine), barbiturates, diazoxide, laxatives, rifampin, thiazides and other diuretics, corticosteroids, phenothiazines, thyroid… (etiqueta de Pioglitazona y glimepirida, Interacciones medicamentosas)

  • Piridostigminainhibidor de la colinesterasaModerada

    Use with caution in persons with increased risk of anticholinergic reactions, such as persons with bronchial asthma, chronic obstructive pulmonary disease, bradycardia, cardiac arrhythmias, beta blocker treatment (increased risk of anticholinergic reactions). (etiqueta de Piridostigmina, Advertencias y precauciones)

  • Posaconazolantifúngico azólicoModerada

    Concomitant Use with Midazolam : Noxafil can prolong hypnotic/sedative effects. (etiqueta de Posaconazol, Advertencias y precauciones)

  • Pramipexolagonista de la dopaminaModerada

    Hyperpyrexia and Confusion Although not reported with pramipexole in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction,… (etiqueta de Pramipexol, Advertencias y precauciones)

  • ProcainamidaantiarrítmicoModerada

    Anticholinergic drugs administered concurrently with PA may produce additive antivagal effects on A-V nodal conduction, although this is not as well documented for PA as for quinidine. (etiqueta de Procainamida, Interacciones medicamentosas)

  • PrometazinaantihistamínicoModerada

    The impairment may be amplified by concomitant use of other central-nervous-system depressants such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers; therefore such agents should either be eliminated or given in reduced dosage in the presence of promethazine… (etiqueta de Prometazina, Advertencias)

  • Prometazina y dextrometorfanoantihistamínicoModerada

    The impairment may be amplified by concomitant use of other central-nervous-system depressants such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers; therefore such agents should either be eliminated or given in reduced dosage in the presence of promethazine… (etiqueta de Prometazina y dextrometorfano, Advertencias)

  • Propofoldepresor del SNCModerada

    Phenothiazines may intensify or prolong the action of central nervous system depressants (e.g., alcohol, anesthetics, narcotics). (etiqueta de Proclorperazina, Advertencias)

  • PropranololbetabloqueanteModerada

    Concomitant administration of propranolol with phenothiazines results in increased plasma levels of both drugs. (etiqueta de Proclorperazina, Precauciones)

  • Protriptilinaantidepresivo tricíclicoModerada

    Protriptyline may enhance the response to alcohol and the effects of barbiturates and other CNS depressants. (etiqueta de Protriptilina, Interacciones medicamentosas)

  • QuetiapinaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • Quinapril e hidroclorotiazidainhibidor de la ECAModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Ranolazinafármaco que prolonga el intervalo QTModerada

    Drugs Metabolized by CYP2D6 The exposure to CYP2D6 substrates, such as tricyclic antidepressants and antipsychotics, may be increased during co-administration with ASPRUZYO Sprinkle, and lower doses of these drugs may be required. (etiqueta de Ranolazina, Interacciones medicamentosas)

  • Rasagilinainhibidor de la MAOModerada

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction, withdrawal of, or changes in drugs that increase central… (etiqueta de Rasagilina, Advertencias y precauciones)

  • RifapentinaantibióticoModerada

    …doxycycline; Fluoroquinolones (such as ciprofloxacin) Oral Anticoagulants Warfarin Anticonvulsants Phenytoin Antimalarials Quinine Azole Antifungals Fluconazole, itraconazole, ketoconazole Antipsychotics Haloperidol Barbiturates Phenobarbital Benzodiazepines Diazepam Beta-Blockers Propranolol Calcium Channel Blockers Diltiazem, nifedipine, verapamil Cardiac Glycoside… (etiqueta de Rifapentina, Interacciones medicamentosas)

  • RisperidonaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • Ropinirolagonista de la dopaminaModerada

    Withdrawal-Emergent Hyperpyrexia and Confusion A symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with rapid dose reduction of, withdrawal of, or changes in, dopaminergic therapy. (etiqueta de Ropinirol, Advertencias y precauciones)

  • RufinamidaanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • Selegilinainhibidor de la MAOModerada

    Withdrawal Emergent Hyperpyrexia and Confusion Although not reported with ZELAPAR in the clinical development program, a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, altered consciousness, and autonomic instability), with no other obvious etiology, has been reported in association with… (etiqueta de Selegilina, Advertencias y precauciones)

  • Sevofluranoanestésico generalModerada

    Phenothiazines may intensify or prolong the action of central nervous system depressants (e.g., alcohol, anesthetics, narcotics). (etiqueta de Proclorperazina, Advertencias)

  • SolifenacinaanticolinérgicoModerada

    Urinary Retention The use of Solifenacin succinate tablets, like other antimuscarinic drugs, in patients with clinically significant bladder outlet obstruction including patients with urinary retention, may result in further urinary retention and kidney injury. (etiqueta de Solifenacina, Advertencias y precauciones)

  • SugammadexModerada

    Monitor for hemodynamic changes and administer anticholinergic agents such as atropine if clinically significant bradycardia is observed. (etiqueta de Sugammadex, Advertencias y precauciones)

  • Suxametonio (succinilcolina)bloqueador neuromuscularModerada

    Pretreatment with anticholinergic agents (e.g., atropine) may reduce the occurrence of bradyarrhythmias. (etiqueta de Suxametonio (succinilcolina), Advertencias y precauciones)

  • Telmisartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • TeofilinametilxantinaModerada

    25% increase Diazepam Benzodiazepines increase CNS concentrations of adenosine, a potent CNS depressant, while theophylline blocks adenosine receptors. (etiqueta de Teofilina, Interacciones medicamentosas)

  • TiagabinaanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • TiotixenoantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • TolcaponaModerada

    Hyperpyrexia and Confusion: In clinical trials, four cases of a symptom complex resembling the neuroleptic malignant syndrome (characterized by elevated temperature, muscular rigidity, and altered consciousness), similar to that reported in association with the rapid dose reduction or withdrawal of other dopaminergic drugs, have been reported in association with… (etiqueta de Tolcapona, Precauciones)

  • TopiramatoanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • Torasemidadiurético de asaModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Toremifenomodulador selectivo de los receptores de estrógenosModerada

    …accepted to prolong QT interval include Class 1A (e.g., quinidine, procainamide, disopyramide) and Class III (e.g., amiodarone, sotalol, ibutilide, dofetilide) antiarrhythmics; certain antipsychotics (e.g., thioridazine, haloperidol); certain antidepressants (e.g., venlafaxine, amitriptyline); certain antibiotics (e.g., erythromycin, clarithromycin, levofloxacin,… (etiqueta de Toremifeno, Interacciones medicamentosas)

  • Toxina botulínica tipo Abloqueador neuromuscularModerada

    Aminoglycosides or other agents interfering with neuromuscular transmission Anticholinergic drugs Botulinum neurotoxin products Muscle relaxants Aminoglycoside antibiotics, anticholinergic agents, or any other agents that interfere with neuromuscular transmission may potentiate the effect of DAXXIFY; co-administer only with caution and close observation. (etiqueta de Toxina botulínica tipo A, Interacciones medicamentosas)

  • Toxina incobotulínica Abloqueador neuromuscularModerada

    Because of its anticholinergic effects, XEOMIN should be used with caution in patients at risk of developing narrow angle glaucoma. (etiqueta de Toxina incobotulínica A, Advertencias y precauciones)

  • Toxina onabotulínica Abloqueador neuromuscularModerada

    Anticholinergic Drugs Use of anticholinergic drugs after administration of BOTOX may potentiate systemic anticholinergic effects. (etiqueta de Toxina onabotulínica A, Interacciones medicamentosas)

  • TrazodonaantidepresivoModerada

    …are inhibitors of CYP3A4 (e.g., itraconazole, clarithromycin, voriconazole), or known to prolong QT interval including Class 1A antiarrhythmics (e.g., quinidine, procainamide) or Class 3 antiarrhythmics (e.g., amiodarone, sotalol), certain antipsychotic medications (e.g., ziprasidone, chlorpromazine, thioridazine), and certain antibiotics (e.g., gatifloxacin). (etiqueta de Trazodona, Advertencias y precauciones)

  • Triamterenodiurético ahorrador de potasioModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Triamtereno e hidroclorotiazidadiurético ahorrador de potasioModerada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • TrifluoperazinaantipsicóticoModerada

    To lessen the likelihood of adverse reactions related to cumulative drug effect, patients with a history of long-term therapy with prochlorperazine and/or other antipsychotics should be evaluated periodically to decide whether the maintenance dosage could be lowered, or drug therapy discontinued. (etiqueta de Proclorperazina, Precauciones)

  • TrospioanticolinérgicoModerada

    Trospium chloride extended-release capsules, like other antimuscarinic agents, may decrease gastrointestinal motility and should be used with caution in patients with conditions such as ulcerative colitis, intestinal atony and myasthenia gravis. (etiqueta de Trospio, Advertencias y precauciones)

  • Valsartán e hidroclorotiazidaantagonista de los receptores de la angiotensina II (ARA-II)Moderada

    Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

  • Vibegrónagonista beta-adrenérgicoModerada

    Urinary Retention : Monitor for urinary retention, especially in patients with bladder outlet obstruction and also in patients taking muscarinic antagonist medications for OAB, in whom the risk of urinary retention may be greater. (etiqueta de Vibegrón, Advertencias y precauciones)

  • VigabatrinaanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

  • Voriconazolantifúngico azólicoModerada

    Eszopiclone (CYP3A4 Inhibition) Not Studied In Vivo or In Vitro , but Drug Plasma Exposure Likely to be Increased which may Increase the Sedative Effect of Eszopiclone Dose reduction of eszopiclone is recommended. (etiqueta de Voriconazol, Interacciones medicamentosas)

  • ZonisamidaanticonvulsivoModerada

    Phenothiazines may lower the convulsive threshold; dosage adjustments of anticonvulsants may be necessary. (etiqueta de Proclorperazina, Precauciones)

Menciones leves (79)

  • AcebutololbetabloqueanteLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • AliskirenoantihipertensivoLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Amitriptilinaantidepresivo tricíclicoLeve

    Guanethidine or similarly acting compounds; thyroid medication; alcohol, barbiturates and other CNS depressants; and disulfiram – see WARNINGS section. (etiqueta de Amitriptilina, Interacciones medicamentosas)

  • Amlodipinobloqueador de los canales de calcio dihidropiridínicoLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Amlodipino y atorvastatinabloqueador de los canales de calcio dihidropiridínicoLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Amlodipino y benazeprilbloqueador de los canales de calcio dihidropiridínicoLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Amlodipino y olmesartánbloqueador de los canales de calcio dihidropiridínicoLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Amlodipino y valsartánbloqueador de los canales de calcio dihidropiridínicoLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • ApixabánanticoagulanteLeve

    Phenothiazines can diminish the effect of oral anticoagulants. (etiqueta de Proclorperazina, Precauciones)

  • ArgatrobánanticoagulanteLeve

    Phenothiazines can diminish the effect of oral anticoagulants. (etiqueta de Proclorperazina, Precauciones)

  • AtenololbetabloqueanteLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Atomoxetinainhibidor de la recaptación de noradrenalinaLeve

    Some cases presented with features resembling neuroleptic malignant syndrome. (etiqueta de Atomoxetina, Interacciones medicamentosas)

  • Azilsartánantagonista de los receptores de la angiotensina II (ARA-II)Leve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Benazeprilinhibidor de la ECALeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • BenzatropinaanticolinérgicoLeve

    When benztropine mesylate is given concomitantly with phenothiazines, haloperidol, or other drugs with anticholinergic or antidopaminergic activity, patients should be advised to report gastrointestinal complaints, fever or heat intolerance promptly. (etiqueta de Benzatropina, Advertencias)

  • BetaxololbetabloqueanteLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • BisoprololbetabloqueanteLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • BivalirudinaanticoagulanteLeve

    Phenothiazines can diminish the effect of oral anticoagulants. (etiqueta de Proclorperazina, Precauciones)

  • Candesartánantagonista de los receptores de la angiotensina II (ARA-II)Leve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Captoprilinhibidor de la ECALeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • CarvedilolbetabloqueanteLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Cevimelinaagonista colinérgicoLeve

    Cevimeline might interfere with desirable antimuscarinic effects of drugs used concomitantly. (etiqueta de Cevimelina, Interacciones medicamentosas)

  • DabigatránanticoagulanteLeve

    Phenothiazines can diminish the effect of oral anticoagulants. (etiqueta de Proclorperazina, Precauciones)

  • Concurrent treatment with prochlorperazine may lead to temporary impairment of consciousness. (etiqueta de Deferoxamina, Interacciones medicamentosas)

  • Dexanfetaminaestimulante del SNCLeve

    Antihistamines Amphetamines may counteract the sedative effect of antihistamines. (etiqueta de Dexanfetamina, Interacciones medicamentosas)

  • Diltiazembloqueador de los canales de calcioLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Donepeziloinhibidor de la colinesterasaLeve

    Cholinesterase inhibitors have the potential to interfere with the activity of anticholinergic medications ( 7.1 ) (etiqueta de Donepezilo, Interacciones medicamentosas)

  • In Drug-Induced CNS and Respiratory Depression Doxapram alone may not stimulate adequate spontaneous breathing or provide sufficient arousal in patients who are severely depressed either due to respiratory failure or to CNS depressant drugs, but may be used as an adjunct to established supportive measures and resuscitative techniques. (etiqueta de Doxapram, Advertencias)

  • DoxazosinaalfabloqueanteLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • EdoxabánanticoagulanteLeve

    Phenothiazines can diminish the effect of oral anticoagulants. (etiqueta de Proclorperazina, Precauciones)

  • Enalaprilinhibidor de la ECALeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Enalaprilatoinhibidor de la ECALeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • EnoxaparinaanticoagulanteLeve

    Phenothiazines can diminish the effect of oral anticoagulants. (etiqueta de Proclorperazina, Precauciones)

  • The “gasping syndrome” is characterized by central nervous system (CNS) depression, metabolic acidosis, and gasping respirations. (etiqueta de Epoetina alfa, Advertencias y precauciones)

  • Felodipinobloqueador de los canales de calcio dihidropiridínicoLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • FenilefrinadescongestionanteLeve

    If a vasoconstrictor is required, Levophed ® * and Neo-Synephrine ® † are suitable. (etiqueta de Proclorperazina, Precauciones)

  • FenoxibenzaminaalfabloqueanteLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • FondaparinuxanticoagulanteLeve

    Phenothiazines can diminish the effect of oral anticoagulants. (etiqueta de Proclorperazina, Precauciones)

  • Fosinoprilinhibidor de la ECALeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Galantaminainhibidor de la colinesterasaLeve

    Potential to interfere with the activity of anticholinergic medications ( 7.1 ) (etiqueta de Galantamina, Interacciones medicamentosas)

  • Granisetrónfármaco que prolonga el intervalo QTLeve

    There have been no definitive drug-drug interaction studies to examine pharmacokinetic or pharmacodynamic interaction with other drugs; however, in humans, granisetron hydrochloride injection has been safely administered with drugs representing benzodiazepines, neuroleptics and anti-ulcer medications commonly prescribed with antiemetic treatments. (etiqueta de Granisetrón, Interacciones medicamentosas)

  • HeparinaanticoagulanteLeve

    Phenothiazines can diminish the effect of oral anticoagulants. (etiqueta de Proclorperazina, Precauciones)

  • HidralazinavasodilatadorLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Atypical Antipsychotics (e.g., olanzapine and clozapine), Corticosteroids, Danazol, Diuretics, Estrogens, Glucagon, Isoniazid, Niacin, Oral Contraceptives, Phenothiazines, Progestogens (e.g., in oral contraceptives), Protease inhibitors, Somatropin, Sympathomimetic Agents (e.g., albuterol, epinephrine, terbutaline) and Thyroid Hormones. (etiqueta de Insulina regular (humana), Interacciones medicamentosas)

  • Irbesartánantagonista de los receptores de la angiotensina II (ARA-II)Leve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Isradipinobloqueador de los canales de calcio dihidropiridínicoLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • LabetalolbetabloqueanteLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Lisinoprilinhibidor de la ECALeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Losartánantagonista de los receptores de la angiotensina II (ARA-II)Leve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • MecamilaminaantihipertensivoLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Memantina y donepeziloinhibidor de la colinesterasaLeve

    NAMZARIC may interfere with anticholinergic medications. (etiqueta de Memantina y donepezilo, Interacciones medicamentosas)

  • MetildopaantihipertensivoLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • MetoprololbetabloqueanteLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • MinoxidilvasodilatadorLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Moexiprilinhibidor de la ECALeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • NadololbetabloqueanteLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • NebivololbetabloqueanteLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • NefazodonaantidepresivoLeve

    Some cases presented with features resembling neuroleptic malignant syndrome. (etiqueta de Nefazodona, Advertencias)

  • Nicardipinobloqueador de los canales de calcio dihidropiridínicoLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Nifedipinobloqueador de los canales de calcio dihidropiridínicoLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Nisoldipinobloqueador de los canales de calcio dihidropiridínicoLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • NitroprusiatovasodilatadorLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Olmesartánantagonista de los receptores de la angiotensina II (ARA-II)Leve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Perindoprilinhibidor de la ECALeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • PindololbetabloqueanteLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • PrazosinaalfabloqueanteLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Quinaprilinhibidor de la ECALeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Ramiprilinhibidor de la ECALeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • RepaglinidameglitinidaLeve

    Examples: Atypical antipsychotics (e.g., olanzapine and clozapine), calcium channel antagonists, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, oral contraceptives, phenothiazines, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and… (etiqueta de Repaglinida, Interacciones medicamentosas)

  • RivaroxabánanticoagulanteLeve

    Phenothiazines can diminish the effect of oral anticoagulants. (etiqueta de Proclorperazina, Precauciones)

  • Sacubitrilo y valsartánantagonista de los receptores de la angiotensina II (ARA-II)Leve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Telmisartánantagonista de los receptores de la angiotensina II (ARA-II)Leve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Telmisartán y amlodipinoantagonista de los receptores de la angiotensina II (ARA-II)Leve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • TerazosinaalfabloqueanteLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Trandolaprilinhibidor de la ECALeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Valsartánantagonista de los receptores de la angiotensina II (ARA-II)Leve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • Verapamilobloqueador de los canales de calcioLeve

    Antihypertensive effects of guanethidine and related compounds may be counteracted when phenothiazines are used concomitantly. (etiqueta de Proclorperazina, Precauciones)

  • WarfarinaanticoagulanteLeve

    Phenothiazines can diminish the effect of oral anticoagulants. (etiqueta de Proclorperazina, Precauciones)

Sin interacción significativa según la etiqueta (2)

  • LenacapavirantirretroviralSin interacción

    Sedatives/Hypnotics: midazolam (oral) triazolam ↑ midazolam (oral) ↑ triazolam Use with caution when midazolam or triazolam is concomitantly administered with SUNLENCA 7.4 Drugs without Clinically Significant Interactions with SUNLENCA Based on drug interaction studies conducted with SUNLENCA, no clinically significant drug interactions have been observed with:… (etiqueta de Lenacapavir, Interacciones medicamentosas)

  • Montelukastantagonista de los receptores de leucotrienosSin interacción

    …adjustment is needed when SINGULAIR is co-administered with theophylline, prednisone, prednisolone, oral contraceptives, fexofenadine, digoxin, warfarin, gemfibrozil, itraconazole, thyroid hormones, sedative hypnotics, non-steroidal anti-inflammatory agents, benzodiazepines, decongestants, and Cytochrome P450 (CYP) enzyme inducers [see Clinical Pharmacology (12.3) ]. (etiqueta de Montelukast, Interacciones medicamentosas)

Compruebe Proclorperazina frente a todo lo que toma. Añada su lista completa; todos los pares se comprueban a la vez.

Abrir en el verificador

No es un consejo médico. La gravedad refleja la redacción de la etiqueta, no sus circunstancias. Una señal «grave» puede ser algo habitual bajo supervisión y una «leve» puede ser importante a dosis altas. Consulte a un farmacéutico.