Interacciones de Espironolactona e hidroclorotiazida

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)

Antikaliuretic Therapy or Potassium Supplementation Amiloride HCl should not be given to patients receiving other potassium-conserving agents, such as spironolactone or triamterene. (etiqueta de Amilorida, Contraindicaciones)

Lotensin HCT is also contraindicated in patients who are hypersensitive to benazepril, to any other ACE inhibitor, to hydrochlorothiazide, or to other sulfonamide-derived drugs. (etiqueta de Benazepril e hidroclorotiazida, Contraindicaciones)

Sodium bicarbonate injection is contraindicated in patients who are losing chloride by vomiting or from continuous gastrointestinal suction and in patients receiving diuretics known to produce a hypochloremic alkalosis. (etiqueta de Bicarbonato de sodio, Contraindicaciones)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)

Triple combination of candesartan cilexetil with an ACE-inhibitor and a mineralocorticoid receptor antagonist is generally not recommended. (etiqueta de Candesartán, Interacciones medicamentosas)

Potassium-Sparing Diuretics Cyclosporine should not be used with potassium-sparing diuretics because hyperkalemia can occur. (etiqueta de Ciclosporina, Interacciones medicamentosas)

Information for patients Patients who receive spironolactone and hydrochlorothiazide tablets should be advised to avoid potassium supplements and foods containing high levels of potassium including salt substitutes. (etiqueta de Espironolactona e hidroclorotiazida, Precauciones)

Information for patients Patients who receive spironolactone and hydrochlorothiazide tablets should be advised to avoid potassium supplements and foods containing high levels of potassium including salt substitutes. (etiqueta de Espironolactona e hidroclorotiazida, Precauciones)

Use CLOZARIL cautiously in patients with cardiovascular or cerebrovascular disease or conditions predisposing to hypotension (e.g., dehydration, use of antihypertensive medications) [see Dosage and Administration ( 2.2 , 2.6 ), Warnings and Precautions ( 5.2 )]. (etiqueta de Clozapina, Advertencia en recuadro)

Because the use of diuretics can accentuate the diminished intravascular volume, avoid diuretics except in the late phase of resolution. (etiqueta de Coriogonadotropina alfa, Advertencias)

CONTRAINDICATIONS PROGLYCEM is contraindicated in patients with: Functional hypoglycemia Hypersensitivity to diazoxide, any of the excipients in PROGLYCEM, or other thiazides (etiqueta de Diazóxido, Contraindicaciones)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)

Thiazide-induced electrolyte disturbances, i.e. hypokalemia, hypomagnesemia, increase the risk of digoxin toxicity, which may lead to fatal arrhythmic events (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

The concomitant use of hydrochlorothiazide (alone or in combinations such as with triamterene) with dofetilide is contraindicated (see PRECAUTIONS, Drug-Drug Interactions ) because this has been shown to significantly increase dofetilide plasma concentrations and QT interval prolongation. (etiqueta de Dofetilida, Contraindicaciones)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)

Droperidol should be administered with extreme caution to patients who may be at risk for development of prolonged QT syndrome (e.g., congestive heart failure, bradycardia, use of a diuretic, cardiac hypertrophy, hypokalemia, hypomagnesemia, or administration of other drugs known to increase the QT interval). (etiqueta de Droperidol, Advertencia en recuadro)

Avoid potassium sparing agents in patients with heart failure ( 7.3 ). (etiqueta de Enalapril, Interacciones medicamentosas)

…sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include those with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (etiqueta de Enalaprilato, Advertencias)

…serum creatinine > 2.0 mg/dL in males or >1.8 mg/dL in females, • creatinine clearance < 50 mL/min, or • concomitant administration of potassium supplements or potassium-sparing diuretics (e.g., amiloride, spironolactone, or triamterene) [see Warnings and Precautions (5.1) , Adverse Reactions (6.2) , Drug Interactions (7) , and Clinical Pharmacology (12.3) ] . (etiqueta de Eplerenona, Contraindicaciones)

…of active abnormal bleeding within the previous 30 days Severe hypertension (systolic blood pressure >200 mm Hg or diastolic blood pressure >110 mm Hg) not adequately controlled on antihypertensive therapy Major surgery within the preceding 6 weeks History of stroke within 30 days or any history of hemorrhagic stroke Current or planned administration of another… (etiqueta de Eptifibatida, Contraindicaciones)

Information for patients Patients who receive spironolactone and hydrochlorothiazide tablets should be advised to avoid potassium supplements and foods containing high levels of potassium including salt substitutes. (etiqueta de Espironolactona e hidroclorotiazida, Precauciones)

Because the use of diuretics can accentuate the diminished intravascular volume, diuretics should be avoided except in the late phase of resolution as described below. (etiqueta de Folitropina, Advertencias y precauciones)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)

The concurrent use of gentamicin with potent diuretics, such as ethacrynic acid or furosemide, should be avoided, since certain diuretics by themselves may cause ototoxicity. (etiqueta de Gentamicina, Advertencia en recuadro)

Avoid diuretics or laxatives in patients with diarrhea. (etiqueta de Irinotecán, Advertencias y precauciones)

Diuretics Eplerenone Contraindicated during and 2 weeks after TOLSURA treatment. (etiqueta de Itraconazol, Interacciones medicamentosas)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)

Other Antihypertensive Drugs When metolazone tablets, USP, are used with other antihypertensive drugs, particular care must be taken to avoid excessive reduction of blood pressure, especially during initial therapy. (etiqueta de Metolazona, Advertencias)

Minoxidil should be reserved for hypertensive patients who do not respond adequately to maximum therapeutic doses of a diuretic and two other antihypertensive agents. (etiqueta de Minoxidil, Advertencia en recuadro)

Mitotane: Avoid concomitant use of spironolactone and hydrochlorothiazide tablets and mitotane. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Information for patients Patients who receive spironolactone and hydrochlorothiazide tablets should be advised to avoid potassium supplements and foods containing high levels of potassium including salt substitutes. (etiqueta de Espironolactona e hidroclorotiazida, Precauciones)

The concurrent use of neomycin with potent diuretics such as ethacrynic acid or furosemide should be avoided, since certain diuretics by themselves may cause ototoxicity. (etiqueta de Neomicina, Advertencia en recuadro)

…2 , Drug Interactions (7.3) ] ) • Immunosuppressants: voclosporin • Microsomal triglyceride transfer protein inhibitor: lomitapide • Migraine medications: eletriptan, ubrogepant • Mineralocorticoid receptor antagonists: finerenone • Non-opioid analgesic (selective blocker of Na v 1.8 sodium channels): suzetrigine • Opioid antagonists: naloxegol • PDE5 inhibitor:… (etiqueta de Nirmatrelvir y ritonavir, Contraindicaciones)

Information for patients Patients who receive spironolactone and hydrochlorothiazide tablets should be advised to avoid potassium supplements and foods containing high levels of potassium including salt substitutes. (etiqueta de Espironolactona e hidroclorotiazida, Precauciones)

…blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements • diet rich in potassium • salt substitutes containing potassium Spironolactone and hydrochlorothiazide tablets should not be administered concurrently with other… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…sometimes associated with oliguria and/or progressive azotemia, and rarely with acute renal failure and/or death, include patients with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis, or severe volume and/or salt depletion of any etiology. (etiqueta de Quinapril, Advertencias)

…sometimes associated with oliguria and/or progressive azotemia, and rarely acute renal failure and/or death, include patients with the following conditions or characteristics: heart failure, hyponatremia, high dose diuretic therapy, recent intensive diuresis or increase in diuretic dose, renal dialysis or severe volume and/or salt depletion of any etiology. (etiqueta de Quinapril e hidroclorotiazida, Advertencias)

Information for patients Patients who receive spironolactone and hydrochlorothiazide tablets should be advised to avoid potassium supplements and foods containing high levels of potassium including salt substitutes. (etiqueta de Espironolactona e hidroclorotiazida, Precauciones)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)

…coadministration of an alpha-blocker and CIALIS for the treatment of BPH has not been adequately studied, and due to the potential vasodilatory effects of combined use resulting in blood pressure lowering, the combination of CIALIS and alpha-blockers is not recommended for the treatment of BPH. [see Dosage and Administration ( 2.7 ), Drug Interactions ( 7.1 ),… (etiqueta de Tadalafilo, Advertencias y precauciones)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)

Information for patients Patients who receive spironolactone and hydrochlorothiazide tablets should be advised to avoid potassium supplements and foods containing high levels of potassium including salt substitutes. (etiqueta de Espironolactona e hidroclorotiazida, Precauciones)

Information for patients Patients who receive spironolactone and hydrochlorothiazide tablets should be advised to avoid potassium supplements and foods containing high levels of potassium including salt substitutes. (etiqueta de Espironolactona e hidroclorotiazida, Precauciones)

The risk of torsade de pointes is related to the extent of QTc prolongation, concomitant administration of QTc prolonging drugs, a history of torsade de pointes, pre-existing QTc interval prolongation, congestive heart failure, administration of potassium-wasting diuretics, or other conditions that result in hypokalemia or hypomagnesemia. (etiqueta de Trióxido de arsénico, Advertencias y precauciones)

CONTRAINDICATIONS Spironolactone and hydrochlorothiazide tablets are contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison's disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. (etiqueta de Espironolactona e hidroclorotiazida, Contraindicaciones)

Abiraterone: Spironolactone binds to the androgen receptor and may increase prostate‑specific antigen (PSA) levels in abiraterone-treated prostate cancer patients. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Elderly patients and those receiving diuretic therapy are at increased risk of acute renal failure. (etiqueta de Ácido zoledrónico, Advertencias y precauciones)

…Precautions (5.6) and Adverse Reactions (6) ]. β-blockers, such as propranolol Cyclopropane or halogenated hydrocarbon anesthetics, such as halothane Antihistamines Thyroid hormones Diuretics Cardiac glycosides, such as digitalis glycosides Quinidine Drugs potentiating hypokalemic effects of epinephrine • Potassium depleting diuretics • Corticosteroids • Theophylline… (etiqueta de Adrenalina, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Postural hypotension/syncope: Care should be taken in patients with symptomatic hypotension or who have had a hypotensive response to other medications or are concomitantly treated with antihypertensive medication or nitrates ( 5.1 ) (etiqueta de Alfuzosina, Advertencias y precauciones)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Hypersensitivity reactions to allopurinol tablets may be increased in patients with decreased kidney function receiving thiazide diuretics and allopurinol tablets concurrently. (etiqueta de Alopurinol, Advertencias y precauciones)

Ethacrynic Acid, Furosemide, Urea, or Mannitol Some diuretics can enhance aminoglycoside toxicity by altering aminoglycoside concentrations in serum and tissue. (etiqueta de Amikacina, Interacciones medicamentosas)

Give special attention to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or in patients receiving concomitant diuretics and laxatives. (etiqueta de Amiodarona, Advertencias y precauciones)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

The pressor effects of diethylpropion and those of other drugs may be additive when the drugs are used concomitantly; conversely, diethylpropion may interfere with antihypertensive drugs (i.e., guanethidine, a-methyldopa). (etiqueta de Anfepramona, Interacciones medicamentosas)

Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (etiqueta de Arformoterol, Interacciones medicamentosas)

Antihypertensive Drugs Due to its alpha-adrenergic antagonism, aripiprazole has the potential to enhance the effect of certain antihypertensive agents. (etiqueta de Aripiprazol, Interacciones medicamentosas)

There was also a slightly greater proportion of patients on NUVIGIL requiring new or increased use of antihypertensive medications (2.9%) compared to patients on placebo (1.8%). (etiqueta de Armodafinilo, Advertencias y precauciones)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medications, patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), and patients… (etiqueta de Asenapina, Advertencias y precauciones)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Concomitant administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Antihypertensive Drugs Prevention or Management Increase the frequency of monitoring blood pressure and adjust atomoxetine oral solution dosage as clinically appropriate. (etiqueta de Atomoxetina, Interacciones medicamentosas)

• Use of avanafil with alpha-blockers, other antihypertensives, or substantial amounts of alcohol (greater than 3 units) may lead to hypotension ( 2.3 , 5.6 , 5.7 ) (etiqueta de Avanafilo, Advertencias y precauciones)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine): Possible increased responsiveness to the muscle relaxant may result. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Amphetamines may decrease the hypotensive effect of antihypertensives. (etiqueta de Benzfetamina, Interacciones medicamentosas)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Abiraterone: Spironolactone binds to the androgen receptor and may increase prostate‑specific antigen (PSA) levels in abiraterone-treated prostate cancer patients. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Concomitant administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Hypotension: Use caution when treating patients taking antihypertensives, with a history of syncope, or with dehydration. (etiqueta de Bortezomib, Advertencias y precauciones)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, concomitant treatment with antihypertensive medication), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etiqueta de Brexpiprazol, Advertencias y precauciones)

Antihypertensives/Cardiac Glycosides Because brimonidine tartrate ophthalmic solution 0.1% and 0.15% may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate ophthalmic solution 0.1% and 0.15% is advised. (etiqueta de Brimonidina, Interacciones medicamentosas)

Antihypertensives/Cardiac Glycosides Because brimonidine tartrate/timolol maleate ophthalmic solution may reduce blood pressure, caution in using drugs such as antihypertensives and/or cardiac glycosides with brimonidine tartrate/timolol maleate ophthalmic solution is advised. (etiqueta de Brimonidina y timolol, Interacciones medicamentosas)

Central Nervous System (CNS) depressants Antihistamines have additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, antianxiety agents, etc.). Antihypertensive drugs Sympathomimetic may reduce the effects of antihypertensive drugs. (etiqueta de Bromfeniramina, pseudoefedrina y dextrometorfano, Interacciones medicamentosas)

Use caution in patients taking antihypertensive medications. (etiqueta de Bromocriptina, Advertencias y precauciones)

Diuretics: Use with caution. (etiqueta de Budesonida y formoterol, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Thiazides Thiazides are known to induce hypercalcemia by the reduction of calcium excretion in urine. (etiqueta de Calcitriol, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Elderly patients and patients treated with diuretics are at greater risk of developing hyponatremia. (etiqueta de Carbamazepina, Advertencias y precauciones)

Symptomatic postural hypotension has occurred when carbidopa, given with levodopa or carbidopa-levodopa combination products, was added to the treatment of a patient receiving antihypertensive drugs. (etiqueta de Carbidopa, Interacciones medicamentosas)

Antihypertensive drugs: May cause symptomatic postural hypotension. (etiqueta de Carbidopa y levodopa, Interacciones medicamentosas)

Antihypertensive Agents Symptomatic postural hypotension has occurred when carbidopa/levodopa was added to the treatment of patients receiving antihypertensive drugs. (etiqueta de Carbidopa, levodopa y entacapona, Interacciones medicamentosas)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etiqueta de Cariprazina, Advertencias y precauciones)

Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine): Possible increased responsiveness to the muscle relaxant may result. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Diuretics: Nephrotoxicity has been reported with concomitant administration of cephalosporins with potent diuretics such as furosemide. (etiqueta de Cefepima, Interacciones medicamentosas)

Drug Interactions Nephrotoxicity has been reported following concomitant administration of cephalosporins with aminoglycoside antibacterial drugs or potent diuretics such as furosemide. (etiqueta de Ceftazidima, Interacciones medicamentosas)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine): Possible increased responsiveness to the muscle relaxant may result. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…inhibitors: ACE inhibitors can cause leukopenia. ● Natalizumab ● Paclitaxel: Increased hematotoxicity has been reported when cyclophosphamide was administered after paclitaxel infusion. ● Thiazide diuretics ● Zidovudine Increased cardiotoxicity ● Anthracyclines ● Cytarabine ● Pentostatin ● Radiation therapy of the cardiac region ● Trastuzumab Increased pulmonary toxicity… (etiqueta de Ciclofosfamida, Interacciones medicamentosas)

Increase the dose of diuretics as needed [see Adverse Reactions (6) ] . (etiqueta de Ciclosilicato de sodio y zirconio, Advertencias y precauciones)

Elderly patients, patients taking diuretics, and those who are volume depleted may be at greater risk for developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (etiqueta de Citalopram, Advertencias y precauciones)

Consider use of diuretics and/or albumin. (etiqueta de Clofarabina, Advertencias y precauciones)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Concomitant administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Clorpromazina, Precauciones)

Concomitant administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Drugs That Increase the Risk of Hypercalcemia Increase frequency of monitoring of calcium concentrations in patients taking concomitant Calcium Chloride Injection and other drugs that increase the risk of hypercalcemia (e.g., calcipotriene, estrogen, lithium, parathyroid hormone, teriparatide, thiazide diuretics, Vitamin A, and Vitamin D). (etiqueta de Cloruro de calcio, Interacciones medicamentosas)

Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine): Possible increased responsiveness to the muscle relaxant may result. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

The absorption of tetracycline, furosemide, penicillin G, hydrochlorothiazide, and gemfibrozil was significantly decreased when given simultaneously with colestipol hydrochloride; these drugs were not tested to determine the effect of administration one hour before colestipol hydrochloride. (etiqueta de Colestipol, Interacciones medicamentosas)

Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (etiqueta de Colestiramina, Interacciones medicamentosas)

Abiraterone: Spironolactone binds to the androgen receptor and may increase prostate‑specific antigen (PSA) levels in abiraterone-treated prostate cancer patients. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine): Possible increased responsiveness to the muscle relaxant may result. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with NORPRAMIN. (etiqueta de Desipramina, Advertencias)

…Hyponatremia Concomitant administration of DESMODA with other drugs that may increase the risk of water intoxication with hyponatremia, (e.g., tricyclic antidepressants, selective serotonin re-uptake inhibitors, chlorpromazine, opiate analgesics, thiazide diuretics, NSAIDs, lamotrigine, sulfonylureas, particularly chlorpropamide, oxybutynin and carbamazepine). (etiqueta de Desmopresina, Interacciones medicamentosas)

Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk [see Use in Specific Populations (8.5) and Clinical Pharmacology (12.3) ] . (etiqueta de Desvenlafaxina, Advertencias y precauciones)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etiqueta de Dexlansoprazol, Advertencias y precauciones)

• Antihypertensive Drugs: Monitor blood pressure. (etiqueta de Dexmetilfenidato, Interacciones medicamentosas)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Risk may be increased when used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (etiqueta de Doxercalciferol, Advertencias y precauciones)

…[See Adverse Reactions ( 6 ).] Figure 1: VTE Risk with Yasmin Relative to LNG-Containing COCs (adjusted risk#) Figure 2 Likelihood of Developing a VTE 5.2 Hyperkalemia Yaz contains 3 mg of the progestin DRSP which has anti-mineralocorticoid activity, including the potential for hyperkalemia in high-risk patients, comparable to a 25 mg dose of spironolactone. (etiqueta de Drospirenona y etinilestradiol, Advertencias y precauciones)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

The risk of BP decreases may be greater in patients taking concomitant medications that induce orthostatic hypotension (such as antihypertensives) or are potent CYP1A2 inhibitors [see Drug Interactions ( 7.1 )] and in patients taking duloxetine delayed-release capsules at doses above 60 mg daily. (etiqueta de Duloxetina, Advertencias y precauciones)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements • diet rich in potassium • salt substitutes containing potassium Spironolactone… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Following initiation and titration of Epogen, approximately 25% of patients on dialysis required initiation of or increases in antihypertensive therapy; hypertensive encephalopathy and seizures have been reported in patients with CKD receiving Epogen. (etiqueta de Epoetina alfa, Advertencias y precauciones)

Additional reductions in blood pressure may occur when VELETRI is administered with diuretics, antihypertensive agents, or other vasodilators. (etiqueta de Epoprostenol, Interacciones medicamentosas)

Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (etiqueta de Escitalopram, Advertencias y precauciones)

Antihypertensive agents clonidine, guanfacine, or moxonidine: Beta blockers also increase the risk of clonidine-, guanfacine-, or moxonidine-withdrawal rebound hypertension. (etiqueta de Esmolol, Interacciones medicamentosas)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etiqueta de Esomeprazol, Advertencias y precauciones)

Concomitant administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Abiraterone: Spironolactone binds to the androgen receptor and may increase prostate‑specific antigen (PSA) levels in abiraterone-treated prostate cancer patients. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…hydrochloride desipramine hydrochloride imipramine hydrochloride doxepin carbamazepine cyclobenzaprine HCl amoxapine maprotiline HCl trimipramine maleate protriptyline HCl mirtazapine Phenelzine sulfate should be used with caution in combination with antihypertensive drugs, including thiazide diuretics and β-blockers, since exaggerated hypotensive effects may result. (etiqueta de Fenelzina, Advertencias)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Concomitant administration of hydrochlorothiazide alone with topiramate alone has been shown to increase the C max and AUC of topiramate by 27% and 29%, respectively. (etiqueta de Fentermina y topiramato, Interacciones medicamentosas)

Hydrochlorothiazide In a pharmacokinetic interaction study, coadministration of multiple-dose hydrochlorothiazide to healthy volunteers receiving fluconazole increased plasma concentrations of fluconazole by 40%. (etiqueta de Fluconazol, Interacciones medicamentosas)

Amphotericin B or potassium-depleting diuretics (benzothiadiazines and related drugs, ethacrynic acid and furosemide)—enhanced hypokalemia. (etiqueta de Fludrocortisona, Interacciones medicamentosas)

Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (etiqueta de Fluoxetina, Advertencias y precauciones)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Abiraterone: Spironolactone binds to the androgen receptor and may increase prostate‑specific antigen (PSA) levels in abiraterone-treated prostate cancer patients. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Diuretics: Use with caution. (etiqueta de Fluticasona y salmeterol, Interacciones medicamentosas)

Also, patients taking diuretics or who are otherwise volume depleted may be at greater risk. (etiqueta de Fluvoxamina, Advertencias y precauciones)

• Xanthine derivatives, steroids, diuretics, or non-potassium sparing diuretics may potentiate hypokalemia or ECG changes. (etiqueta de Formoterol, Interacciones medicamentosas)

When diuretics are indicated, thiazides are recommended over loop diuretics because the latter inhibit renal tubular secretion, and may impair elimination of FOSCAVIR, potentially leading to toxicity. (etiqueta de Foscarnet, Interacciones medicamentosas)

…administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Caution is advised when haloperidol decanoate is used in combination with drugs known to cause electrolyte imbalance (e.g., diuretics or corticosteroids) because hypokalemia, hypomagnesemia, and hypocalcemia are risk factors for QT prolongation. (etiqueta de Haloperidol, Interacciones medicamentosas)

…potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements • diet rich in potassium • salt substitutes containing potassium Spironolactone… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Concomitant administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive medications), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and… (etiqueta de Iloperidona, Advertencias y precauciones)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with imipramine hydrochloride tablets. (etiqueta de Imipramina, Advertencias)

Concomitant administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Spironolactone, when used with ACE inhibitors or indomethacin, even in the presence of a diuretic, has been associated with severe hyperkalemia. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Diuretics The electrocardiogram (ECG) changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by β-agonists, especially when the recommended dose of the β-agonist is exceeded. (etiqueta de Ipratropio y salbutamol, Interacciones medicamentosas)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Diuretics eplerenone The potential increase in plasma concentrations of eplerenone when coadministered with ketoconazole tablets may increase the risk of hyperkalemia and hypotension. (etiqueta de Ketoconazol, Interacciones medicamentosas)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ] . (etiqueta de Lansoprazol, Advertencias y precauciones)

Also, patients taking diuretics or who are otherwise volume depleted can be at greater risk. (etiqueta de Levomilnaciprán, Advertencias y precauciones)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Diuretics The ECG changes or hypokalemia that may result from the administration of non-potassium-sparing diuretics (such as loop and thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (etiqueta de Levosalbutamol, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Monitor serum sodium levels regularly in the elderly, in patients taking diuretics, and in other patients at risk of hyponatremia and/or SIADH while taking Linezolid injection. (etiqueta de Linezolid, Advertencias y precauciones)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Lithium generally should not be given with diuretics (see Precautions: Drug interactions ). (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Caution should also be exercised if an HMG-CoA reductase inhibitor or other agent used to lower cholesterol levels is administered to patients also receiving other drugs (e.g., spironolactone, cimetidine) that may decrease the levels or activity of endogenous steroid hormones. (etiqueta de Lovastatina, Interacciones medicamentosas)

Orthostatic vital signs should be monitored in patients who are vulnerable to hypotension (e.g., elderly patients, patients with dehydration, hypovolemia, and concomitant treatment with antihypertensive drugs), patients with known cardiovascular disease (history of myocardial infarction, ischemic heart disease, heart failure, or conduction abnormalities), and patients… (etiqueta de Lumateperona, Advertencias y precauciones)

Patients at increased risk of these adverse reactions or at increased risk of developing complications from hypotension include those with dehydration, hypovolemia, treatment with antihypertensive medication, history of cardiovascular disease (e.g., heart failure, myocardial infarction, ischemia, or conduction abnormalities), history of cerebrovascular disease,… (etiqueta de Lurasidona, Advertencias y precauciones)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine): Possible increased responsiveness to the muscle relaxant may result. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Antihypertensive Drugs: Monitor blood pressure. (etiqueta de Metilfenidato, Interacciones medicamentosas)

Abiraterone: Spironolactone binds to the androgen receptor and may increase prostate‑specific antigen (PSA) levels in abiraterone-treated prostate cancer patients. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine): Possible increased responsiveness to the muscle relaxant may result. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Concomitant administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Geriatric Use ( 8.5 )] . (etiqueta de Milnaciprán, Advertencias y precauciones)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia [see Use in Specific Populations (8.5) ] . (etiqueta de Mirtazapina, Advertencias y precauciones)

However, a retrospective analysis of the use of antihypertensive medication in these studies showed that a greater proportion of patients on PROVIGIL required new or increased use of antihypertensive medications (2.4%) compared to patients on placebo (0.7%). (etiqueta de Modafinilo, Advertencias y precauciones)

…administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Antihypertensive Therapy Niacin may potentiate the effects of ganglionic blocking agents and vasoactive drugs resulting in postural hypotension. (etiqueta de Niacina, Interacciones medicamentosas)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Blood Pressure Lowering Drugs Nimodipine may increase the blood pressure lowering effect of concomitantly administered anti-hypertensives such as diuretics, beta-blockers, ACE inhibitors, angiotensin receptor blockers, other calcium channel blockers, α-adrenergic blockers, PDE5 inhibitors, and α-methyldopa. (etiqueta de Nimodipino, Interacciones medicamentosas)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Antihypertensives: Possible additive hypotensive effects. (etiqueta de Nitroglicerina, Interacciones medicamentosas)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, and conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications) where the occurrence of syncope, or hypotension and/or bradycardia might put the patient at increased medical risk. (etiqueta de Olanzapina, Advertencias y precauciones)

…and fluoxetine capsules should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemia, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions that would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (etiqueta de Olanzapina y fluoxetina, Advertencias y precauciones)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (etiqueta de Omeprazol, Advertencias y precauciones)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions ( 6.2 )] . (etiqueta de Omeprazol y bicarbonato de sodio, Advertencias y precauciones)

Skeletal muscle relaxants, nondepolarizing (e.g., tubocurarine): Possible increased responsiveness to the muscle relaxant may result. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Use ERZOFRI with caution in patients with known cardiovascular disease (e.g., heart failure, history of myocardial infarction or ischemia, conduction abnormalities), cerebrovascular disease, or conditions that predispose the patient to hypotension (e.g., dehydration, hypovolemia, and treatment with antihypertensive medications). (etiqueta de Paliperidona, Advertencias y precauciones)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (etiqueta de Pantoprazol, Advertencias y precauciones)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

The risk may be increased when Paricalcitol Injection is used concomitantly with high dose calcium preparations, thiazide diuretics, or vitamin D compounds. (etiqueta de Paricalcitol, Advertencias y precauciones)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SNRIs and SSRIs. [see Use in Specific Populations ( 8.5 )]. (etiqueta de Paroxetina, Advertencias y precauciones)

Monitor blood pressure as clinically indicated and initiate and adjust antihypertensive therapy as appropriate. (etiqueta de Pazopanib, Advertencias y precauciones)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Small decreases in blood pressure have been observed in some patients treated with pentoxifylline extended-release tablets; periodic systemic blood pressure monitoring is recommended for patients receiving concomitant antihypertensive therapy. (etiqueta de Pentoxifilina, Interacciones medicamentosas)

…administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Proclorperazina, Precauciones)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Quetiapine should be used with particular caution in patients with known cardiovascular disease (history of myocardial infarction or ischemic heart disease, heart failure, or conduction abnormalities), cerebrovascular disease, or conditions which would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications). (etiqueta de Quetiapina, Advertencias y precauciones)

Drugs that alkalinize the urine ( carbonic-anhydrase inhibitors, sodium bicarbonate, thiazide diuretics ) reduce renal elimination of quinidine. (etiqueta de Quinidina, Interacciones medicamentosas)

For patients expected to be on prolonged treatment or who take PPIs with medications such as digoxin or drugs that may cause hypomagnesemia (e.g., diuretics), health care professionals may consider monitoring magnesium levels prior to initiation of PPI treatment and periodically [see Adverse Reactions (6.2) ]. (etiqueta de Rabeprazol, Advertencias y precauciones)

…administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Consider the potential for symptomatic hypotension or ischemia in patients with hypovolemia, severe left ventricular outflow obstruction, resting hypotension, autonomic dysfunction, or concomitant treatment with antihypertensives or strong CYP and P-gp/BCRP inhibitors [see Drug Interactions (7.2) and Clinical Pharmacology (12.3) ] . (etiqueta de Riociguat, Advertencias y precauciones)

Clinically significant hypotension has been observed with concomitant use of oral RISPERDAL and antihypertensive medication. (etiqueta de Risperidona, Advertencias y precauciones)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Diuretics: Use with caution. (etiqueta de Salbutamol, Interacciones medicamentosas)

• Diuretics: Use with caution. (etiqueta de Salmeterol, Interacciones medicamentosas)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs [see Use in Specific Populations ( 8.5 )] . (etiqueta de Sertralina, Advertencias y precauciones)

Caution is advised when SILDENAFIL ORAL FILM is co-administered with alpha-blockers or antihypertensives. (etiqueta de Sildenafilo, Advertencias y precauciones)

However, patients in the Phase 3 clinical studies taking concomitant antihypertensive medications with silodosin capsules did not experience a significant increase in the incidence of syncope, dizziness, or orthostasis. (etiqueta de Silodosina, Advertencias y precauciones)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Consider temporary or permanent discontinuation for severe or persistent hypertension despite antihypertensive therapy. (etiqueta de Sorafenib, Advertencias y precauciones)

Special attention should be given to electrolyte and acid-base balance in patients experiencing severe or prolonged diarrhea or patients receiving concomitant diuretic drugs. (etiqueta de Sotalol, Advertencias y precauciones)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Initiate and/or adjust antihypertensive therapy as appropriate. (etiqueta de Sunitinib, Advertencias y precauciones)

Prolonged Neuromuscular Block in Patients with Hypokalemia or Hypocalcemia Neuromuscular blockade may be prolonged in patients with hypokalemia (e.g., after severe vomiting, diarrhea, digitalisation and diuretic therapy) or hypocalcemia (e.g., after massive transfusions). (etiqueta de Suxametonio (succinilcolina), Advertencias y precauciones)

• Hypertension: May require antihypertensive therapy; monitor relevant drug interactions. (etiqueta de Tacrolimus, Advertencias y precauciones)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Diuretics The ECG changes and/or hypokalemia that may result from the administration of non-potassium sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. (etiqueta de Terbutalina, Precauciones)

Abiraterone: Spironolactone binds to the androgen receptor and may increase prostate‑specific antigen (PSA) levels in abiraterone-treated prostate cancer patients. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Antidiabetic drugs (e.g., oral agents, insulin): Dosage adjustment of the antidiabetic drug may be required (see Precautions ). (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Some diuretics can enhance aminoglycoside toxicity by altering antibiotic concentrations in serum and tissue. (etiqueta de Tobramicina, Interacciones medicamentosas)

…following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs or conditions known to cause hyperkalemia • potassium supplements… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Co-administration of diuretics also increases the risk of too rapid correction of serum sodium and such patients should undergo close monitoring of serum sodium. (etiqueta de Tolvaptán, Advertencias y precauciones)

Hydrochlorothiazide (HCTZ) Topiramate C max and AUC increased when HCTZ was added to immediate-release topiramate. (etiqueta de Topiramato, Interacciones medicamentosas)

Drugs that decrease renal calcium excretion, e.g., thiazide diuretics, may increase the risk of hypercalcemia in patients receiving FARESTON. (etiqueta de Toremifeno, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Alcohol, barbiturates, or narcotics: Potentiation of orthostatic hypotension may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

…administration of spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Concomitant use with an antihypertensive may require a reduction in the dose of the antihypertensive drug. (etiqueta de Trazodona, Advertencias y precauciones)

Thiazide diuretics may accentuate the orthostatic hypotension that may occur with phenothiazines. (etiqueta de Trifluoperazina, Precauciones)

• Diuretics: Use with caution. (etiqueta de Umeclidinio y vilanterol, Interacciones medicamentosas)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

…spironolactone and hydrochlorothiazide tablets with the following drugs or potassium sources may lead to severe hyperkalemia: • other potassium-sparing diuretics • ACE inhibitors • angiotensin II receptor antagonists • aldosterone blockers • non-steroidal anti-inflammatory drugs (NSAIDs), e.g., indomethacin • heparin and low molecular weight heparin • other drugs… (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Vardenafil hydrochloride tablets can potentiate the hypotensive effects of nitrates, alpha- blockers, and antihypertensives. (etiqueta de Vardenafilo, Interacciones medicamentosas)

Also, patients taking diuretics or who are otherwise volume-depleted may be at greater risk [see Use in Specific Populations ( 8.5 )] . (etiqueta de Venlafaxina, Advertencias y precauciones)

Thiazides may add to or potentiate the action of other antihypertensive drugs. (etiqueta de Espironolactona e hidroclorotiazida, Advertencias)

Elderly patients, patients taking diuretics, and those who are volume-depleted may be at greater risk of developing hyponatremia with SSRIs and SNRIs [see Use in Specific Populations ( 8.5 )] . (etiqueta de Vilazodona, Advertencias y precauciones)

Los diuréticos tiazídicos reducen la excreción de calcio; combinados con suplementos de vitamina D y de calcio, esto puede llevar a hipercalcemia, sobre todo en adultos mayores. (NIH Office of Dietary Supplements, Vitamin D)

Also, patients taking diuretics or who are otherwise volume-depleted can be at greater risk. (etiqueta de Vortioxetina, Advertencias y precauciones)

Concurrent use with potassium-containing medications, potassium-sparing diuretics and angiotensin-converting enzyme inhibitors (ACE inhibitors) may result in hyperkalemia and cardiac arrhythmias or cardiac arrest. (etiqueta de Yoduro de potasio, Interacciones medicamentosas)

Hypokalemia may result from diuretic therapy, diarrhea, and other causes. (etiqueta de Ziprasidona, Advertencias y precauciones)

Coadministration of 1 Dyazide (triamterene/hydrochlorothiazide) resulted in a higher plasma amantadine hydrochloride concentration in a 61-year old man receiving amantadine hydrochloride 100 mg TID for Parkinson's disease. (etiqueta de Amantadina, Interacciones medicamentosas)

Patients required intervention with a diuretic, fluid management, or, in some cases, hospitalization for decompensating heart failure. (etiqueta de Ambrisentán, Advertencias y precauciones)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Patients required intervention with a diuretic, fluid management, or hospitalization for decompensating heart failure. (etiqueta de Bosentán, Advertencias y precauciones)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Los diuréticos tiazídicos reducen la excreción de calcio, por lo que una ingesta alta de calcio puede elevar el calcio en sangre. (NIH Office of Dietary Supplements, Calcium)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Acthar Gel may accentuate the electrolyte loss associated with diuretic therapy. (etiqueta de Corticotropina, Interacciones medicamentosas)

Fluid retention events were typically managed by supportive care measures that may include diuretics or short courses of steroids. (etiqueta de Dasatinib, Advertencias y precauciones)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

If other contraceptive methods are not suitable, hormonal contraceptive therapy may continue combined with antihypertensive therapy. (etiqueta de Desogestrel y etinilestradiol, Advertencias)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Examples of alkalinizing agents include gastrointestinal alkalinizing agents (e.g., sodium bicarbonate) and urinary alkalinizing agents (e.g. acetazolamide, some thiazides). (etiqueta de Dexanfetamina, Interacciones medicamentosas)

Drug Interactions There was no evidence of drug interactions in clinical studies in which dobutamine was administered concurrently with other drugs, including digitalis preparations, furosemide, spironolactone, lidocaine, glyceryl trinitrate, isosorbide dinitrate, morphine, atropine, heparin, protamine, potassium chloride, folic acid, and acetaminophen. (etiqueta de Dobutamina, Interacciones medicamentosas)

Patients developing peripheral edema may be treated with standard measures, e.g., salt restriction, oral diuretic(s). (etiqueta de Docetaxel, Advertencias y precauciones)

Hypokalemia and Hypomagnesemia with Potassium-Depleting Diuretics Hypokalemia or hypomagnesemia may occur with concomitant administration of potassium-depleting diuretics. (etiqueta de Dronedarona, Advertencias y precauciones)

Examples: α-adrenergic antagonists, β-adrenergic receptor antagonists, reserpine, quinidine, mephentermine Other Drug Interactions G u anethidine C linical Impact: Ephedrine may inhibit the neuron blockage produced by guanethidine, resulting in loss of antihypertensive effectiveness. (etiqueta de Efedrina, Interacciones medicamentosas)

In Vivo Drug Interaction Studies Based on drug interaction studies in healthy patients, ULORIC does not have clinically significant interactions with colchicine, naproxen, indomethacin, hydrochlorothiazide, warfarin or desipramine [see Clinical Pharmacology (12.3) ]. (etiqueta de Febuxostat, Interacciones medicamentosas)

…clinical studies with acetaminophen, acetylsalicylic acid, α-blockers, angiotensin-converting enzyme (ACE) inhibitors, analgesics, anti-convulsants, beta-adrenergic blocking agents, diuretics, calcium channel blockers, cardiac nitrates, HMG-CoA reductase inhibitors, nonsteroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, H 2 antagonists and quinolone anti-infectives… (etiqueta de Finasterida, Interacciones medicamentosas)

Flecainide acetate has been used in a large number of patients receiving diuretics without apparent interaction. (etiqueta de Flecainida, Interacciones medicamentosas)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Drugs that may cause hypercalcemia: Vitamin D, vitamin A, thiazide diuretics, estrogen, calcipotriene and teriparatide administration may cause hypercalcemia. (etiqueta de Gluconato de calcio, Interacciones medicamentosas)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

ACE Inhibitors FIRAZYR is a bradykinin B2 receptor antagonist and thereby has the potential to have a pharmacodynamic interaction with ACE inhibitors where FIRAZYR may attenuate the antihypertensive effect of ACE inhibitors. (etiqueta de Icatibant, Interacciones medicamentosas)

Weigh patients regularly and manage unexpected rapid weight gain by drug interruption and diuretics. (etiqueta de Imatinib, Advertencias y precauciones)

Postmarketing cases of edema and fluid retention occurring within weeks of starting OPSUMIT, some requiring intervention with a diuretic or hospitalization for decompensated heart failure, have been reported [see Adverse Reactions (6.2) ] . (etiqueta de Macitentán, Advertencias y precauciones)

El uso a largo plazo de diuréticos de asa y diuréticos tiazídicos aumenta la pérdida de magnesio por la orina. (NIH Office of Dietary Supplements, Magnesium)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

In a large compassionate use program mexiletine has been used concurrently with commonly employed antianginal, antihypertensive, and anticoagulant drugs without observed interactions. (etiqueta de Mexiletina, Interacciones medicamentosas)

…been observed in limited experience with patients in whom milrinone was used concurrently with the following drugs: digitalis glycosides; lidocaine, quinidine; hydralazine, prazosin; isosorbide dinitrate, nitroglycerin; chlorthalidone, furosemide, hydrochlorothiazide, spironolactone; captopril; heparin, warfarin, diazepam, insulin; and potassium supplements. (etiqueta de Milrinona, Interacciones medicamentosas)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

The antihypertensive action of guanethidine and similar agents may be blocked. (etiqueta de Nortriptilina, Advertencias)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Management of pseudoaldosteronism may include discontinuation of Noxafil, substitution with an appropriate antifungal drug that is not associated with pseudoaldosteronism, or use of aldosterone receptor antagonists. (etiqueta de Posaconazol, Advertencias y precauciones)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Protriptyline may block the antihypertensive effect of guanethidine or similarly acting compounds. (etiqueta de Protriptilina, Advertencias)

There is no information available from adequate drug-drug interaction studies with the following classes of drugs: oral contraceptives, hormone replacement therapies, hypoglycemics, phenytoins, thiazide diuretics, and calcium channel blockers. (etiqueta de Terbinafina, Interacciones medicamentosas)

Corticosteroids, ACTH: Intensified electrolyte depletion, particularly hypokalemia, may occur. (etiqueta de Espironolactona e hidroclorotiazida, Interacciones medicamentosas)

Los diuréticos tiazídicos aumentan la pérdida de zinc por la orina con el uso a largo plazo. (NIH Office of Dietary Supplements, Zinc)

Loop Diuretics Concomitant administration of a loop diuretic had no effect on the calcium-lowering action of pamidronate disodium. (etiqueta de Pamidronato, Interacciones medicamentosas)

Commonly Administered Drugs: Population analysis showed that commonly administered drugs (e.g., selegiline, amantadine, tricyclic antidepressants, benzodiazepines, ibuprofen, thiazides, antihistamines, anticholinergics) did not affect the clearance of ropinirole. (etiqueta de Ropinirol, Interacciones medicamentosas)