Pipéracilline et tazobactam : interactions médicamenteuses

AMOXIL is contraindicated in patients who have experienced a serious hypersensitivity reaction (e.g., anaphylaxis or Stevens-Johnson syndrome) to AMOXIL or to other β-lactam antibacterial drugs (e.g., penicillins and cephalosporins). (notice Amoxicilline, Contre-indications)

History of a serious hypersensitivity reaction (e.g., anaphylaxis or Stevens-Johnson syndrome) to AUGMENTIN or to other beta‑lactams (e.g., penicillins or cephalosporins). (notice Amoxicilline et acide clavulanique, Contre-indications)

CONTRAINDICATIONS The use of Ampicillin is contraindicated in individuals with a history of serious hypersensitivity reactions (e.g., anaphylaxis or Stevens-Johnson syndrome) to ampicillin or to other beta-lactam antibacterial drugs. (notice Ampicilline, Contre-indications)

CONTRAINDICATIONS The use of UNASYN is contraindicated in individuals with a history of serious hypersensitivity reactions (e.g., anaphylaxis or Stevens-Johnson syndrome) to ampicillin, sulbactam or to other beta-lactam antibacterial drugs (e.g., penicillins and cephalosporins). (notice Ampicilline et sulbactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection is contraindicated in patients with a history of allergic reactions to any of the penicillins, cephalosporins, or betalactamase inhibitors. (notice Pipéracilline et tazobactam, Contre-indications)

Since bacteriostatic drugs may interfere with the bactericidal action of penicillins, it is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. (notice Déméclocycline, Interactions médicamenteuses)

Avoid co-administration of tetracyclines with penicillin. (notice Doxycycline, Interactions médicamenteuses)

INVANZ is contraindicated in patients with known hypersensitivity to any component of this product or to other drugs in the same class or in patients who have demonstrated anaphylactic reactions to beta-lactams. (notice Ertapénem, Contre-indications)

Hypersensitivity Reactions: Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams. (notice Imipénem et cilastatine, Mises en garde et précautions)

Penicillin Because bacteriostatic drugs may interfere with the bactericidal action of penicillin, avoid giving EMROSI in conjunction with penicillin. (notice Minocycline, Interactions médicamenteuses)

Probenecid prolongs the half-lives of piperacillin and tazobactam and should not be co-administered with Piperacillin and Tazobactam for Injection and Sodium Chloride Injection unless the benefit outweighs the risk. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Probenecid prolongs the half-lives of piperacillin and tazobactam and should not be co-administered with Piperacillin and Tazobactam for Injection and Sodium Chloride Injection unless the benefit outweighs the risk. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Drug Interactions Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline in conjunction with penicillin or other bactericidal antibacterials. (notice Tétracycline, Interactions médicamenteuses)

In vivo inactivation : When aminoglycosides are administered in conjunction with piperacillin to patients with end-stage renal disease requiring hemodialysis, the concentrations of the aminoglycosides (especially tobramycin) may be significantly reduced and should be monitored. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Monitor coagulation parameters in patients receiving Piperacillin and Tazobactam for Injection and Sodium Chloride Injection and heparin or oral anticoagulants. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Monitor coagulation parameters in patients receiving Piperacillin and Tazobactam for Injection and Sodium Chloride Injection and heparin or oral anticoagulants. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection may prolong the neuromuscular blockade of vecuronium and other non-depolarizing neuromuscular blockers. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Use caution when CAYSTON is administered to patients with a known allergic reaction to beta-lactams. (notice Aztréonam, Mises en garde et précautions)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Bénazépril et hydrochlorothiazide, Mises en garde)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Bisoprolol et hydrochlorothiazide, Mises en garde)

Monitor coagulation parameters in patients receiving Piperacillin and Tazobactam for Injection and Sodium Chloride Injection and heparin or oral anticoagulants. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Candésartan et hydrochlorothiazide, Mises en garde)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection may prolong the neuromuscular blockade of vecuronium and other non-depolarizing neuromuscular blockers. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

The absorption of tetracycline, furosemide, penicillin G, hydrochlorothiazide, and gemfibrozil was significantly decreased when given simultaneously with colestipol hydrochloride; these drugs were not tested to determine the effect of administration one hour before colestipol hydrochloride. (notice Colestipol, Interactions médicamenteuses)

Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (notice Colestyramine, Interactions médicamenteuses)

Monitor coagulation parameters in patients receiving Piperacillin and Tazobactam for Injection and Sodium Chloride Injection and heparin or oral anticoagulants. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Drugs that Cause Hypokalemia The risk of hypokalemia is greater with coadministration of KEVEYIS and other drugs that can cause hypokalemia (e.g., loop diuretics, thiazide diuretics, laxatives, antifungals, penicillins, and theophylline) [see Warnings and Precautions (5.3) ] . (notice Diclofénamide, Interactions médicamenteuses)

Nephrotoxicity in critically ill patients has been observed; the use of piperacillin and tazobactam was found to be an independent risk factor for renal failure and was associated with delayed recovery of renal function as compared to other beta-lactam antibacterial drugs in a randomized, multicenter, controlled trial in critically ill patients. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Monitor coagulation parameters in patients receiving Piperacillin and Tazobactam for Injection and Sodium Chloride Injection and heparin or oral anticoagulants. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Énalapril et hydrochlorothiazide, Mises en garde)

Monitor coagulation parameters in patients receiving Piperacillin and Tazobactam for Injection and Sodium Chloride Injection and heparin or oral anticoagulants. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Monitor coagulation parameters in patients receiving Piperacillin and Tazobactam for Injection and Sodium Chloride Injection and heparin or oral anticoagulants. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Increased Transaminase Levels In Trial 1, increases in transaminases occurred more frequently in CONTEPO-treated patients compared to piperacillin/tazobactam-treated patients. (notice Fosfomycine, Mises en garde et précautions)

In vivo inactivation : When aminoglycosides are administered in conjunction with piperacillin to patients with end-stage renal disease requiring hemodialysis, the concentrations of the aminoglycosides (especially tobramycin) may be significantly reduced and should be monitored. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Monitor coagulation parameters in patients receiving Piperacillin and Tazobactam for Injection and Sodium Chloride Injection and heparin or oral anticoagulants. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Hydrochlorothiazide, Mises en garde et précautions)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection may prolong the neuromuscular blockade of vecuronium and other non-depolarizing neuromuscular blockers. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Irbésartan et hydrochlorothiazide, Mises en garde et précautions)

In patients taking ARAVA, exposure of drugs which are OAT3 substrates (e.g., cefaclor, cimetidine, ciprofloxacin, penicillin G, ketoprofen, furosemide, methotrexate, zidovudine) may be increased. (notice Léflunomide, Interactions médicamenteuses)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Lisinopril et hydrochlorothiazide, Mises en garde)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Losartan et hydrochlorothiazide, Mises en garde et précautions)

Methotrexate Limited data suggests that co-administration of methotrexate and piperacillin may reduce the clearance of methotrexate due to competition for renal secretion. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Métoprolol et hydrochlorothiazide, Mises en garde et précautions)

Examples Cyclosporine A, trimethoprim/sulfamethoxazole, bile acid sequestrants (cholestyramine), rifampin as well as aminoglycoside, cephalosporin, fluoroquinolone and penicillin classes of antimicrobials Drugs Modulating Glucuronidation Clinical Impact Concomitant use with drugs inducing glucuronidation decreases MPA systemic exposure, potentially reducing mycophenolate… (notice Mycophénolate, Interactions médicamenteuses)

Nephrotoxicity in critically ill patients has been observed; the use of piperacillin and tazobactam was found to be an independent risk factor for renal failure and was associated with delayed recovery of renal function as compared to other beta-lactam antibacterial drugs in a randomized, multicenter, controlled trial in critically ill patients. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

In vivo inactivation : When aminoglycosides are administered in conjunction with piperacillin to patients with end-stage renal disease requiring hemodialysis, the concentrations of the aminoglycosides (especially tobramycin) may be significantly reduced and should be monitored. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Olmésartan et hydrochlorothiazide, Mises en garde et précautions)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Olmésartan, amlodipine et hydrochlorothiazide, Mises en garde et précautions)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection may prolong the neuromuscular blockade of vecuronium and other non-depolarizing neuromuscular blockers. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Nephrotoxicity in critically ill patients has been observed; the use of piperacillin and tazobactam was found to be an independent risk factor for renal failure and was associated with delayed recovery of renal function as compared to other beta-lactam antibacterial drugs in a randomized, multicenter, controlled trial in critically ill patients. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Nephrotoxicity in critically ill patients has been observed; the use of piperacillin and tazobactam was found to be an independent risk factor for renal failure and was associated with delayed recovery of renal function as compared to other beta-lactam antibacterial drugs in a randomized, multicenter, controlled trial in critically ill patients. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Nephrotoxicity in critically ill patients has been observed; the use of piperacillin and tazobactam was found to be an independent risk factor for renal failure and was associated with delayed recovery of renal function as compared to other beta-lactam antibacterial drugs in a randomized, multicenter, controlled trial in critically ill patients. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

In vivo inactivation : When aminoglycosides are administered in conjunction with piperacillin to patients with end-stage renal disease requiring hemodialysis, the concentrations of the aminoglycosides (especially tobramycin) may be significantly reduced and should be monitored. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Drug Interactions Protamine sulfate has been shown to be incompatible with certain antibiotics, including several of the cephalosporins and penicillins (see DOSAGE AND ADMINISTRATION ). (notice Protamine, Précautions)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Quinapril et hydrochlorothiazide, Mises en garde)

Monitor coagulation parameters in patients receiving Piperacillin and Tazobactam for Injection and Sodium Chloride Injection and heparin or oral anticoagulants. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection may prolong the neuromuscular blockade of vecuronium and other non-depolarizing neuromuscular blockers. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Salicylate competes with a number of drugs for protein binding sites, notably penicillin, thiopental, thyroxine, triiodothyronine, phenytoin, sulfinpyrazone, naproxen, warfarin, methotrexate, and possibly corticosteroids. [When Salsalate tablets, USP are administered with aspirin, its protein binding is reduced, although the clearance of free Salsalate tablets,… (notice Salsalate, Interactions médicamenteuses)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Spironolactone et hydrochlorothiazide, Mises en garde)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection may prolong the neuromuscular blockade of vecuronium and other non-depolarizing neuromuscular blockers. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Telmisartan et hydrochlorothiazide, Mises en garde et précautions)

In patients taking AUBAGIO, exposure of drugs which are OAT3 substrates (e.g., cefaclor, cimetidine, ciprofloxacin, penicillin G, ketoprofen, furosemide, methotrexate, zidovudine) may be increased. (notice Tériflunomide, Interactions médicamenteuses)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection administration can significantly reduce tobramycin concentrations in hemodialysis patients. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Piperacillin and Tazobactam for Injection and Sodium Chloride Injection may prolong the neuromuscular blockade of vecuronium and other non-depolarizing neuromuscular blockers. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

…from blood bank (may contain up to 30 mEq of potassium per liter of plasma or up to 65 mEq per liter of whole blood when stored for more than 10 days); low-salt milk (may contain up to 60 mEq of potassium per liter); potassium-containing medications (such as parenteral penicillin G potassium); salt substitutes (most contain substantial amounts of potassium). (notice Triamtérène, Interactions médicamenteuses)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Triamtérène et hydrochlorothiazide, Mises en garde)

Risk factors for developing acute angle-closure glaucoma may include a history of sulfonamide or penicillin allergy. (notice Valsartan et hydrochlorothiazide, Mises en garde et précautions)

Combined use of piperacillin and tazobactam and vancomycin may be associated with an increased incidence of acute kidney injury [see Drug Interactions (7.3) ]. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Vecuronium Piperacillin when used concomitantly with vecuronium has been implicated in the prolongation of the neuromuscular blockade of vecuronium. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Monitor coagulation parameters in patients receiving Piperacillin and Tazobactam for Injection and Sodium Chloride Injection and heparin or oral anticoagulants. (notice Pipéracilline et tazobactam, Interactions médicamenteuses)

Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Infants born to women treated during pregnancy with oral erythromycin for early syphilis should be treated with an appropriate penicillin regimen. (notice Érythromycine, Mises en garde)

Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

There have been reports of individuals with a history of penicillin hypersensitivity who have experienced severe hypersensitivity reactions when treated with another β-lactam. (notice Méropénem, Mises en garde et précautions)

Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Patients who are allergic to penicillin may theoretically have cross-sensitivity to penicillamine. (notice Pénicillamine, Précautions)

Some antibiotics such as penicillin may compete with phenylacetylglutamine and hippurate for active secretion by renal tubules, which may affect the overall disposition of the infused drug. (notice Phénylacétate de sodium et benzoate de sodium, Interactions médicamenteuses)

Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (notice Pipéracilline et tazobactam, Mises en garde et précautions)

Periodic electrolyte determinations should be performed in patients with low potassium reserves, and the possibility of hypokalemia should be kept in mind with patients who have potentially low potassium reserves and who are receiving cytotoxic therapy or diuretics. (notice Pipéracilline et tazobactam, Mises en garde et précautions)