Tétracycline : interactions médicamenteuses

Tétracycline (Sumycin, Achromycin), antibiotique de la famille des tétracyclines, présente 76 interactions documentées dans les notices FDA et les fiches d'information que nous indexons : 19 de niveau majeur, 28 de niveau modéré, 26 de niveau mineur et 3 cas où une notice ne signale aucune interaction significative. Chaque entrée ci-dessous cite la phrase sur laquelle elle repose. Cette page consacrée à un médicament est un point de départ, pas un verdict sur votre situation.

Interactions d'après la notice

Interactions majeures (19)

  • AcitrétinerétinoïdeMajeure

    Concomitant use of isotretinoin and tetracycline should be avoided because isotretinoin, a systemic retinoid, is also known to cause pseudotumor cerebri. (notice Tétracycline, Mises en garde)

  • AdapalènerétinoïdeMajeure

    Concomitant use of isotretinoin and tetracycline should be avoided because isotretinoin, a systemic retinoid, is also known to cause pseudotumor cerebri. (notice Tétracycline, Mises en garde)

  • Amoxicillineantibiotique de la famille des pénicillinesMajeure

    Drug Interactions Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline in conjunction with penicillin or other bactericidal antibacterials. (notice Tétracycline, Interactions médicamenteuses)

  • Amoxicilline et acide clavulaniqueantibiotique de la famille des pénicillinesMajeure

    Drug Interactions Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline in conjunction with penicillin or other bactericidal antibacterials. (notice Tétracycline, Interactions médicamenteuses)

  • Ampicillineantibiotique de la famille des pénicillinesMajeure

    Drug Interactions Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline in conjunction with penicillin or other bactericidal antibacterials. (notice Tétracycline, Interactions médicamenteuses)

  • Ampicilline et sulbactamantibiotique de la famille des pénicillinesMajeure

    Drug Interactions Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline in conjunction with penicillin or other bactericidal antibacterials. (notice Tétracycline, Interactions médicamenteuses)

  • BexarotènerétinoïdeMajeure

    Concomitant use of isotretinoin and tetracycline should be avoided because isotretinoin, a systemic retinoid, is also known to cause pseudotumor cerebri. (notice Tétracycline, Mises en garde)

  • Déméclocyclineantibiotique de la famille des tétracyclinesMajeure

    CONTRAINDICATIONS This drug is contraindicated in persons who have shown hypersensitivity to any of the tetracyclines or any of the components of the product formulation. (notice Déméclocycline, Contre-indications)

  • Dicloxacillineantibiotique de la famille des pénicillinesMajeure

    Drug Interactions Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline in conjunction with penicillin or other bactericidal antibacterials. (notice Tétracycline, Interactions médicamenteuses)

  • Doxycyclineantibiotique de la famille des tétracyclinesMajeure

    Doxycycline hyclate are contraindicated in persons who have shown hypersensitivity to any of the tetracyclines. (notice Doxycycline, Contre-indications)

  • IsotrétinoïnerétinoïdeMajeure

    Concomitant use of isotretinoin and tetracycline should be avoided because isotretinoin, a systemic retinoid, is also known to cause pseudotumor cerebri. (notice Tétracycline, Mises en garde)

  • Minocyclineantibiotique de la famille des tétracyclinesMajeure

    EMROSI is contraindicated in patients with a history of hypersensitivity to any of the tetracyclines [see Warnings and Precautions (5.1) ]. (notice Minocycline, Contre-indications)

  • Nafcillineantibiotique de la famille des pénicillinesMajeure

    Drug Interactions Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline in conjunction with penicillin or other bactericidal antibacterials. (notice Tétracycline, Interactions médicamenteuses)

  • Oxacillineantibiotique de la famille des pénicillinesMajeure

    Drug Interactions Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline in conjunction with penicillin or other bactericidal antibacterials. (notice Tétracycline, Interactions médicamenteuses)

  • Pénicilline Gantibiotique de la famille des pénicillinesMajeure

    Drug Interactions Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline in conjunction with penicillin or other bactericidal antibacterials. (notice Tétracycline, Interactions médicamenteuses)

  • Pénicilline Vantibiotique de la famille des pénicillinesMajeure

    Drug Interactions Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline in conjunction with penicillin or other bactericidal antibacterials. (notice Tétracycline, Interactions médicamenteuses)

  • Pipéracilline et tazobactamantibiotique de la famille des pénicillinesMajeure

    Drug Interactions Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline in conjunction with penicillin or other bactericidal antibacterials. (notice Tétracycline, Interactions médicamenteuses)

  • Tigécyclineantibiotique de la famille des tétracyclinesMajeure

    Avoid use in patients with known hypersensitivity to tetracyclines. (notice Tigécycline, Mises en garde et précautions)

  • TrétinoïnerétinoïdeMajeure

    Concomitant use of isotretinoin and tetracycline should be avoided because isotretinoin, a systemic retinoid, is also known to cause pseudotumor cerebri. (notice Tétracycline, Mises en garde)

Interactions modérées (28)

  • Acétate de calciumchélateur du phosphateModérée

    Calcium acetate capsules may decrease the bioavailability of tetracyclines or fluoroquinolones via this mechanism. (notice Acétate de calcium, Interactions médicamenteuses)

  • ApixabananticoagulantModérée

    Because the tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (notice Tétracycline, Interactions médicamenteuses)

  • ArgatrobananticoagulantModérée

    Because the tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (notice Tétracycline, Interactions médicamenteuses)

  • AtovaquoneantipaludiqueModérée

    • Concomitant administration of tetracycline reduces atovaquone concentrations; use caution when coadministering. (notice Atovaquone, Interactions médicamenteuses)

  • Atovaquone et proguanilantipaludiqueModérée

    • Tetracycline may reduce atovaquone concentrations; parasitemia should be closely monitored. (notice Atovaquone et proguanil, Interactions médicamenteuses)

  • BivalirudineanticoagulantModérée

    Because the tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (notice Tétracycline, Interactions médicamenteuses)

  • CalciumVitamines et minérauxModérée

    Le calcium se lie à ces médicaments dans l'intestin et peut fortement réduire la quantité absorbée ; espacez les prises. (NIH Office of Dietary Supplements, Calcium)

  • Colestipolchélateur des acides biliairesModérée

    The absorption of tetracycline, furosemide, penicillin G, hydrochlorothiazide, and gemfibrozil was significantly decreased when given simultaneously with colestipol hydrochloride; these drugs were not tested to determine the effect of administration one hour before colestipol hydrochloride. (notice Colestipol, Interactions médicamenteuses)

  • Colestyraminechélateur des acides biliairesModérée

    Drug Interactions Cholestyramine for Oral Suspension USP may delay or reduce the absorption of concomitant oral medication such as phenylbutazone, warfarin, thiazide diuretics (acidic), or propranolol (basic), as well as tetracycline, penicillin G, phenobarbital, thyroid and thyroxine preparations, estrogens and progestins, and digitalis. (notice Colestyramine, Interactions médicamenteuses)

  • DabigatrananticoagulantModérée

    Because the tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (notice Tétracycline, Interactions médicamenteuses)

  • ÉdoxabananticoagulantModérée

    Because the tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (notice Tétracycline, Interactions médicamenteuses)

  • ÉnoxaparineanticoagulantModérée

    Because the tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (notice Tétracycline, Interactions médicamenteuses)

  • FerVitamines et minérauxModérée

    Le fer se lie à ces médicaments dans l'intestin et réduit leur absorption ; espacez les prises. (NIH Office of Dietary Supplements, Iron)

  • FondaparinuxanticoagulantModérée

    Because the tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (notice Tétracycline, Interactions médicamenteuses)

  • Glimépiridesulfamide hypoglycémiantModérée

    …antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides,… (notice Glimépiride, Interactions médicamenteuses)

  • HéparineanticoagulantModérée

    Because the tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (notice Tétracycline, Interactions médicamenteuses)

  • Lanthanechélateur du phosphateModérée

    Examples of relevant classes of compounds where antacids have been demonstrated to reduce bioavailability include antibiotics (such as quinolones, ampicillin, and tetracyclines), thyroid hormones, ACE inhibitors, statin lipid regulators, and anti-malarials. (notice Lanthane, Interactions médicamenteuses)

  • LomitapideModérée

    Caution should be exercised when JUXTAPID is used with other medications known to have potential for hepatotoxicity, such as isotretinoin, amiodarone, acetaminophen (>4 g/day for ≥3 days/week), methotrexate, tetracyclines, and tamoxifen. (notice Lomitapide, Mises en garde et précautions)

  • MagnésiumVitamines et minérauxModérée

    Les compléments et les antiacides contenant du magnésium réduisent l'absorption de ces médicaments ; espacez les prises d'au moins deux heures. (NIH Office of Dietary Supplements, Magnesium)

  • Pioglitazone et glimépiridethiazolidinedioneModérée

    …antagonists, fibrates, propoxyphene, pentoxifylline, somatostatin analogs, anabolic steroids and androgens, cyclophosphamide, phenyramidol, guanethidine, fluconazole, sulfinpyrazone, tetracyclines, clarithromycin, disopyramide, quinolones, and those drugs that are highly protein-bound, such as fluoxetine, nonsteroidal anti-inflammatory drugs, salicylates, sulfonamides,… (notice Pioglitazone et glimépiride, Interactions médicamenteuses)

  • Quinaprilinhibiteur de l'enzyme de conversion (IEC)Modérée

    Tetracycline and other drugs that interact with magnesium Simultaneous administration of tetracycline with quinapril hydrochloride reduced the absorption of tetracycline by approximately 28% to 37%, possibly due to the high magnesium content in quinapril tablets. (notice Quinapril, Interactions médicamenteuses)

  • QuinineantipaludiqueModérée

    Although tetracycline may be concomitantly administered with quinine sulfate, patients should be monitored closely for adverse reactions associated with quinine sulfate. (notice Quinine, Interactions médicamenteuses)

  • RivaroxabananticoagulantModérée

    Because the tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (notice Tétracycline, Interactions médicamenteuses)

  • Rocuroniumbloquant neuromusculaireModérée

    Antibiotics Drugs which may enhance the neuromuscular blocking action of nondepolarizing agents such as Rocuronium Bromide Injection include certain antibiotics (e.g., aminoglycosides; vancomycin; tetracyclines; bacitracin; polymyxins; colistin; and sodium colistimethate). (notice Rocuronium, Interactions médicamenteuses)

  • As with other antibacterial drugs, use of tetracycline hydrochloride may result in overgrowth of nonsusceptible organisms, including fungi. (notice Sous-citrate de bismuth, métronidazole et tétracycline, Mises en garde et précautions)

  • SucralfateModérée

    Drug Interactions Some studies have shown that simultaneous sucralfate administration in healthy volunteers reduced the extent of absorption (bioavailability) of single doses of the following: cimetidine, digoxin, fluoroquinolone antibiotics, ketoconazole, l-thyroxine, phenytoin, quinidine, ranitidine, tetracycline, and theophylline. (notice Sucralfate, Interactions médicamenteuses)

  • WarfarineanticoagulantModérée

    Because the tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage. (notice Tétracycline, Interactions médicamenteuses)

  • ZincVitamines et minérauxModérée

    Le zinc réduit l'absorption des antibiotiques de la famille des quinolones et des tétracyclines ; prenez l'antibiotique au moins deux heures avant ou quatre à six heures après le zinc. (NIH Office of Dietary Supplements, Zinc)

Mentions mineures (26)

  • Antiacides (Tums, Maalox, Mylanta)Produits sans ordonnanceMineure

    Absorption of tetracyclines is impaired by antacids containing aluminum, calcium or magnesium and preparations containing iron, zinc, or sodium bicarbonate. (notice Tétracycline, Interactions médicamenteuses)

  • Bicarbonate de sodiumantiacideMineure

    Absorption of tetracyclines is impaired by antacids containing aluminum, calcium or magnesium and preparations containing iron, zinc, or sodium bicarbonate. (notice Tétracycline, Interactions médicamenteuses)

  • Désogestrel et éthinylestradiolcontraceptif oralMineure

    Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Drospirénone et éthinylestradiolcontraceptif oralMineure

    Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • EstradiolestrogèneMineure

    Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Estradiol et diénogestcontraceptif oralMineure

    Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Estrogènes conjuguésestrogèneMineure

    Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • FulvestrantestrogèneMineure

    Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • LévonorgestrelprogestatifMineure

    Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Lévonorgestrel et éthinylestradiolcontraceptif oralMineure

    Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • MédroxyprogestéroneprogestatifMineure

    Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • MégestrolprogestatifMineure

    Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Mifépristoneinhibiteur du CYP3A4Mineure

    Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • NoréthistéroneprogestatifMineure

    Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Norgestimate et éthinylestradiolcontraceptif oralMineure

    Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Norgestrel et éthinylestradiolcontraceptif oralMineure

    Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Oméprazole et bicarbonate de sodiuminhibiteur de la pompe à protons (IPP)Mineure

    Absorption of tetracyclines is impaired by antacids containing aluminum, calcium or magnesium and preparations containing iron, zinc, or sodium bicarbonate. (notice Tétracycline, Interactions médicamenteuses)

  • ProgestéroneprogestatifMineure

    Concurrent use of tetracycline may render oral contraceptives less effective. (notice Tétracycline, Interactions médicamenteuses)

  • Vécuroniumbloquant neuromusculaireMineure

    The following antibiotics have been associated with various degrees of paralysis: aminoglycosides (such as neomycin, streptomycin, kanamycin, gentamicin, and dihydrostreptomycin); tetracyclines; bacitracin; polymyxin B; colistin; and sodium colistimethate. (notice Vécuronium, Précautions)

Aucune interaction significative signalée (3)

  • AminophyllineméthylxanthineAucune interaction

    …omeprazole prednisone, prednisolone ranitidine rifabutin roxithromycin sorbitol (purgative doses do not inhibit theophylline absorption) sucralfate terbutaline, systemic terfenadine tetracycline tocainide The Effect of Other Drugs on Theophylline Serum Concentration Measurements: Most serum theophylline assays in clinical use are immunoassays which are specific… (notice Aminophylline, Interactions médicamenteuses)

  • Cisatracuriumbloquant neuromusculaireAucune interaction

    …additional doses of Cisatracurium Besylate Injection, and to determine whether adjustments need to be made to the dose with subsequent administration. † Examples: aminoglycosides, tetracyclines, bacitracin, polymyxins, lincomycin, clindamycin, colistin, sodium colistimethate Drug or Drug Class Clinical Implications * Succinylcholine The use of succinylcholine… (notice Cisatracurium, Interactions médicamenteuses)

  • ThéophyllineméthylxanthineAucune interaction

    …ranitidine famotidine rifabutin felodipine roxithromycin finasteride Sorbitol (purgative doses do not inhibit hydrocortisone theophylline absorption) isoflurane sucralfate isoniazid terbutaline, systemic isradipine terfenadine influenza vaccine tetracycline ketoconazole tocainide lomefloxacin * Refer to PRECAUTIONS , Drug Interactions for information regarding table. (notice Théophylline, Interactions médicamenteuses)

Vérifiez Tétracycline avec tout ce que vous prenez. Ajoutez votre liste complète ; toutes les paires sont vérifiées en une fois.

Ouvrir dans le vérificateur

Ceci n'est pas un avis médical. Le niveau de gravité reflète la formulation de la notice, pas votre situation. Une alerte « majeure » peut être courante sous surveillance et une alerte « mineure » peut compter à forte dose. Demandez conseil à un pharmacien.